|   |
229 | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | |
|
. | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
| . | . |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
S | P | Y | S | K | D | A | P | L | V | A | S | L | S | V | N | Q | K | I | T | G | R | N | S | E | K | D | V | R | H | I | E | I | D | L | G | D | S | G | M | . |
. |
R | Y | Q | P | G | D | A | L | G | V | W | Y | Q | N | D | P | A | L | V | K | E | L | V | E | L | L | W | L | K | G | D | E | P | V | T | V | E | G |
Query Conservation |   |
  |   |   |   |   |   |   |
|   |   |
|   |
|   |   |
|   |   |
|
|   |   |   |   |   |   |   |   |   |
|
|   |
|
|
|   |   |   |   |   | . | . |   |
|   |   |
|
|   |
|   |
|   |
|   |
|   |   |   |   |
|   |   |   |
|   |   |
|   |
|
|   |   |   |   |
|   |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
  |   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |
| . | . | . | . | . |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |
|   |
|   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Sequence |   |
T | T | P | Q | E | D | G | F | L | R | L | K | I | A | S | K | E | K | I | A | R | D | . |
. |
. |
. |
. |
I | W | S | F | E | L | T | D | P | Q | G | A | P | L | P | P | F | E | A | G | A | N | L | T | V | A | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
|
| T | T | T | T | T |
|  |  |  |  |  |  |  |  |  |  |  |  | T | T | . | . | . | . | . |  |  |  |  |  |  |  |
| T | T |
|
|
|
|
|
|
|
| T | T |
|  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
| . | . | . | . | . |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
1 | . | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | |
|
|
|
|
. | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |
  |   |
307 | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
K | T | L | P | L | N | E | A | L | Q | W | H | F | E | L | T | V | N | T | A | N | I | V | E | N | Y | A | T | L | T | R | S | E | T | L | L | P | L | V | G | D | K | A | K | L | Q | H | Y | A | A | T | T | P | I | V | D | M | V | R | F | S | P | A | Q | L | D | A | E | A | L | I | N | L | L | R | P | L | T | P | R |
Query Conservation |   |
  |   |   |   |
|   |   |   |
|   |   |   |   |
|
|   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |
|   |   |   |   |   |   |
|   |   |
|
|   |   |
|
|   |
|   |
|
|
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
Template Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |
|
Template Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
V | P | N | G | S | R | R |
Template Known Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
| T | T | S |
|  |  |
Template Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |
|
|
|
|  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
49 | 50 | . | . | . | . | . |
  |
  |   |
387 | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | Y | S | I | A | S | S | Q | A | E | V | E | N | E | V | H | V | T | V | G | V | V | R | Y | D | V | E | G | R | A | R | A | G | G | A | S | S | F | L | A | D | R | V | E | E | E | G | E | V | R | V | F | I | E | H | N | D | N | F | R | L | P | A | N | P | E | T | P | V | I | M | I | G | P | G | T | G | I | A | P |
Query Conservation |   |
  |
|
|
|
|
|
|
|   |   |   |   |   |   |
|   |
|
|
|   |   |
|   |   |   |   |   |   |   |   |
|   |
|   |   |
|   |   |
|   |   |   |
|   |   |
|   |   |
|   |
|   |   |   |   |   |   |   |
|   |
|
|   |   |   |   |   |
|
|
|
|
|
|   |
|
|
|
|
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|
|
|   |
|   |
|   | . |   |   |   |   |
|   |
|   |
|
|   |   | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   | . | . |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|   |
|
|
|
|
Template Sequence |   |
T | Y | S | L | C | N | D | S | Q | . |
E | R | N | R | Y | V | I | A | V | K | R | D | . |
. |
. |
. |
. |
. |
. |
