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Job DescriptionP00452
Confidence100.00%DateThu Jan 5 10:56:38 GMT 2012
Rank2Aligned Residues669
% Identity30%Templatec3hnfA_
PDB info PDB header:oxidoreductaseChain: A: PDB Molecule:ribonucleoside-diphosphate reductase large subunit; PDBTitle: crystal structure of human ribonucleotide reductase 1 bound to the2 effectors ttp and datp
Resolution3.16 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   1920.........30..... ....40.........50.........60.........70.........80.........90......
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Query Sequence  LDKIHRVLDWAAEGLHN. . VSISQVELRSHIQFYDGIKTSDIHETIIKAAADLISRDAPDYQYLAARLAIFHLRKKAYGQ
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Template Sequence  FDKITSRIQKLCYGLNMDFVDPAQITMKVIQGLYSGVTTVELDTLAAETAATLTT. KHPDYAILAARIAVSNLHKETKKV
Template Known Secondary structure  GGGGTTS
TTT

TTS

SS

GGG.T
TTTS
S
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   15....20.........30.........40.........50.........60......... 70.........80.........90...
 
   97..100.........110......... 120.........130.........140.........150.........160.........170...
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Query Sequence  FEPPALYDHVVKMVEMGKYDNHL. . . LEDYTEEEFKQMDTFIDHDRDMTFSYAAVKQLEGKYLVQNRVTGEIYESAQFLY
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Template Sequence  FSDVMEDLYNYINPHNGKHSPMVAKSTLDIVLANKDRLNSAIIYDRDFSYNYFGFKTLERSYLLKI. . NGKVAERPQHML
Template Known Secondary structure 
B
TTT

B

SS
TTTT

GGGGGSS
TS
BS..SSSB


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   94.....100.........110.........120.........130.........140.........150......... 160.........170.
 
   174.....180.........190.........200.........210.........220.........230 .........240.........250..
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Query Sequence  ILVAACLFSNYPRETRLQYVKRFYDAVSTFKISLPTPIMSGVRTPTRQFSSCVLIEC. GDSLDSINATSSAIVKYVSQRA
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Template Sequence  MRVSVGIHK. . . . . EDIDAAIETYNLLSERWFTHASPTLFNAGTNRPQLSSCFLLSMKDDSIEGIYDTLKQCALISKSAG
Template Known Secondary structure  T.....T
TTS
TTSSS








SST

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   172.......180 .........190.........200.........210.........220.........230.........240......
 
   253......260.........270.........280.........290.........300.........310.........320.........330..
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Query Sequence  GIGINAGRIRALGSPIRGGEAFHTGCIPFYKHFQTAVKSCSQGGVRGGAATLFYPMWHLEVESLLVLKNNRGVEGNRVRH
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Template Sequence  GIGVAVSCIRATGSYIAGTNGNSNGLVPMLRVYNNTARYVDQP. . . . GAFAIYLEPWHLDIFEFLDLKK. . . . . . . . . RD
Template Known Secondary structure 

TTS

TT
TTTT






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TTBTTTTS

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   247..250.........260.........270.........280......... 290.........300.........310. ..
 
   333......340.........350.........360.........370.........380.........390.........400.........410..
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Query Sequence  MDYGVQINKLMYTRLLKGEDITLFSPSDVPGLYDAFFADQEEFERLYTKYEKDDSIRKQRVKAVELFSLMMQERASTGRI
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Template Sequence  LFFALWIPDLFMKRVETNQDWSLMCPNECPGLDEVW. . . GEEFEKLYASYEKQGRVRKV. VKAQQLWYAIIESQTETGTP
Template Known Secondary structure 
TT
B
TTTSTTTTS

...TT


S.S
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   328.330.........340.........350.........360... ......370.........380... ......390.........400...
 
   413......420.........430.........440.........450.........460.........470.. .......480......
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Query Sequence  YIQNVDHCNTHSPFDPAIAPVRQSNLCLEIALPTKPLNDVNDENGEIALCTLSAFNLGAI. . . . . . NNLDELEELAILAV
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Template Sequence  YMLYKDSCNRKSN. QQNLGTIKCSNLCTEIVEYTSK. . . . . . . . DEVAVCNLASLALNMYVTSEHTYDFKKLAEVTKVVV
Template Known Secondary structure  T
T.TGGG






TTS






S........S


B

GGGSB
TTS
B
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   404.....410...... ...420.........430........ .440.........450.........460.........470....
 
   487..490.........500.........510.........520.........530.........540.........550.........560......
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Query Sequence  RALDALLDYQDYPIPAAKRGAMGRRTLGIGVINFAYYLAKHGKRYSDGSANNLTHKTFEAIQYYLLKASNELAKEQGACP
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Template Sequence  RNLNKIIDINYYPVPEACLSNKRHRPIGIGVQGLADAFILMRYPFESAEAQLLNKQIFETIYYGALEASCDLAKEQGPYE
Template Known Secondary structure 


SS



T

TTS


T
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   475....480.........490.........500.........510.........520.........530.........540.........550....
 
   567..570.........580.........590.........600.........610.........620.........630.........640......
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Query Sequence  WFNETTYAKGILPIDTYKKDLDTIANEPLHYDWEALRESIKTHGLRNSTLSALMPSETSSQISNATNGIEPPRGYVSIKA
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Template Sequence  TYEGSPVSKGILQYDMWNVTPTDL. . . . . . WDWKVLKEKIAKYGIRNSLLIAPMPTASTAQILGNNESIEPYTSNIYTRR
Template Known Secondary structure  T
TTSTTTTT

TT



TT......S


S
S

B




TT


TT


S
S

B
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   555....560.........570........ .580.........590.........600.........610.........620........
 
   647..650......... 660.........670.........680.........690....
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Query Sequence  SKDGILRQVVPDY. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . EHLHDAYELLWEMPGNDGYLQLVGIMQKFIDQSIS
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Template Sequence  VLSGEFQIVNPHLLKDLTERGLWHEEMKNQIIACNGSIQSIPEIPDDLKQLYKTVWEI. SQKTVLKMAAERGAFIDQSQS
Template Known Secondary structure 
SSSB


TT


TTT

TT
TTS
T

GGGS.
TTS
SS


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   629630.........640.........650.........660.........670.........680...... ...690.........700.......
 
   695....700.........710.........720........ .730.....
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Query Sequence  ANTNYDPSRFPSGKVPMQQLLKDLLTAYKFGVKT. LYYQNTR
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Template Sequence  LNIHI. . . . . . AEP. NYGKLTSMHFYGWKQGLKTGMYYLRTR
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   708.710.. ... ....720.........730.........740..
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
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