Job Description P0AF20 Confidence 99.73% Date Thu Jan 5 11:24:56 GMT 2012 Rank 39 Aligned Residues 334 % Identity 20% Template c3hm8D_ PDB info PDB header:transferase Chain: D: PDB Molecule:hexokinase-3; PDBTitle: crystal structure of the c-terminal hexokinase domain of human hk3 Resolution 2.80 Å

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		37	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.				.	60	.	.	.	.	.	.	.	.	.				70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.
Predicted Secondary structure																								.	.	.												.	.	.																																									.
Query SS confidence																								.	.	.												.	.	.																																									.
Query Sequence		Q	I	A	E	Q	S	Q	L	A	P	A	S	V	T	K	I	T	R	Q	L	I	E	.	.	.	R	G	L	I	K	E	V	D	Q	Q	A	.	.	.	S	T	G	G	R	R	A	I	S	I	V	T	E	T	R	N	F	H	A	I	G	V	R	L	G	R	H	D	A	T	I	T	L	F	D	L	S	S	K	V	.
Query Conservation																								.	.	.												.	.	.																																									.
Alig confidence																								.	.	.												.	.	.										.	.	.	.																												.
Template Conservation																																																		.	.	.	.
Template Sequence		E	T	L	A	P	F	R	L	N	H	D	Q	L	A	A	V	Q	A	Q	M	R	K	A	M	A	K	G	L	R	G	E	A	S	S	L	R	M	L	P	T	F	V	R	A	T	P	D	G	.	.	.	.	S	E	R	G	D	F	L	A	L	D	L	G	G	T	N	F	R	V	L	L	V	R	V	T	T	G	V	Q
Template Known Secondary structure					G	G	G	S																							T	S			S	S									S	S			S	.	.	.	.												S	S	S	S									S	S	S
Template Predicted Secondary structure																																																		.	.	.	.
Template SS confidence
		485	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.					.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560
		110	.	.	.	.	.	.	.	.					.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.		.	.	150	.	.	.	.	.	.	.	.	.	160		.	.	.	.	.	.	.	.	.	170					.	.	.	.	.	.	.	.	.
Predicted Secondary structure											.	.	.	.																														.														.											.	.	.	.
Query SS confidence											.	.	.	.																														.														.											.	.	.	.
Query Sequence		L	A	E	E	H	Y	P	L	P	.	.	.	.	E	R	T	Q	Q	T	L	E	H	A	L	L	N	A	I	A	Q	F	I	D	S	Y	Q	R	K	L	R	E	L	.	I	A	I	S	V	I	L	P	G	L	V	D	P	.	D	S	G	K	I	H	Y	M	P	H	.	.	.	.	I	Q	V	E	N	W	G	L	V
Query Conservation											.	.	.	.																														.														.											.	.	.	.
Alig confidence											.	.	.	.																														.														.											.	.	.	.
Template Conservation
Template Sequence		I	T	S	E	I	Y	S	I	P	E	T	V	A	Q	G	S	G	Q	Q	L	F	D	H	I	V	D	C	I	V	D	F	Q	Q	K	Q	G	L	S	G	Q	S	L	P	L	G	F	T	F	S	F	P	C	R	Q	L	G	L	D	Q	G	I	L	L	N	W	T	K	G	F	K	A	S	D	C	E	G	Q	D	V	V
Template Known Secondary structure															S	S	B																				T		T	T											S							T	T									T	T				B	T		T	T	S	B
Template Predicted Secondary structure
Template SS confidence
		561	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630	.	.	.	.	.	.	.	.	.	640
		180	.	.	.	.	.	.					.	.	.				190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.
Predicted Secondary structure									.	.	.	.				.	.	.
Query SS confidence									.	.	.	.				.	.	.
Query Sequence		E	A	L	E	E	R	F	.	.	.	.	K	V	T	.	.	.	C	F	V	G	H	D	I	R	S	L	A	L	A	E	H	Y	F	G	A	S	Q	D	C	E	D	S	I	L	V	R	V	H	R	G	T	G	A	G	I	I	S	N	G	R	I	F	I	G	R	N	G	N	V	G	E	I	G	H	I	Q	V	E	P
Query Conservation									.	.	.	.				.	.	.
Alig confidence									.	.	.	.				.	.	.																	.	.	.	.																																		.	.	.						.	.
Template Conservation																																			.	.	.	.																																		.	.	.						.	.
Template Sequence		S	L	L	R	E	A	I	T	R	R	Q	A	V	E	L	N	V	V	A	I	V	N	D	T	V	G	T	M	M	S	C	G	Y	.	.	.	.	E	D	P	R	C	E	I	G	L	I	V	G	T	G	T	N	A	C	Y	M	E	E	L	R	N	V	A	G	V	P	G	D	S	.	.	.	G	R	M	C	I	.	.
Template Known Secondary structure												T		S				S																T	.	.	.	.	T		T	T								S	S	S									G	G	G		T	T	S				S	.	.	.	S					.	.
