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Job DescriptionP0A8V2
Confidence100.00%DateWed Jan 25 15:20:19 GMT 2012
Rank4Aligned Residues908
% Identity31%Templatec2pmzB_
PDB info PDB header:translation, transferaseChain: B: PDB Molecule:dna-directed rna polymerase subunit b; PDBTitle: archaeal rna polymerase from sulfolobus solfataricus
Resolution3.40 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   15....20.........30.........40.........50.........60.........70.........80 ....
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Query Sequence  FGKRPQVLDVPYLLSIQLDSFQKFIEQDPEGQYGLEAAFRSVFPIQSYSGNSELQYVSYRLGEPVF. . . . . . . . . . DVQE
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Template Conservation    

   
    

  

 


 

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Template Sequence  WRVIEAYFKSKGLVRQHLDSYNDFVRN. . . . . . KLQEIIDEQGEIPTEIPGLKVRLGKIRIGKPRVRESDRGEREISPME
Template Known Secondary structure  TTS
TT
TTT......SSTTTT
S
SB



TTT












SSS





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   11........20.........30....... ..40.........50.........60.........70.........80....
 
   85....90.........100.........110.........120.........130... ......140
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Query Sequence  CQIRGVTYSAPLRVKLRLVIYEREAPEGTVKDIKEQEVYMGEIPLMTDN. . . . . . . . . . . . . . . . . . . . . . . . GTFVING
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Template Sequence  ARLRNLTYAAPLWLTMIPVENN. . . . . . . . IEAEPEEVYIGDLPIMLKSAIDPISQYTLDKLIEIGEDPKDPGGYFIVNG
Template Known Secondary structure  TTTT




B


BSSS........

S


B



B



TT
TTSGGGG

TS
TT






GGG
Template Predicted Secondary structure 





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   85....90.........100...... ...110.........120.........130.........140.........150......
 
   141........150.........160.........170.........180... ......190.........200.. .......210......
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Query Sequence  TERVIVSQLHRSPGVFFDSDKGKTHSSGKVLYNARIIPYRGSW. . . LDFEFDPKDNLFVRIDRRR. KLPATIILRALNYT
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Template Sequence  SERVIVTQEDLAPNRVLVDTGKT. . . GSNITHTAKIISSTAGYRVPVTIERLKDGTFHVSFPAVPGKIPFVILMRALGIL
Template Known Secondary structure  T





S


S...
SSS



SSS



TTTT
SSS
STT

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   157..160.........170......... 180.........190.........200.........210.........220.........230...
 
   217. .220.........230.........240.........250.........260.........270.........280.........290.....
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Query Sequence  TE. QILDLFFEKVIFEIRDNKLQMELVPERLRGETASFDIEANGKVYVEKGRRITARHIRQLEKDDVKLIEVPVEYIAGK
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Template Sequence  TDRDIVYAVSLD. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Template Known Secondary structure  S
SS....................................................................
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   234.....240.....
 
   296...300.........310.........320.........330.........340.........350.........360.........370.....
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Query Sequence  VVAKDYIDESTGELICAANMELSLDLLAKLSQSGHKRIETLFTNDLDHGPYISETLRVDPTNDRLSALVEIYRMMRPGEP
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Template Conservation  ............................................      
         
     

  
         
Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . PEVQNELFPSLEQASSIANVDDALDFIGSRVAIGQK
Template Known Secondary structure  ............................................
STTGGGSTGGGG




SSSTTTTTSSTTS
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   246...250.........260.........270.........280.
 
   376...380.........390.........400.........410.........420.........430.........440.........450...
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Query Sequence  . . PTREAAESLFENLFFSEDRYDLSAVGRMKFNRSLLREEIEGSGILSKDDIIDVMKKLIDIRNGKGEVDDIDHLGNRRI
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Template Sequence  RENRIEKAQQII. . . . . . . DKYFLPHLG. . . . . . . . . . . TSAEDRKKKAYYLAYAISKVIELYLGRREPDDKDHYANKRL
Template Known Secondary structure  GGGTT.......SSS

SS
...........
STTSSGGGTTTTT
SS



TT
TTS

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   282.......290... ......300.. .......310.........320.........330.........340...
 