S | N | G | R | G | G | S | I | S | F | I | D | D | T | S | E | G | D | A | V | E | V | S | . |
. |
L | P | R | N | E | F | P | L | D | K | R | A | K | S | F | I | L | V | A | G | G | I | G | I | T | P |
Template Known Secondary structure |   |
 |  |  |
|
| S |
| T | T | . |
|
| S |  |  |  |  |  |  |  |
|
| . | . | . | . | . | . | . | T | T | S |
| S |  |  |  |  |  |  |  | S |
|
| T | T |
|  |  |  |  |
| . | . |
|
| B |
|
| S |
|
|
| T | T |
| S |  |  |  |  |  |  |  | G | G | G |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
| . |
|
|
|  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
56 | . | . | . | 60 | . | . | . | . | |
. | . | . | . | . | 70 | . | . | . | . | . | . | |
|
|
|
|
|
|
. | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | |
|
100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . |
  |
  |   |
467 | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
F | R | A | F | M | Q | Q | R | A | A | D | E | A | P | G | K | N | W | L | F | F | G | N | P | H | F | T | E | D | F | L | Y | Q | V | E | W | Q | R | Y | V | K | D | G | V | L | T | R | I | D | L | A | W | S | R | D | Q | K | E | K | V | Y | V | Q | D | K | L | R | E | Q | G | A | E | L | W | R | W | I | N | D | G |
Query Conservation |   |
|
|
|
|
|
|   |
|   |   |   |   |   |   |
|   |   |   |
|
|
|
|   |
|   |   |   |   |
|   |
|
|   |   |
|
|   |   |   |   |   |   |
|   |
|   |   |
|   |   |
|
|
|
|
|   |   |   |
|   |
|
|
|
|   |
|   |   |   |   |   |   |
|   |   |   |
|   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
Template Conservation |   |
  |   |   |   |
|   |   |   |   |   |   |   | . |   |   |   |
|   |
|   |   |   |   |
|   |   |   | . |   |   |   |   |   |   |
|
|   |   |
|   |   |   |   |   |   | . |   |   |   |   |   |   |   |   | . |   |   |   |   |   |   |   |   |   |   |
|   |   |   | . | . | . | . | . | . | . | . |   |   |   |
Template Sequence |   |
M | L | S | M | A | R | Q | L | R | A | E | G | . |
L | R | S | F | R | L | Y | Y | L | T | R | D | P | E | . |
G | T | A | F | F | D | E | L | T | S | D | E | W | R | S | D | V | . |
K | I | H | H | D | H | G | D | . |
P | T | K | A | F | D | F | W | S | V | F | E | K | S | . |
. |
. |
. |
. |
. |
. |
. |
K | P | A |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |
| . | S | S |  |  |  |  |  |  |  |  | S |
| G | G | . | G |
| T | T |  |  |  |  |  | S | T | T | T | T | T | T |  | . |  |  |  |  |
| T | T |
| . | T | T | S |
|
|
|  |  |  |  |  | S | S |
| . | . | . | . | . | . | . | . |
| T | T |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
| . |
|
|
|  |  |  |  |  |  |
|
|
|  |  | . |  |  |  |
|  |  |  |  |  |  |  |  |  |
|
|
|  | . |  |  |  |  |  |
|
|
| . |
|
|
|
|
|
|  |  |  |  |  |  |
|
| . | . | . | . | . | . | . | . |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
126 | . | . | . | 130 | . | . | . | . | . | . | . | |
. | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | |
. | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | |
. | 170 | . | . | . | . | . | . | |
. | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | |
|
|
|
|
|
|
|
. | . | . |
  |
  |   |
547 | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | H | I | Y | V | C | G | D | A | N | R | M | A | K | D | V | E | Q | A | L |
Query Conservation |   |
|   |
|
|
|
|
|   |   |   |   |
|   |   |   |
|   |   |
|
|
Alig confidence |   |
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|
|
|
|
|
| . |   |   |
|   |   |   |
|   |   |   |
|
Template Sequence |   |
Q | H | V | Y | C | C | G | P | . |
Q | A | L | M | D | T | V | R | D | M | T |
Template Known Secondary structure |   |
 |  |  |  |  |  | S |
| . |  |  |  |  |  |  |  |  |  |  | T |
Template Predicted Secondary structure |   |
|  |  |  |  |
|
|
| . |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
194 | . | . | . | . | . | 200 | . | |
. | . | . | . | . | . | . | . | 210 | . | . |
  |