Job Description P21165 Confidence 100.00% Date Thu Jan 5 11:37:53 GMT 2012 Rank 1 Aligned Residues 424 % Identity 51% Template c3l24A_ PDB info PDB header:hydrolase Chain: A: PDB Molecule:xaa-pro dipeptidase; PDBTitle: crystal structure of the nerve agent degrading2 organophosphate anhydrolase/prolidase in complex with3 inhibitors Resolution 2.30 Å

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		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80
Predicted Secondary structure
Query SS confidence
Query Sequence		M	E	S	L	A	S	L	Y	K	N	H	I	A	T	L	Q	E	R	T	R	D	A	L	A	R	F	K	L	D	A	L	L	I	H	S	G	E	L	F	N	V	F	L	D	D	H	P	Y	P	F	K	V	N	P	Q	F	K	A	W	V	P	V	T	Q	V	P	N	C	W	L	L	V	D	G	V	N	K	P	K	L
Query Conservation
Alig confidence
Template Conservation
Template Sequence		M	N	K	L	A	V	L	Y	A	E	H	I	A	T	L	Q	K	R	T	R	E	I	I	E	R	E	N	L	D	G	V	V	F	H	S	G	Q	A	K	R	Q	F	L	D	D	M	Y	Y	P	F	K	V	N	P	Q	F	K	A	W	L	P	V	I	D	N	P	H	C	W	I	V	A	N	G	T	D	K	P	K	L
Template Known Secondary structure																											T	T		S											B		T	T	S	S		B											T	T	S	S			S		S	S							S	S	S
Template Predicted Secondary structure
Template SS confidence
		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80
		81	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160
Predicted Secondary structure
Query SS confidence
Query Sequence		W	F	Y	L	P	V	D	Y	W	H	N	V	E	P	L	P	T	S	F	W	T	E	D	V	E	V	I	A	L	P	K	A	D	G	I	G	S	L	L	P	A	A	R	G	N	I	G	Y	I	G	P	V	P	E	R	A	L	Q	L	G	I	E	A	S	N	I	N	P	K	G	V	I	D	Y	L	H	Y	Y	R	S
Query Conservation
Alig confidence																																																															.	.
Template Conservation																																																															.	.
Template Sequence		I	F	Y	R	P	V	D	F	W	H	K	V	P	D	E	P	N	E	Y	W	A	D	Y	F	D	I	E	L	L	V	K	P	D	Q	V	E	K	L	L	P	Y	D	K	A	R	F	A	Y	I	G	E	Y	L	E	V	A	Q	A	L	G	F	.	.	E	L	M	N	P	E	P	V	M	N	F	Y	H	Y	H	R	A
Template Known Secondary structure									S	S	S								S	G	G	G	G	G	S						S	S	G	G	G		G	G	G	S		S			T	T					S	S									T		.	.			B	S													T
Template Predicted Secondary structure																																																															.	.
Template SS confidence
		81	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.			.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.
		161	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Predicted Secondary structure
Query SS confidence
Query Sequence		F	K	T	E	Y	E	L	A	C	M	R	E	A	Q	K	M	A	V	N	G	H	R	A	A	E	E	A	F	R	S	G	M	S	E	F	D	I	N	I	A	Y	L	T	A	T	G	H	R	D	T	D	V	P	Y	S	N	I	V	A	L	N	E	H	A	A	V	L	H	Y	T	K	L	D	H	Q	A	P	E	E	M
Query Conservation
Alig confidence
Template Conservation
Template Sequence		Y	K	T	Q	Y	E	L	A	C	M	R	E	A	N	K	I	A	V	Q	G	H	K	A	A	R	D	A	F	F	Q	G	K	S	E	F	E	I	Q	Q	A	Y	L	L	A	T	Q	H	S	E	N	D	N	P	Y	G	N	I	V	A	L	N	E	N	C	A	I	L	H	Y	T	H	F	D	R	V	A	P	A	T	H
Template Known Secondary structure		S																													T	T															T			G	G	G	S	S	S							G	G	G	G	G		T	T						S	S			S	S
Template Predicted Secondary structure
Template SS confidence
		159	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.
		241	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320
Predicted Secondary structure
Query SS confidence
Query Sequence		R	S	F	L	L	D	A	G	A	E	Y	N	G	Y	A	A	D	L	T	R	T	W	S	A	K	S	D	N	D	Y	A	Q	L	V	K	D	V	N	D	E	Q	L	A	L	I	A	T	M	K	A	G	V	S	Y	V	D	Y	H	I	Q	F	H	Q	R	I	A	K	L	L	R	K	H	Q	I	I	T	D	M	S	E
Query Conservation
Alig confidence																																																																																.
Template Conservation																																																																																.
Template Sequence		R	S	F	L	I	D	A	G	A	N	F	N	G	Y	A	A	D	I	T	R	T	Y	D	F	T	G	E	G	E	F	A	E	L	V	A	T	M	K	Q	H	Q	I	A	L	M	N	Q	L	A	P	G	K	L	Y	G	E	L	H	L	D	C	H	Q	R	V	A	Q	T	L	S	D	F	N	I	V	D	L	S	.	A
Template Known Secondary structure													T	T											S	S	S		S																		T	T			T	T		B																			T	T	S	B	S	S		.
Template Predicted Secondary structure																																																																																.
Template SS confidence
		239	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.		.
		321	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400
Predicted Secondary structure
Query SS confidence
Query Sequence		E	A	M	V	E	N	D	L	T	G	P	F	M	P	H	G	I	G	H	P	L	G	L	Q	V	H	D	V	A	G	F	M	Q	D	D	S	G	T	H	L	A	A	P	A	K	Y	P	Y	L	R	C	T	R	I	L	Q	P	G	M	V	L	T	I	E	P	G	I	Y	F	I	E	S	L	L	A	P	W	R	E	G
Query Conservation
Alig confidence																																					.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																																					.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		D	E	I	V	A	K	G	I	T	S	T	F	F	P	H	G	L	G	H	H	I	G	L	Q	V	H	D	V	G	G	F	M	A	L	R	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	C	T	R	K	I	E	A	N	Q	V	F	T	I	E	P	G	L	Y	F	I	D	S	L	L	G	D	L	A	A	T
Template Known Secondary structure							T	T		G	G	G	T			S		S			B		S	S	S	S	S					T	T				.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	T	T		B			T	T																					T	S
Template Predicted Secondary structure																																					.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		318	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.																.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.
		401	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		Q	F	S	K	H	F	N	W	Q	K	I	E	A	L	K	P	F	G	G	I	R	I	E	D	N	V	V	I	H	E	N	N	V	E	N	M	T	R	D	L	K	L
Query Conservation
Alig confidence
Template Conservation
Template Sequence		D	N	N	Q	H	I	N	W	D	K	V	A	E	L	K	P	F	G	G	I	R	I	E	D	N	I	I	V	H	E	D	S	L	E	N	M	T	R	E	L	R	L
Template Known Secondary structure		G	G	G	G	G	B									G	G	G						B							S	S									T	T
Template Predicted Secondary structure
Template SS confidence
		398	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.