|   |
1 | . | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | |
|
. | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
| . | . |
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
M | K | I | L | V | T | G | G | A | G | F | I | G | S | A | V | V | R | H | I | I | N | N | T | Q | D | S | V | V | N | V | D | K | L | T | Y | A | G | N | R | E | S | L | A | D | V | S | . |
. |
D | S | E | R | Y | V | F | E | H | A | D | I | C | D | A | P | A | M | A | R | I | F | A | Q | H | Q | P | D | A | V | M |
Query Conservation |   |
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
|
|   |   |
|
|   |   |
|   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . |   |   |   |   |
|   |   |
|   |   |
|
|   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|
|
|
|
|
|
|
|
|   |
|
|   |   |
|   |   |   |
|   |   |   |
|   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |
Template Sequence |   |
S | R | I | L | L | I | G | A | T | G | Y | I | G | R | H | V | A | K | A | S | L | D | L | G | H | P | T | F | L | L | V | R | E | S | T | A | S | S | N | S | E | K | A | Q | L | L | E | S | F | K | A | S | G | A | N | I | V | H | G | S | I | D | D | H | A | S | L | V | E | A | V | K | N | V | D | V | V | I | S | T |
Template Known Secondary structure |   |
|
|  |  |  |  | S | T | T | S | T | T |  |  |  |  |  |  |  |  |  |  | T | T |
|
|  |  |  |  |
|
|
|
|
| T | T | T | T |  |  |  |  |  |  |  |  |  |  |  | T | T | T |
|  |  |  |
|
|
| T | T |
|  |  |  |  |  |  |  |  |  | T |
| S |  |  |  |  |
|
Template Predicted Secondary structure |   |
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
5 | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . |
  |
  |   |
79 | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
H | L | A | A | E | S | H | V | D | R | S | I | T | G | P | A | A | F | I | E | T | N | I | V | G | T | Y | V | L | L | E | A | A | R | N | Y | W | S | A | L | D | S | D | K | K | N | S | F | R | F | H | H | I | S | T | D | E | V | Y | G | D | L | P | H | P | D | E | V | N | N | T | E | E | L | P | L | F | T | E | T |
Query Conservation |   |
  |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
  |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |
|   |   |   | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Sequence |   |
V | G | S | L | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Q | I | E | S | Q | V | N | I | I | K | A | I | K | E | . |
. |
. |
. |
. |
. |
. |
. |
. |
V | G | T | V | K | R | F | F | P | S | E | F | G | N | D | V | D | N | V | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
|
| G | G | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | G | S | G | G | G |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . |  |
|
|
| S |  |  |  |
| S |
|
| S | S |
| T | T | S |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Predicted Secondary structure |   |
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
85 | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | |
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |
  |   |
159 | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
T | A | Y | A | P | S | S | P | Y | S | A | S | K | A | S | S | D | H | L | V | R | A | W | K | R | T | Y | G | L | P | T | I | V | T | N | C | S | N | N | Y | G | P | Y | H | F | P | E | K | L | I | P | L | V | I | L | N | A | L | E | G | K | A | L | P | I | Y | G | K | G | D | Q | I | R | D | W | L | Y | V | E | D |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
Template Sequence |   |
H | A | V | E | P | A | K | S | V | F | E | V | K | A | K | V | R | R | A | I | E | A | E | G | I | P | Y | T | Y | V | S | S | N | C | F | A | G | Y | F | L | R | S | L | A | Q | A | G | L | T | . |
. |
. |
. |
. |
. |
. |
A | P | P | R | D | K | V | V | I | L | G | D | G | N | A | R | V | V | F | V | K | E | E | D |
Template Known Secondary structure |   |
|
|
| T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
| B |  |  |  |  |
|
|  |  |  |  |  |  | T | T | T | T | T |
| T | T |
| S | . | . | . | . | . | . | . | S |
|
| S | S |  |  |  |  |  | T | T | S |
|
|  |  |  |  |  |
|  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  | . | . | . | . | . | . | . |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
122 | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | |
|
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . |
  |
  |   |
239 | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | |
|
. | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
| . | . |
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
Query Sequence |   |
H | A | R | A | L | Y | T | V | V | T | E | G | K | A | G | E | . |
. |
T | Y | N | I | G | G | H | N | E | K | K | N | I | D | V | V | L | T | I | C | D | L | L | D | E | I | V | P | K | E | K | S | Y | R | E | Q | I | T | Y | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
V | A | D |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . |   |   |   |
|   |   |   |   |   |   |
|   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
Template Conservation |   |
  |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
I | G | T | F | T | I | K | A | V | D | D | P | R | T | L | N | K | T | L | Y | L | R | L | P | A | N | T | L | S | L | N | E | L | V | A | L | W | E | K | K | I | D | K | T | L | E | K | A | Y | V | P | E | E | E | V | L | K | L | I | A | D | T | P | F | P | A | N | I | S | I | A | I | S | H | S | I | F | V | K | G |
Template Known Secondary structure |   |
 |  |  |  |  |  | T | T | S | S |
| G | G | G | T | T |  |  |  |  |
|
|
| G | G | G |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | S |
|
|  |  |  |  |  |
|  |  |  |  |  |  |  |  |  | T | S |
| T | T |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
195 | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . |
  |
  |   |
297 | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . |
Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |  |
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
R | P | G | H | D | R | R | Y | A | I | D | A | E | K | I | G | R | A | L | G | W | K | P | Q | E | T | F | E | S | G | I | R | K | T | V |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |   |
|
|   |   |
|   |   |   |
|   |
|   |
|   |   |
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   | . |
|   |
|
|   |
|   |   |   |
|
Template Sequence |   |
D | Q | T | N | F | E | I | G | P | A | G | V | E | A | S | Q | L | Y | P | D | V | K | Y | T | . |
T | V | D | E | Y | L | S | N | F | V |
Template Known Secondary structure |   |
T | T | T | S | S |
|
|
| T | T |  |  |  |  |  |  |  |
| T | T |
|
|
|
| . |
|  |  |  |  |  |  | T | T |
|
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
| . |
|  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
275 | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | |
. | 300 | . | . | . | . | . | . | . | . |
  |