|   |
13 | . | . | |
. | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . |
Predicted Secondary structure |   |
|
|
| . |
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |
Query SS confidence |   |
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | P | V | . |
L | S | A | Q | E | A | V | N | Y | I | P | D | E | A | T | L | C | V | L | G | A | G | G | G | I | L | E | A | T | T | L | I | T | A | L | A | D | K | Y | K | Q | T | Q | T | P | R | N | L | S | I | I | S | P | T | G | L | G | D | R | A | D | R | G | I | S | P | L | A | Q | E | G | L | V | K | W | A |
Query Conservation |   |
  |
|
| . |
|
|
|   |
|
|
|   |   |
|   |
|
|   |
|
|   |   |   |
|
|   |   |   |   |   |   |
|   |   |
|   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |
|
|
|
|
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |
|   |
|   |
Alig confidence |   |
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|
|   |   |
|
|   |
|
|
|   |   |
|   |
|
|   |   |
|   |   |
|
|
|   |   |   | . |   |   |
|   |
|
|
|   |
|
|   |
| . | . | . | . | . |   |
|   |   |
|
|
|   |
|   |   |   |   |   |   |   | . | . |   |   |   |   |   |   |
|   |   |   |
|   |
|   |
|   |
Template Sequence |   |
T | K | F | Y | T | D | A | V | E | A | V | K | D | I | P | N | G | A | T | V | L | V | G | G | F | G | L | C | . |
G | I | P | E | N | L | I | G | A | L | L | K | . |
. |
. |
. |
. |
T | G | V | K | E | L | T | A | V | S | N | N | A | G | V | D | . |
. |
N | F | G | L | G | L | L | L | Q | S | K | Q | I | K | R | M |
Template Known Secondary structure |   |
|  |  |  | S |
|  |  |  |  |  | T | T |
|
| T | T |
|  |  |  |  |
|
| B | T | T | B | . | T |
|
|  |  |  |  |  |  |  |  |  | . | . | . | . | . |  |
|
|
| S |  |  |  |  |  | S | S |
|
| B | T | . | . | T | B | T |  |  |  |  |  |  | T | T |
|  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
| . |
|
|  |  |  |  |  |  |  |  |  |  | . | . | . | . | . |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
| . | . |
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
1 | . | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | |
. | 30 | . | . | . | . | . | . | . | . | . | 40 | |
|
|
|
|
. | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | |
|
. | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . |
  |
  |   |
92 | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | |
|
|
|
. | . | . | 160 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | C | G | H | W | G | Q | S | P | R | I | S | E | L | A | E | Q | N | K | I | I | A | Y | N | Y | P | Q | G | V | L | T | Q | T | L | R | A | A | A | A | H | Q | P | G | I | I | S | D | I | G | I | G | T | F | V | D | P | R | Q | Q | G | G | K | L | N | E | . |
. |
. |
. |
V | T | K | E | D | L | I | K | L | V | E |
Query Conservation |   |
  |   |   |   |   |
|   |   |
|   |   |
|   |   |
|   |   |
|   |
|
|   |   |   |   |   |   |
|   |   |   |   |   |
|
|
|   |
|   |
|   |
|   |   |   |
|   |   |   |
|
|
|   |
|   |   |
|   |   |
|
|   |   |   |   | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |   |   |
|   |   |
|   |   |   |   |   |
|   |   |
|   |
|
|   |   |   |   |   |   |
|   |
|   |   |   |
|
|
|   |
|   |
|   |
|   |   |   |
|   |   |
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
I | S | S | Y | V | G | E | N | A | E | F | E | R | Q | Y | L | A | G | E | L | E | V | E | L | T | P | Q | G | T | L | A | E | R | I | R | A | G | G | A | G | V | P | A | F | Y | T | S | T | G | Y | G | T | L | V | Q | E | G | G | S | P | I | K | Y | N | K | D | G | S | I | A | I | A | S | K | P | R | E | V | R | E |
Template Known Secondary structure |   |
 |  | S |
|
|
| S |
|  |  |  |  |  |  |  |  |  | T | S |
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|  |  |  |  | S | T | T | T | T | S |  |  |  |  |
|
|
|  |  |  |  |
| T | T | S |
|  |  |  |  |
|
|
|
|
|  |  |  |
Template Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |
|
|
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
73 | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . |
  |
  |   |
168 | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
F | D | N | K | E | Y | L | Y | Y | K | A | I | A | P | D | I | A | F | I | R | A | T | T | C | D | S | E | G | Y | A | T | F | E | D | E | V | M | Y | L | D | A | L | V | I | A | Q | A | V | H | N | N | G | G | I | V | M | M | Q | V | Q | K | M | V | K | K | A | T | L | H | P | K | S | V | R | I | P | G | Y | L | V |
Query Conservation |   |
  |   |
|   |   |   |
|   |   |   |
|
|   |   |
|
|
|
|
|   |   |
|   |
|
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |
|
|   |   |   |
|   |   |
|
|
|
|
|
|   |
|
|
|   |   |   |
|   |
|   |   |
|   |
|
|   |   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |   |   |
|   |   |   |
|
|   |   |
|
|
|
|
|   |
|   |   |
|
|   |   |
|
|
|   |   |   |
|   |   |   |   |   |   | . |   |   |   |
|   |
|
|   | . | . | . | . |   |
|
|
|   |
|
|   |
|
|   |   |   |   |
|   |
|   |   |
|   |
|
|
|   |   |
|
Template Sequence |   |
F | N | G | Q | H | F | I | L | E | E | A | I | R | G | D | F | A | L | V | K | A | W | K | A | D | Q | A | G | N | V | T | F | R | K | S | A | R | N | F | N | . |
L | P | M | C | K | A | A | E | . |
. |
. |
. |
T | T | V | V | E | V | E | E | I | V | D | I | G | S | F | A | P | E | D | I | H | I | P | K | I | Y | V |
Template Known Secondary structure |   |
 | T | T |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  | T | T | S |
|  |  |
|
| G | G | G |
| T | T |  | . |  |  |  | T | T | S |  |  | . | . | . | . |  |  |  |  |  |  |  |  |  |  |
| T | T | S | S |
| G | G | G |
| S | B |
| G | G | G |
|
Template Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
| . |  |  |  |  |  |  |
|
| . | . | . | . |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
153 | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | |
. | . | . | . | . | . | . | 200 | |
|
|
|
. | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . |
  |
  |   |
248 | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . |
Predicted Secondary structure |   |
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
D | I | V | V | V | D | P | D | Q | T | Q | L | Y | G | G |
Query Conservation |   |
|   |
|
|
|   |
|   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
H | R | L | V | K | G | E | K | Y | E | K | R | I | E | R |
Template Known Secondary structure |   |
|  |  |  |  |
| S |
|
|
|
|
|
|
|
|
Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
228 | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . |
  |