|   |
318 | . | 320 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
. | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | |
|
. | . | . | . | . | 380 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|  | . | . | . | . | . | . | . | . |  |  |  |
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  | . | . |
|
|
|
|
|
|  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
R | D | I | K | V | R | D | G | L | . |
. |
. |
. |
. |
. |
. |
. |
F | W | I | N | N | R | Y | V | M | L | H | G | V | N | R | H | D | N | D | H | R | K | G | R | A | V | G | M | D | R | V | E | K | D | L | Q | L | M | K | Q | H | N | I | N | S | V | R | T | . |
. |
A | H | Y | P | N | D | P | R | F | Y | E | L | C |
Query Conservation |   |
|   |
|
|   |   |   |   |   | . | . | . | . | . | . | . | . |
|   |
|
|
|
|   |
|   |
|
|
|
|
|   |
|   |   |   |
|   |   |
|   |   |   |   |   |
|   |   |   |   |
|
|   |
|
|
|   |   |
|   |
|   |
|
|   | . | . |
|
|
|
|   |   |   |   |
|
|
|
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |
|
|
|   |   |   |   |
|
|
|   |
|   |   |   |   |   |   |   |   |   | . |   |   |   |   |
|   |   |   |   |   |
|   |   |   |
|   |   |
|   |
|   |
|
|   |   |   |   |   |   |
|   |   |   |   |
|   |
|   |
|
Template Sequence |   |
R | T | I | R | V | V | N | E | K | D | K | D | G | E | S | F | Y | F | E | V | N | G | I | P | M | F | A | K | G | A | N | Y | I | P | Q | D | A | L | L | P | . |
N | V | T | T | E | R | Y | Q | T | L | F | R | D | M | K | E | A | N | M | N | M | V | R | I | W | G | G | G | T | Y | E | N | N | L | F | Y | D | L | A |
Template Known Secondary structure |   |
|
|  |  |  |  |
|
|  |  | T | T |  |  |
|
|  |  |  |  | T | T |  |  |  |
|  |  |  |  |  |  |
|
| S |
| S | S | G | G | . | G |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|  |  |  |  |
| T | T | S |
|
|
|
|  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
| . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
331 | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | |
. | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . |
  |
  |   |
388 | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
Predicted Secondary structure |   |
 |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  | . | . | . | . | . | . | . | . | . | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Sequence |   |
D | I | Y | G | L | F | V | M | A | E | T | D | V | E | S | H | G | F | A | N | V | G | D | I | S | R | I | T | D | D | P | Q | W | E | K | V | Y | V | E | R | I | V | R | H | I | H | A | Q | K | N | H | P | S | I | I | I | W | S | L | G | N | E | S | G | Y | G | C | N | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Conservation |   |
|
|   |
|
|   |
|   |
|
|
|   |   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|
|
|
|
|
|
|
|   |
|
|
|
|
|
|
|
|   |
|   |   | . | . | . | . | . | . | . | . | . | . | . | . |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
|   |   |
|
|
|
|   |   |
|   |
|   |   |   |   |   | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |
|
|
|
|
|
|   |
|   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
D | E | N | G | I | L | V | W | Q | D | F | M | F | A | C | T | P | . |
. |
. |
. |
. |
. |
. |
. |
. |
Y | P | S | D | P | T | F | L | K | R | V | E | A | E | A | V | Y | N | I | R | R | L | R | N | H | A | S | L | A | M | W | C | G | N | N | E | I | L | E | A | L | K | Y | W | G | F | E | K | K | F | T | P | E | V |
Template Known Secondary structure |   |
 |  |  | T |
|  |  |  |  |  |
| S |
| B | S | S |
| . | . | . | . | . | . | . | . | . |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
| T | T |  |  |  |  |  | S |
| B | S |  |  |  |  |  |  |  | S |
| T | T | T | T | S |
|  |  |  |
Template Predicted Secondary structure |   |
 |  |
|
|
|  |  |  |  |  |
|  |  |
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
. | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 |
  |
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
456 | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | |
|
|
|
|
|
. | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
Query SS confidence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
