Job Description P31455 Confidence 99.88% Date Thu Jan 5 11:47:46 GMT 2012 Rank 30 Aligned Residues 374 % Identity 8% Template c2g5tA_ PDB info PDB header:hydrolase Chain: A: PDB Molecule:dipeptidyl peptidase 4; PDBTitle: crystal structure of human dipeptidyl peptidase iv (dppiv)2 complexed with cyanopyrrolidine (c5-pro-pro) inhibitor 21ag Resolution 2.30 Å

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		5	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.						.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.			.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.
Predicted Secondary structure																				.	.	.	.	.																										.	.
Query SS confidence																				.	.	.	.	.																										.	.
Query Sequence		V	L	Y	Q	D	R	A	M	K	Q	I	T	F	A	P	R	N	H	.	.	.	.	.	L	L	T	N	T	N	T	W	T	P	D	S	Q	W	L	V	F	D	V	R	P	S	G	A	S	.	.	F	T	G	E	T	I	E	R	V	N	I	H	T	G	E	V	E	V	I	Y	R	A	S	Q	G	A	H	V	G	V
Query Conservation																				.	.	.	.	.																										.	.
Alig confidence																				.	.	.	.	.																										.	.																								.	.
Template Conservation																																																																											.	.
Template Sequence		L	V	F	N	A	E	Y	G	N	S	S	V	F	L	E	N	S	T	F	D	E	F	G	H	S	I	N	D	Y	S	I	S	P	D	G	Q	F	I	L	L	E	Y	N	Y	V	K	Q	W	R	H	S	Y	T	A	S	Y	D	I	Y	D	L	N	K	R	Q	L	I	T	E	E	R	I	P	.	.	N	N	T	Q	W
Template Known Secondary structure						T	T	T									T	T	T	T	G	G	G	S	S							B		T	T	S	S												S	S	S											T	T	T	T					S	S				.	.	S	S	B
Template Predicted Secondary structure																																																																											.	.
Template SS confidence
		77	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.			150	.	.	.	.
		78	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.					.
Predicted Secondary structure																																																																													.	.	.	.
Query SS confidence																																																																													.	.	.	.
Query Sequence		V	T	V	H	P	K	S	E	K	Y	V	F	I	H	G	P	E	N	P	D	E	T	W	H	Y	D	F	H	H	R	R	G	V	I	V	E	G	G	K	M	S	N	L	D	A	M	D	I	T	A	P	Y	T	P	G	V	L	R	G	G	S	H	V	H	V	F	S	P	N	G	E	R	V	S	F	.	.	.	.	T
Query Conservation																																																																													.	.	.	.
Alig confidence																		.	.	.	.																																																								.	.	.	.
Template Conservation																		.	.	.	.
Template Sequence		V	T	W	S	P	V	G	H	K	L	A	Y	V	W	N	N	.	.	.	.	D	I	Y	V	K	I	E	P	N	L	P	S	Y	R	I	T	W	T	G	K	E	D	I	I	Y	N	G	I	T	D	W	V	Y	E	E	E	V	F	S	A	Y	S	A	L	W	W	S	P	N	G	T	F	L	A	Y	A	Q	F	N	D
Template Known Secondary structure						S	S	S	S							T	T	.	.	.	.						S	S	T	T	S							S			B	T	T	T				S	B									T	S	S	S	S	B						T	T	S	S
Template Predicted Secondary structure																		.	.	.	.
Template SS confidence
		155	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170					.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230
		154	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		Y	N	D	H	V	M	H	E	L	D	P	A	L	D	L	R	N	V	G	V	A	A	P	F	G	P	V	N	V	Q	K	Q	H	P	R	E	Y	S	G	S	H	W	C	V	L	V	S	K	T	T	P	T	P	Q	P	G	S	D	E	I	N	R	A	Y	E	E	G	W	V	G	N	H	A	L	A	F	I	G	D	T
Query Conservation
Alig confidence																							.	.	.	.	.	.
Template Conservation																							.	.	.	.	.	.