   454.....460.........470......... 480.........490.........500.........510. ........520....
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Query Sequence  RSVGEMAENQFRVGLVRVERAVKERL. . SLGDLDTLMPQDMINAKPISAAVKEFFGSSQL. . . . . . . SQFMDQNNPLSEI
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Template Sequence  RLAGDLFASLFRVAFKAFVKDLTYQLEKSKVRGRKLALKALVRPDIVTERIRHALATGNWVGGRTGVSQLLDRTNWLSML
Template Known Secondary structure 

SSSS


GGGTS
TTTTTTTTSS


SSS

S



S
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   344.....350.........360.........370.........380.........390.........400.........410.........420...
 
   525....530.........540.........550.........560.........570.........580.
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Query Sequence  THKRRISALGPGGLTRERAGFEVRDVHPTHYGRVCPIETPEGPNIGLINSLSVYAQT. . . . . . . . . . . . . . . . . . . . . . .
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Template Sequence  SHLRRVIS. . . . SLARGQPNFEARDLHGTQWGRMCPFETPEGPNSGLVKNLALMAQIAVGINERIVEKTLYEMGVVPVEE
Template Known Secondary structure 
B

....SS


S


TTSS

SS
TTTB
SS


SSTTTTTSB
B
SS




STTTTTT
STT
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   424.....430. ........440.........450.........460.........470.........480.........490.........
 
   582.......590........
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . NEYGFLETPYRKVTDGV. . . . . .
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Template Sequence  VILKWSKVILNGRLIGYYQDGGELANKIRERRRKGEISDEVNVGHIVTDFINEVHVNCDSGRVRRPLIIVSNGNPLVTIE
Template Known Secondary structure 






SS
B

S

TTTTTTSS
TT



SS





B
SSS



T
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   500.........510.........520.........530.........540.........550.........560.........570.........
 
   599600.........610.........620.........630.........640.........650.........660..
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Query Sequence  . . . . . . . . . . . . . . . . VTDEIHYLSAIEEGNYVIAQANSNLDEEGHFVEDLVTCRSKGESSLFSRDQVDYMDVSTQQVVS
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Template Conservation                      

 
   
     

     
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Template Sequence  DIEKLESGAITFDDLVRQGKIEYLDAEEEENAYVALEPNDL. . . . . . . . . . . . . . . . . . . . . . . TPDHTHLEIWSPAILG
Template Known Secondary structure  TTS
SS
STTS
STTGGG

B
SSGGGG.......................
S

SB

S
TTTTS
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   593......600.........610.........620.........630... ......640.........
 
   663......670.........680.........690.........700.........710.........720.........730.........740..
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Query Sequence  VGASLIPFLEHDDANRALMGANMQRQAVPTLRADKPLVGTGMERAVAVDSGVTAVAKRGGVVQYVDASRIVIKVNEDEMY
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Template Sequence  ITASIIPYPEHNQSPRNTYQSAMAKQALGL. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . YAANY
Template Known Secondary structure  SGGGS
SS
TTB
GGGB
S
.............................................

TTT
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   650.........660.........670......... 680....
 
   743......750.........760.........770.........780.........790.........800.........810.........820..
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Query Sequence  PGEAGIDIYNLTKYTRSNQNTCINQMPCVSLGEPVERGDVLADGPSTDLGELALGQNMRVAFMPWNGYNFEDSILVSERV
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Template Sequence  QLRTDTRAHLLH. . . . . . . . . . YPQRPLVQTRALDIIG. . . . . . . . . . YTNRPAGNNAILAVMSFTGYNMEDSIIMNRSS
Template Known Secondary structure  TT


SS

S..........S



SSB
STTTTTS..........GGGS
S
BB
S

TT
STTT
B
BBS
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   685....690...... ...700.........710.. .......720.........730.........740....
 
