Return to main results Retrieve Phyre Job Id

Job DescriptionP39349
Confidence99.94%DateThu Jan 5 11:59:38 GMT 2012
Rank19Aligned Residues230
% Identity15%Templatec2xrgA_
PDB info PDB header:hydrolaseChain: A: PDB Molecule:ectonucleotide pyrophosphatase/phosphodiesterase family PDBTitle: crystal structure of autotaxin (enpp2) in complex with the2 ha155 boronic acid inhibitor
Resolution3.20 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   81........90.........100.........110.........120... ......130...... ...140.........150.......
Predicted Secondary structure 






















..






.











Query SS confidence 










































. .












.




















Query Sequence  TGKSSRXAPLYDTIVIVTGESVRRDYMSVYDYPVPTTPWLNTA. . PGLFIDDYTSTAS. STVSSLSRTLIYDYEQNPDSG
Query Conservation              


 
  

         
     

 
  
.. 
  
    
   . 
  
    


         
Alig confidence 






























...








..












.




















Template Conservation      



  

 









 


    ...  



  

  

      




 
 


 

 




  



Template Sequence  KVPECPAGFVRPPLIIFSVDGFRASYMKKGS. . . KVMPNIEKLRSCGTHAPYMRPVYPTKTFPNLYTLATGLYPESHGIV
Template Known Secondary structure 
S



TT
SS

T

GGGGGS
T...TTSS
S


SS
S
S
S

Template Predicted Secondary structure 


















...





















Template SS confidence 















































































   152.......160.........170.........180.. .......190.........200.........210.........220........
 
   158. 160.........170.........180.........190.........200.........
Predicted Secondary structure 

............................




































Query SS confidence 

. . . . . . . . . . . . . . . . . . . . . . . . . . . .

















































Query Sequence  NN. . . . . . . . . . . . . . . . . . . . . . . . . . . . VVALAAKAGYSTWWISNQGKLGEHDTRISVIASDAEHATFLKKGSFASRK
Query Conservation   
............................
   

  

 
                                      
Alig confidence 

............................












..............................






Template Conservation   
   
                      



 
    
 


..............................   



Template Sequence  GNSMYDPVFDASFHLRGREKFNHRWWGGQPLWITATKQGVRAG. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . TFFWSVS
Template Known Secondary structure 
SSTTTT
SSSSGGG
TTS

S

TTT

B
..............................




TT
Template Predicted Secondary structure 

























..............................



Template SS confidence 















































































   229230.........240.........250.........260.........270. .......
 
   210.........220.... .....230.........240.........250.........260.........270.........280.......
Predicted Secondary structure 

..




























Query SS confidence 














. .






























































Query Sequence  TDDKLLLQETERALA. . DTSSPKIIFLHMMGSHPNPCDSLNSXPNNYLEQYPRKIACYLASISKLDNFLGQLDGILRRYS
Query Conservation    
  
       
 ..    
 
        
 

                     
   
   
  
  

  
    
Alig confidence 














..



























............






















Template Conservation   
   


 
   
       
 

 

  


  

  

 
 
............   

  

  

 

  

  
Template Sequence  IPHERRILTILQWLSLPDNERPSVYAFYSEQPDFSGHKYGPFGPE. . . . . . . . . . . . MTNPLREIDKTVGQLMDGLKQLR
Template Known Secondary structure  S
TTS
TTT

S
TT
GG............GTT
Template Predicted Secondary structure 

















............

Template SS confidence 















































































   279280.........290.........300.........310.........320... ......330.........340......
 
   288.290.........
Predicted Secondary structure  ..





..................................................................
Query SS confidence  . .











. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Query Sequence  . . RHFAMLYFSGLG. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Query Conservation  ..  



  



..................................................................
Alig confidence  ..











..................................................................
Template Conservation 
 
 
 








  
     
 
              
    
  
     
   
          

 
  

 
 
Template Sequence  LHRCVNVIFVGDHGMEDVTCDRTEFLSNYLTNVDDITLVPGTLGRIRAKYDPKTIIAALTCKKPDQHFKPYMKQHLPKRL
Template Known Secondary structure 
TTT
S




SSSGGGT
S

TT
BS


TTSS
STT

GGGS
GGG
Template Predicted Secondary structure 






























Template SS confidence 















































































   347..350.........360.........370.........380.........390.........400.........410.........420......
 
   300.........310.........320.........330.........340.........350......
Predicted Secondary structure  ...................

































Query SS confidence  . . . . . . . . . . . . . . . . . . .
























































Query Sequence  . . . . . . . . . . . . . . . . . . . LSVSDSANPVHHYGHVQGGYSVPLIITASDITSHQPVSRKISARHFAGIFQWMTGIC
Query Conservation  ...................    
                




               
  
   
   
 

 
Alig confidence  ...................





































.

















Template Conservation 

    

 



    

        
 



     
 
 


 

 

 
    .

 








 



 
Template Sequence  HYANNRRIEDIHLLVDRRWHVARKPFQGDHGFDNKVNSMQTVFVGYGPTFKYRTKVP. PFENIELYNVMCDLLGLK
Template Known Secondary structure 


SSTTS
S
TT
S





S
TT
GGG
B
SSSB
SS
B

.
GGGT

Template Predicted Secondary structure 






































.






Template SS confidence 











































































   433......440.........450.........460.........470.........480......... 490.........500.......
 
Download:Text version FASTA pairwise alignment 3D Model in PDB format

View in Jmol

Send structure to FirstGlance for more viewing options


Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
Disclaimer
Terms and Conditions