I | R | A | M | Y | H | A | A | K | A | L | D | D | T | R | L | V | H | Y | E | E | D | . |
. |
. |
. |
. |
. |
R | D | A | E | V | V | D | I | I | S | T | M | Y | T | R | V | P | L | M | N | E | F | G | E | Y | P | H | P | K | P | R | I | I | C | E | Y | A | H | A | M |
Query Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |
|   |
|
|
|
|
|
|
|   |
|
|   |   | . | . | . | . | . | . |   |   |   |   |   |   |
|
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |   |
|
|   |
|
|
|
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|
|
|
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |
|   |   |   |
Template Sequence |   |
Y | Q | G | L | M | H | G | Y | D | K | L | F | R | E | L | L | P | S | T | V | K | E | F | D | S | D | R | F | Y | V | H | S | S | P | Y | L | A | N | W | G | R | P | E | S | W | G | T | G | D | S | H | N | W | G | V | W | Y | G | K | K | P | F | E | S | L | D | T | D | L | P | R | F | M | S | E | F | G | F | Q | S |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |  |  |
| T | T | S |  |  |  | S | S | B | S | S | S |
|
| T | T |
| G | G | G | T | T | B | S |
|  |  |
|
| T | T | T | T | T |
|
|
| G | G | G | G | G | T | S |
|
| S | S |  |  |  |
|
|
|
| B |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
481 | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 |
  |
  |   |
518 | . | 520 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | N | G | P | G | G | L | T | E | Y | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Q | N | V | F | Y | K | H | D | C | I | Q | G | H | Y | V | W | E | W | C | D | H | G | I | Q | A | Q | D | D | H | G |
Query Conservation |   |
|
|
|   |
|   |
|   |   |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|   |   |   |   |   |   |
|   |   |   |
|
|
|
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
F | P | E | M | K | T | I | A | A | F | A | A | P | E | D | Y | Q | I | E | S | E | V | M | N | A | H | Q | K | S | S | I | G | N | S | L | I | R | T | Y | M | E | R | D | Y | I | I | P | E | S | F | E | D | F | V | Y | V | G | L | V | L | Q | G | Q | G | M | R | H | G | L | E | A | H | R | R | N | R | P | Y | C | M |
Template Known Secondary structure |   |
|
|
|  |  |  |  |  |  |  |
|
| G | G | G |
| S | T | T | S |  |  |  |  |  | T | B |
| S | S | S |
| T |  |  |  |  |  |  |  |  |  |  | S |
|
|
| S | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | T | T |
|
|
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |
|
|  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
561 | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . | . | . | . | . | . | . | 610 | . | . | . | . | . | . | . | . | . | 620 | . | . | . | . | . | . | . | . | . | 630 | . | . | . | . | . | . | . | . | . | 640 |
  |
  |   |
558 | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600 | . |
Predicted Secondary structure |   |
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
N | V | W | Y | K | F | G | G | D | Y | G | D | Y | P | N | N | Y | N | F | C | L | D | G | L | I | Y | S | D | Q | T | P | G | P | G | L | K | E | Y | K | Q | V | I | A | P |
Query Conservation |   |
  |   |   |   |   |
|
|
|
|
|   |
|   |   |   |
|   |   |
|   |   |   |
|
|
|   |   |
|
|   |
|
|
|   |   |   |
|   |
|   |   |   |
|
|
Alig confidence |   |
. | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. | . | . | . | . | . |
|   |   |   |
|   |   |   |
|   |
|
|   |   |   |
|
|
|   |
|   |   |   |   |
|
|   |   |
|
|   |   |
|   |
|   |   |
|
Template Sequence |   |
. |
. |
. |
. |
. |
. |
G | T | L | Y | W | Q | L | N | D | S | W | P | V | V | S | W | S | S | I | D | Y | Y | G | N | W | K | A | L | H | Y | Q | A | K | R | A | F | A | P |
Template Known Secondary structure |   |
. | . | . | . | . | . |  |  |  |  | S |
| S |
|
| S | S | S |
| B | B | S |
| S | B |
| T | T | S |
| B |
|  |  |  |  |  |  |  |  |  | T |
|
|
Template Predicted Secondary structure |   |
. | . | . | . | . | . |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
|
641 | . | . | . | . | . | . | . | . | 650 | . | . | . | . | . | . | . | . | . | 660 | . | . | . | . | . | . | . | . | . | 670 | . | . | . | . | . | . | . | . |
  |