   823......830.........840.........850....... ..860.........870.........880.........890.......
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Query Sequence  VQEDRFTTIHIQELACVSRDTKLGPEEITADIPNV. . . . . GEAALSKLDESGIVYIGAEVTGGDILVGKVTPKGETQLTP
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Template Sequence  VERGMYRSTFFRLYSTEEVKYPGGQEDKIVMPEAGVRGYKGKEYYRLLEDNGVVSPEVEVKGGDVLIGKVSP. . . . . . . .
Template Known Secondary structure  TTTT



S

SSSS




S


SSSSB
S
SS
GGGS
TTSB

SS

TT



B
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   745....750.........760.........770.........780.........790.........800.........810......
 
   898.900.........910.........920.........930.........940.........950.........960.........970.......
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Query Sequence  EEKLLRAIFGEKASDVKDSSLRVPNGVSGTVIDVQVFTRDGVEKDKRALEIEEMQLKQAKKDLSEELQILEAGLFSRIRA
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Template Conservation  ............    

 
      
 
 

 
 
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Template Sequence  . . . . . . . . . . . . PRAKRDTSIVTRHGEMGIVDLVLITETAEGN. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Template Known Secondary structure  ............



B




TT


TT

.....................................
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   817..820.........830.........840.......
 
   978.980.........990.........1000.........1010.........1020.........1030.........1040.........1050.......
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Query Sequence  VLVAGGVEAEKLDKLPRDRWLELGLTDEEKQNQLEQLAEQYDELKHEFEKKLEAKRRKITQGDDLAPGVLKIVKVYLAVK
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Template Conservation  ......................................................................  


 

  
Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . KLVKVRVRDL
Template Known Secondary structure  ......................................................................

Template Predicted Secondary structure  ......................................................................
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   860.........
 
   1058.1060.........1070.........1080.........1090.........1100.........1110.........1120.........1130.......
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Query Sequence  RRIQPGDKMAGRHGNKGVISKINPIEDMPYDENGTPVDIVLNPLGVPSRMNIGQILETHLGMAAKGIGDKINAMLKQQQE
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Template Sequence  RIPTIGDKFASRHGQKGVIGMLIPQVDMPYTVKGVVPDIILNPHALPSRMTLGQIMEGIAGKYAALSGNIVDATP. . . . .
Template Known Secondary structure 



TT
B
TTS


BB


B
TTTS
TTS


SB


GGGSGGG
BTTSSSS

B

T.....
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   870.........880.........890.........900.........910.........920.........930.........940....
 
   1138.1140.........1150.........1160.........1170.........1180.........1190.........1200.........1210.......
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Query Sequence  VAKLREFIQRAYDLGADVRQKVDLSTFSDEEVMRLAENLRKGMPIATPVFDGAKEAEIKELLKLGDLPTSGQIRLYDGRT
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Template Conservation  .................................................
           
 
 


  
 
 

 
 
Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . FYKTPIEQLQNEILRYGYLPDATEVVYDGRT
Template Known Secondary structure  .................................................T
SS
TTS
TT
B


TTT
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   945....950.........960.........970.....
 
   1218.1220.........1230.........1240.........1250.........1260.........1270.........1280.........1290.......
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Query Sequence  GEQFERPVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDD
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Template Sequence  GQKIKSRIYFGVVYYQKLHHMVADKLHARARGPVQILTRQPTEGRAREGGLRFGEMERDCLIGFGTAMLLKDRLLDNSDR
Template Known Secondary structure  T
SS

BB

BS

GGG




SS

B
TTT

B

BGGGTB




GGGTTTT
TTTTTTTTTTTT

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   976...980.........990.........1000.........1010.........1020.........1030.........1040.........1050.....
 
   1298.1300.... .....1310.........1320.........1330.........1340..
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Query Sequence  . . . . VNGRTKM. . . . . . . . . . . . YKNIVDGNHQMEPGMPESFNVLLKEIRSLGINIELEDE
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Template Sequence  TMIYVCDQCGYIGWYDKNKNKYVCPIHGDKSNLFPVTVSYAFKLLIQELMSMIISPRLVLE
Template Known Secondary structure 
TTT

S




GGG



SS
TTTT


TT







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   1056...1060.........1070.........1080.........1090.........1100.........1110......
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
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