Job Description P30177 Confidence 100.00% Date Thu Jan 5 11:46:14 GMT 2012 Rank 10 Aligned Residues 292 % Identity 18% Template c2j0fC_ PDB info PDB header:transferase Chain: C: PDB Molecule:thymidine phosphorylase; PDBTitle: structural basis for non-competitive product inhibition in2 human thymidine phosphorylase: implication for drug design Resolution 2.31 Å

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		2	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.				.	.
Predicted Secondary structure																																																																													.	.	.
Query SS confidence																																																																													.	.	.
Query Sequence		D	Y	R	K	I	I	K	E	I	G	R	G	K	N	H	A	R	D	L	D	R	D	T	A	R	G	L	Y	A	H	M	L	N	G	E	V	P	D	L	E	L	G	G	V	L	I	A	L	R	I	K	G	E	G	E	A	E	M	L	G	F	Y	E	A	M	Q	N	H	T	I	K	L	T	P	P	.	.	.	A	G
Query Conservation																																																																													.	.	.
Alig confidence										.	.	.	.																																																																.	.	.
Template Conservation										.	.	.	.
Template Sequence		Q	L	P	E	L	I	R	M	.	.	.	.	K	R	D	G	G	R	L	S	E	A	D	I	R	G	F	V	A	A	V	V	N	G	S	A	Q	G	A	Q	I	G	A	M	L	M	A	I	R	L	R	G	M	D	L	E	E	T	S	V	L	T	Q	A	L	A	Q	S	G	Q	Q	L	E	W	P	E	A	W	R	Q
Template Known Secondary structure										.	.	.	.			T	T																		T		S																															T	T	S							G	G	G	T	T
Template Predicted Secondary structure										.	.	.	.
Template SS confidence
		35	.	.	.	.	40	.	.					.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110
		79	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.		.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.
Predicted Secondary structure																																																									.																								.
Query SS confidence																																																									.																								.
Query Sequence		K	P	M	P	I	V	I	P	S	Y	N	G	A	R	K	Q	A	N	L	T	P	L	L	A	I	L	L	H	K	L	G	F	P	V	V	V	H	G	V	S	E	D	P	T	R	V	L	T	E	T	I	F	E	L	M	.	G	I	T	P	T	L	H	G	G	Q	A	Q	A	K	L	D	E	H	Q	P	V	F	M	.
Query Conservation																																																									.																								.
Alig confidence														.	.	.	.																																								.																								.
Template Conservation														.	.	.	.
Template Sequence		Q	L	V	D	K	H	S	T	G	G	V	G	.	.	.	.	D	K	V	S	L	V	L	A	P	A	L	A	A	C	G	C	K	V	P	M	I	S	G	R	G	L	G	H	T	G	G	T	L	D	K	L	E	S	I	P	G	F	N	V	I	Q	S	P	E	Q	M	Q	V	L	L	D	Q	A	G	C	C	I	V	G
Template Known Secondary structure		T	B						S			T	T	.	.	.	.														T	T		B									B	T	T	B								T	T	S	T	T																	T	S
Template Predicted Secondary structure														.	.	.	.
Template SS confidence
		111	.	.	.	.	.	.	.	.	120	.	.					.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.
		157	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.		220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.
Predicted Secondary structure																																																																	.
Query SS confidence																																																																	.
Query Sequence		P	V	G	A	F	C	P	P	L	E	K	Q	L	A	M	R	W	R	M	G	V	R	N	S	A	H	T	L	A	K	L	A	T	P	F	A	E	G	E	A	L	R	L	S	S	V	S	H	P	E	Y	I	G	R	V	A	K	F	F	S	D	I	G	.	G	R	A	L	L	M	H	G	T	E	G	E	V	Y	A	N
Query Conservation																																																																	.
Alig confidence																						.	.						.	.						.	.	.	.	.	.	.	.	.	.																				.
Template Conservation																						.	.						.	.						.	.	.	.	.	.	.	.	.	.
Template Sequence		Q	S	E	Q	L	V	P	A	D	G	I	L	Y	A	A	R	D	V	T	A	.	.	T	V	D	S	L	.	.	P	L	I	T	A	.	.	.	.	.	.	.	.	.	.	S	I	L	S	K	K	L	V	E	G	L	S	A	L	V	V	D	V	K	F	G	A	G	A	V	F	P	N	Q	E	Q	A	R	E	L	A
Template Known Secondary structure				S	S	S													T	T	T	.	.		S	S			.	.						.	.	.	.	.	.	.	.	.	.									T	T		S									S	T	T	S	S	S		S
Template Predicted Secondary structure																						.	.						.	.						.	.	.	.	.	.	.	.	.	.
Template SS confidence
		187	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.			.	.	.	210	.			.	.	.	.	.											.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.
		236	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.			.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.
Predicted Secondary structure																																																					.	.
Query SS confidence																																																					.	.
Query Sequence		P	Q	R	C	P	Q	I	N	L	I	D	R	E	G	M	R	V	L	Y	E	K	Q	D	T	A	G	S	E	L	L	P	Q	A	K	D	P	E	T	T	A	Q	W	I	E	R	C	L	A	G	S	E	.	.	P	I	P	E	S	L	K	I	Q	M	A	C	C	L	V	A	T	G	E	A	A	T	I	S	D	G	L
Query Conservation																																																					.	.
Alig confidence										.	.																			.	.	.																					.	.
Template Conservation										.	.																			.	.	.
Template Sequence		K	T	L	V	G	V	G	A	.	.	S	L	G	L	R	V	A	A	A	L	T	A	M	D	K	P	L	G	.	.	.	R	C	V	G	H	A	L	E	V	E	E	A	L	L	C	M	D	G	A	G	P	P	D	L	R	D	L	V	T	T	L	G	G	A	L	L	W	L	S	G	H	A	G	T	Q	A	Q	G	A
Template Known Secondary structure										.	.		T	T											S	S		S	S	.	.	.	S				S												T	T		S																			T	T	S	S	S	S
Template Predicted Secondary structure										.	.																			.	.	.
Template SS confidence
		253	.	.	.	.	.	.	260			.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.				.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.
		314	.	.	.	.	.	320
Predicted Secondary structure
Query SS confidence
Query Sequence		A	R	V	N	Q	A	F
Query Conservation
Alig confidence
Template Conservation
Template Sequence		A	R	V	A	A	A	L
Template Known Secondary structure
Template Predicted Secondary structure
Template SS confidence
		328	.	330	.	.	.	.

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Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
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