|   |
137 | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 |
Predicted Secondary structure |   |
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | S | H | V | H | V | F | S | P | N | G | E | R | V | S | F | T | Y | N | D | H | V | M | H | E | L | D | P | A | L | D | L | R | N | V | G | V | A | A | P | F | G | P | V | N | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
V | Q | K | Q | H | P | R | E | Y | S | G | S | H | W | C | V | L | V | S |
Query Conservation |   |
  |   |   |   |   |   |   |
|
|
|
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |   |
|
|
|
|   |   |
|   |   |   |   |
|
|   |   |
|
|   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
Template Sequence |   |
A | P | N | S | F | T | F | D | S | T | N | K | G | F | Y | T | S | V | Q | D | G | R | V | I | K | Y | E | G | P | N | S | G | F | V | D | F | A | Y | A | S | P | Y | W | N | K | A | F | C | E | N | S | T | D | A | E | K | R | P | L | C | G | R | T | Y | D | I | S | Y | N | L | Q | N | N | Q | L | Y | I | V | D | C |
Template Known Secondary structure |   |
|
|
|
|  |  |
|
| T | T |
| S | S |  |  |  |  |
| T | T | S |  |  |  |  |  |
|
| T | T | T |
|  |  |  |  |  |  | S |
| T | T |
|
|  |  |  |  | T | T |
|
|
| G | G | G |  |  |  |  |
|
|  |  |  |  |  |  |  | T | T | T | T |  |  |  |  |  |  | T |
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
42 | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . |
  |
  |   |
201 | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 |
Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
K | T | T | P | T | P | Q | P | G | S | D | E | I | N | R | A | Y | E | E | G | W | V | G | N | H | A | L | A | F | I | G | D | T | L | S | P | K | G | E | K | V | P | E | L | F | I | V | E | L | P | Q | D | E | A | G | W | K | A | A | G | D | A | P | L | S | G | T | E | T | T | L | P | A | P | P | R | G | V | V | Q |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . |
Template Sequence |   |
Y | Y | H | L | S | V | V | G | S | E | G | G | H | A | T | Q | L | A | T | S | V | D | G | V | P | F | K | W | L | Y | A | V | T | V | D | Q | R | T | G | I | V | Y | F | T | D | V | S | T | L | Y | D | D | R | G | V | Q | Q | I | M | D | T | S | D | K | T | G | R | L | I | K | Y | D | P | . |
. |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
T | T |  |  |  |  |  |
| T | T |
|  |  |
|  |  |  |  | S |  |  | T | T |  |  |
| S |
|  |  |  |  |  |  |
| T | T | T |
|
|  |  |  |  |  | S |
| S | S |
|
| T | T |
|  |  |  |  |  |  |  | T |
|
|
|  |  |  |  |  |  |  | T | . | . | . | . | . | . | . |
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
| . | . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
122 | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | |
|
|
|
|
|
|
  |
  |   |
281 | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 |
Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
R | R | L | T | F | T | H | H | R | A | Y | P | G | L | V | N | V | P | R | H | W | V | R | C | N | P | Q | G | T | Q | I | A | F | L | M | R | D | D | N | G | I | V | Q | L | W | L | I | S | P | Q | G | G | E | P | R | Q | L | T | H | N | K | T | D | I | Q | S | A | F | N | W | H | P | S | G | E | W | L | G | F | V |
Query Conservation |   |
  |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|
|   |   |
|
|   |   |
Alig confidence |   |
. | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
| . | . |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
Template Sequence |   |
. |
. |
. |
. |
S | T | K | E | T | T | L | L | L | K | E | L | H | V | P | G | G | A | E | V | S | A | D | S | S | F | V | L | V | A | E | F | L | S | H | Q | I | V | K | Y | W | . |
. |
L | E | G | P | K | K | G | T | A | E | V | L | V | K | I | P | N | P | G | N | I | K | R | N | A | D | G | H | F | W | V | S | S |
Template Known Secondary structure |   |
. | . | . | . | T | T | T |  |  |  |  |  |  |  |  |  | S |
|
|
|  |  |  |  |
| T | T | S | S |  |  |  |  |  |  | G | G | G | T |  |  |  |  |  |  | . | . | S | S | S | T | T | T | T |
|  |  |  |  |  |  |
| S | S |  |  |  |  |  |  |
| T | T | S |
|  |  |  |  |  |
Template Predicted Secondary structure |   |
. | . | . | . |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  | . | . |
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
195 | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | |
|
. | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . |
  |
  |   |
361 | |
. | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | |
|
|
|
|
. | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . |
Predicted Secondary structure |   |
 | . |
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
| . | . | . | . | . |  |  |  |  |  |  |
|
|  |  |  |  |  |  |
|
|
Query SS confidence |   |
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | . |
D | N | R | I | A | C | A | H | A | Q | S | G | E | V | E | Y | L | T | E | H | H | A | N | S | P | S | A | D | A | V | V | F | S | P | D | G | Q | . |
. |
. |
. |
. |
W | L | A | W | M | E | G | G | Q | L | W | I | T | E | T | D |
Query Conservation |   |
| . |
|   |   |
|   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|   | . | . | . | . | . |   |
|
|   |   |   |   |
|   |   |   |   |   |   |   |
|
Alig confidence |   |
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . |   |   |   |
|   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |
|   |
|   |   |   |   |
|   |
|   |
|
|
|   |   |
Template Sequence |   |
S | E | E | L | D | G | N | M | H | G | R | V | D | P | K | G | I | K | F | . |
. |
. |
. |
D | E | F | G | N | I | L | E | V | I | P | L | P | P | P | F | A | G | E | H | F | E | Q | I | Q | E | H | D | G | L | L | Y | I | G | T | L | F |
Template Known Secondary structure |   |
 |  |  | T | T | S | S | T | T | S |
|  |  |  |  |  |  |  |  | . | . | . | . |
| T | T | S |
|  |  |  |  |  |  |
|
| T | T | T | T | T | S |
|
|
|  |  |  |  |  | T | T |  |  |  |  |  |
| S | S |
Template Predicted Secondary structure |   |
|
|
|
|
|  |  |  |
|
|
|
|
|
|  |  |  |  |  | . | . | . | . |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
269 | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | |
|
|
|
. | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . |
  |