|   |
19 | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | |
. | . | . | . | . | . | . | . | 50 | |
|
|
|
. | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | |
|
|
|
|
|
|
|
. | . | . | . | . | . | . | 80 | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  | . |
|
|
|
|  |  |  |  |  | . | . | . | . |  |  |
|
|
|
|  |  |  |  |  |
|
|  |  |  |
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|  |  |  |  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
S | R | R | K | L | D | E | L | D | L | I | V | V | D | H | P | Q | V | K | A | S | F | A | . |
L | Q | G | A | H | L | L | S | W | . |
. |
. |
. |
K | P | A | G | E | E | E | V | L | W | L | S | N | N | T | P | F | K | N | G | V | A | . |
. |
. |
. |
. |
. |
. |
. |
I | R | G | G | V | P | V | C | W | P | W | F | G |
Query Conservation |   |
  |   |   |   |   |   |   |
|   |   |
|   |
|   |   |   |   |   |   |
|   |
|   | . |   |   |
|
|   |
|   |
|   | . | . | . | . |   |   |   |   |   |   |
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . |
|
|
|
|
|
|   |   |   |
|   |
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |
|   |   |   |   |   |   |
|   |   |   |   |   |
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |
|
Template Sequence |   |
S | I | H | V | N | E | A | N | L | T | F | H | L | Q | T | D | H | T | S | Y | I | F | Q | I | X | K | N | G | E | A | G | Q | I | Y | Y | G | P | R | I | H | V | Q | P | T | Y | Q | N | L | X | S | Q | E | W | R | D | A | T | P | S | L | N | E | E | N | P | N | F | Q | P | A | T | I | K | A | E | Y | A | S | L | G |
Template Known Secondary structure |   |
|  |  |  |  | T | T | T | T |  |  |  |  |  |
| S | S |  |  |  |  |  |  |  |
| T | T | S | S |  |  |  |  |  |  |  |  |
|
|
|
|
| S |
|
| T | G | G | G |
|
|
|
|
| S | S | S |
|
| S |
| T | T |
| T | T |
|
| G | G | G | S |
| B | S | S |
|
| S | S |
Template Predicted Secondary structure |   |
|  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
2 | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . |
  |
  |   |
86 | . | . | . | 90 | . | |
|
|
|
. | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | |
Predicted Secondary structure |   |
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  | . |
Query SS confidence |   |
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
Query Sequence |   |
P | A | A | Q | Q | G | . |
. |
. |
. |
L | P | A | H | G | F | A | R | N | L | P | W | T | L | K | S | H | H | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
E | D | A | D | G | V | A | L | T | F | E | L | T | Q | S | E | E | T | K | K | F | W | P | H | D | F | T | L | L | A | H | F | R | V | . |
Query Conservation |   |
  |   |   |   |   |   | . | . | . | . |   |
|   |
|
|
|
|
|   |   |   |
|   |
|   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |
|   |   |   |   |   |
|   |
|   |
|   |   |   |   |   |
|   |   |   |   |
|   |   |
|   |
|   |   |   |
|   |
| . |
Alig confidence |   |
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
| . |
Template Conservation |   |
  |
|   |   |   |   |
|
|
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|   |
|   | . | . | . | . | . | . | . |   |   |   |
|   |
|   |
|   |
|   |   |   |
Template Sequence |   |
K | G | D | F | R | Q | P | A | F | Q | V | T | Q | A | N | G | S | R | I | T | E | L | T | Y | D | H | Y | Q | L | L | T | G | K | Q | R | L | A | N | L | P | S | T | F | D | D | T | D | D | D | A | Q | T | L | V | V | S | F | N | D | R | . |
. |
. |
. |
. |
. |
. |
I | T | G | L | A | L | D | L | N | Y | S | I | F |
Template Known Secondary structure |   |
S | S |
|
| S |
|
| S |  |  |  |  |
| T | T | S |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  | S |
|
|
|
| S | S | S |
|
|
|
|
|
| S |
|
|
|
|  |  |  |  |  |  |  |  |  | T | . | . | . | . | . | . | . | T | T |
|
|  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
| . | . | . | . | . | . | . |
|
|
|  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
82 | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | |
|
|
|
|
|
|
. | . | . | . | . | . | . | . | 150 | . | . | . | . |
  |
  |   |
|
|
|
|
|
|
144 | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
. | . | . | . | . | . |
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
Query SS confidence |   |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
. |
. |
. |
G | K | T | C | E | I | D | L | E | S | H | G | E | F | E | T | T | S | A | L | H | T | Y | F | N | V | G | D | I | A | K | V | S | V | S | G | L | G | D | R | F | I | D | K | V | N | D | A | K | E | N | V | L | T | D | G | I | Q | T | F | P | D | R | T | D | R | V | Y | L | N | P | Q | D | C |
Query Conservation |   |
. | . | . | . | . | . |   |   |   |
|   |
|   |
|   |   |   |   |   |   |
|
|   |   |
|   |
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|   |   |   |   |   |   |
Alig confidence |   |
. | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |
|
|   |   |   |   |   |
|   |
|   |
|   |   |   |
|   |
|   |   |   |   |
|   |   |
|   |   |
|   |   |   |   |   |
|   |   |   |   |
|   |
|   |   |
|   |   |   |   |   |   |   | . | . |
|   |   |
|   |   |   |   |   |
|   |   |
|   |
|
|
|   |   |   |
|   |
Template Sequence |   |
P | H | Q | D | V | I | V | K | S | A | K | F | T | N | P | S | S | E | K | L | V | L | N | R | A | L | S | S | Q | L | D | L | P | D | A | N | Y | D | L | I | Q | F | S | G | T | W | A | R | E | R | H | L | Y | R | H | P | . |
. |
L | R | P | G | X | Q | S | I | S | S | L | R | X | A | S | S | H | Q | Q | N | P | F |
Template Known Secondary structure |   |
G | G | G | T |  |  |  |  |  |  |  |  |  |
|
| S | S | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  | S |
|
|
|
|  |  |  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |  |  | . | . |
|
| S |  |  |  |  |  |  |
|
| S | S | S | S |
| S | S | B |
| S |
|
Template Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  | . | . |
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
155 | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | |
|
. | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . |
  |
  |   |
218 | . | 220 | . | . | . | . | . | . | . | |
|
|
|
|
|
. | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
| . | . | . | . | . | . |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |
|
|
|
|
|  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
S | V | I | N | D | E | A | L | N | R | . |
. |
. |
. |
. |
. |
I | I | A | V | G | H | Q | H | H | L | N | V | V | G | W | N | P | G | P | A | L | S | I | S | M | G | D | M | P | D | D | G | Y | K | T | F | V | C | V | E | T | A | Y | A | S | E | T | Q | K | V | T | K | E | K | P | A | H |
Query Conservation |   |
  |   |
|   |
|   |   |   |   |
| . | . | . | . | . | . |   |
|   |
|   |   |   |
|   |   |   |   |
|
|
|
|
|   |   |   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |
|
|
|
|
|
|   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |   |   |   |   |   |
|   |   |
|   |
|   |
|   |   |
|   |   |
|
|
|   |   |   |   |
|
|   | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |
|
|
|
|
|   |
Template Sequence |   |
X | X | L | A | R | P | Q | T | T | D | E | Q | G | A | V | F | G | F | N | L | V | Y | S | G | N | F | L | D | A | I | E | V | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
D | Q | Y | S | T | S | R | I | L | T | G | I | N | P | D | E | F | G | W | N | L | A | P | Q | A | T | F | Q |
Template Known Secondary structure |   |
 |  |  |  |
| T | T |
|
| S | S | S | B |
|  |  |  |  |  |  | S |
|
| S | S |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . |
| T | T | S |
|  |  |  |  |  |  |  |
| S | T | T |
|
|  |  |  |
| T | T |
|  |  |  |
Template Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |
|
|
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
233 | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . |
  |