Template Predicted Secondary structure																																			.	.	.	.																																		.	.	.						.	.
Template SS confidence
		641	.	.	.	.	.	.	.	.	650	.	.	.	.	.	.	.	.	.	660	.	.	.	.	.	.	.	.	.	670	.	.	.					.	.	.	.	.	.	680	.	.	.	.	.	.	.	.	.	690	.	.	.	.	.	.	.	.	.	700	.	.	.	.	.	.				.	.	.	710	.
		253	.	.	.	.	.	.	260	.	.	.																											.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.								.	.	.	.	290	.	.	.	.	.	.	.	.	.
Predicted Secondary structure													.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																							.	.	.	.	.	.	.
Query SS confidence													.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																							.	.	.	.	.	.	.
Query Sequence		L	G	E	R	C	H	C	G	N	F	G	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	C	L	E	T	I	A	A	N	A	A	I	E	Q	R	V	L	N	L	L	K	Q	G	.	.	.	.	.	.	.	Y	Q	S	R	V	P	L	D	D	C	T	I	K	T
Query Conservation													.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																							.	.	.	.	.	.	.
Alig confidence		.	.	.									.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																							.	.	.	.	.	.	.
Template Conservation		.	.	.
Template Sequence		.	.	.	N	M	E	W	G	A	F	G	D	D	G	S	L	A	M	L	S	T	R	F	D	A	S	V	D	Q	A	S	I	N	P	G	K	Q	R	F	E	K	M	I	S	G	M	Y	L	G	E	I	V	R	H	I	L	L	H	L	T	S	L	G	V	L	F	I	Q	R	L	Q	T	R	D	I	F	K	T	K	F
Template Known Secondary structure		.	.	.				G	G	G	T	T	T	T	T	T	T	T	T	T											T	S	S	S	T	T	S	S	T	T	G	G	G	T	S																			T	S				G	G	G	G	S	T	T		S
Template Predicted Secondary structure		.	.	.
Template SS confidence
					712	.	.	.	.	.	.	.	720	.	.	.	.	.	.	.	.	.	730	.	.	.	.	.	.	.	.	.	740	.	.	.	.	.	.	.	.	.	750	.	.	.	.	.	.	.	.	.	760	.	.	.	.	.	.	.	.	.	770	.	.	.	.	.	.	.	.	.	780	.	.	.	.	.	.	.	.
		300	.	.	.	.	.	.	.	.	.	310																										.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.									.	.	.	340	.	.	.	.	.	.
Predicted Secondary structure													.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																											.	.	.	.	.	.	.	.
Query SS confidence													.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																											.	.	.	.	.	.	.	.
Query Sequence		I	C	K	A	A	N	K	G	D	S	L	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	A	S	E	V	I	E	Y	V	G	R	H	L	G	K	T	I	A	I	A	I	N	L	F	N	P	Q	.	.	.	.	.	.	.	.	K	I	V	I	A	G	E	I	T	E
Query Conservation													.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																											.	.	.	.	.	.	.	.
Alig confidence													.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																											.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		L	S	E	I	E	S	D	S	L	A	L	R	Q	V	R	A	I	L	E	D	L	G	L	P	L	T	S	D	D	A	L	M	V	L	E	V	C	Q	A	V	S	Q	R	A	A	Q	L	C	G	A	G	V	A	A	V	V	E	K	I	R	E	N	R	G	L	E	E	L	A	V	S	V	G	V	D	G	T	L	Y	K
Template Known Secondary structure						T		T	T												T	T	T																																									T	T		S	S
Template Predicted Secondary structure
Template SS confidence
		793	.	.	.	.	.	.	800	.	.	.	.	.	.	.	.	.	810	.	.	.	.	.	.	.	.	.	820	.	.	.	.	.	.	.	.	.	830	.	.	.	.	.	.	.	.	.	840	.	.	.	.	.	.	.	.	.	850	.	.	.	.	.	.	.	.	.	860	.	.	.	.	.	.	.	.	.	870	.	.
		347	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.
Predicted Secondary structure
Query SS confidence
Query Sequence		A	D	K	V	L	L	P	A	I	E	S	C	I	N	T	Q	A	L	K	A	F	R	T	N	L	P	V	V	R	S	E	L	D	H	R	S	A	I	G	A	F	A	L	V	K
Query Conservation
Alig confidence																			.	.	.	.	.
Template Conservation																			.	.	.	.	.
Template Sequence		L	H	P	R	F	S	S	L	V	A	A	T	V	R	E	L	A	.	.	.	.	.	P	R	C	V	V	T	F	L	Q	S	E	D	G	S	G	K	G	A	A	L	V	T	A
Template Known Secondary structure				T	T														.	.	.	.	.	T	T									S	S
Template Predicted Secondary structure																			.	.	.	.	.
Template SS confidence
		873	.	.	.	.	.	.	880	.	.	.	.	.	.	.	.	.						890	.	.	.	.	.	.	.	.	.	900	.	.	.	.	.	.	.	.	.	910	.	.