Template Sequence		T	E	V	P	L	I	E	Y	S	F	Y	S	D	E	S	L	Q	Y	P	K	T	.	.	.	.	.	.	V	R	V	P	Y	P	K	A	G	A	V	N	P	T	V	K	F	F	V	V	N	T	D	S	L	S	S	V	T	N	A	T	S	I	Q	I	T	A	P	A	S	M	L	I	G	D	H	Y	L	C	D	V	T
Template Known Secondary structure		T	T											S	T	T		S	S				.	.	.	.	.	.							B	T	T	S												T	T	S			S	S	S															T	S
Template Predicted Secondary structure																							.	.	.	.	.	.
Template SS confidence
		231	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.							.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.
		234	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.						.	.	300	.	.	.	.	.	.	.	.
Predicted Secondary structure																																																																		.	.	.	.	.
Query SS confidence																																																																		.	.	.	.	.
Query Sequence		L	S	P	K	G	E	K	V	P	E	L	F	I	V	E	L	P	Q	D	E	A	G	W	K	A	A	G	D	A	P	L	S	G	T	E	T	T	L	P	A	P	P	R	G	V	V	Q	R	R	L	T	F	T	H	H	R	A	Y	P	G	L	V	N	V	.	.	.	.	.	P	R	H	W	V	R	C	N	P	Q	G
Query Conservation																																																																		.	.	.	.	.
Alig confidence														.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																																					.	.	.	.	.
Template Conservation														.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		W	A	T	Q	E	R	I	S	L	Q	W	L	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	R	R	I	Q	N	Y	S	V	M	D	I	C	D	Y	D	E	S	S	G	R	W	N	C	L	V	A	R	Q	H	I	E	M	S	T	T	G	W	V	G	R	F	R	P	S	E	P	H	F	T	L	D	G
Template Known Secondary structure				S	S	S								.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.		S	S	T	T											G	G	G	T						T	T	S							S	S	S		S	S	S	S	S								T	T	S
Template Predicted Secondary structure														.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		305	.	.	.	.	310	.	.	.	.	.	.																	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.
		309	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.							.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.
Predicted Secondary structure																																																							.	.	.	.	.	.
Query SS confidence																																																							.	.	.	.	.	.
Query Sequence		T	Q	I	A	F	L	M	R	D	D	N	G	I	V	Q	L	W	L	I	S	P	Q	G	G	E	P	R	Q	L	T	H	N	K	T	D	I	Q	S	A	F	N	W	H	P	S	G	E	W	L	G	F	V	L	.	.	.	.	.	.	D	N	R	I	A	C	A	H	A	Q	S	G	E	V	E	Y	L	T	E	H	H
Query Conservation																																																							.	.	.	.	.	.
Alig confidence																																																							.	.	.	.	.	.
Template Conservation
Template Sequence		N	S	F	Y	K	I	I	S	N	E	E	G	Y	R	H	I	C	Y	F	Q	I	D	K	K	D	C	T	F	I	T	K	G	T	W	E	V	I	G	I	E	A	L	T	S	D	Y	L	Y	Y	I	S	N	E	Y	K	G	M	P	G	G	R	N	L	Y	K	I	Q	L	S	D	Y	T	K	V	T	C	L	S	C	E
Template Known Secondary structure		S									T	T	S									T	T		S	S				S			S	S	S										S	S							S		G	G	G		T	T		B							T	T		T	T					S	S	T	T
Template Predicted Secondary structure
Template SS confidence
		369	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.
				383	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.
Predicted Secondary structure		.	.
Query SS confidence		.	.
Query Sequence		.	.	A	N	S	P	S	A	D	A	V	V	F	S	P	D	G	Q	W	L	A	W	M	E	G	G
Query Conservation		.	.
Alig confidence		.	.
Template Conservation
Template Sequence		L	N	P	E	R	C	Q	Y	Y	S	V	S	F	S	K	E	A	K	Y	Y	Q	L	R	C	S	G
Template Known Secondary structure		T		T	T	T	B		B							T	T	S	S								S
Template Predicted Secondary structure
Template SS confidence
		449	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions