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Job DescriptionP00452
Confidence100.00%DateThu Jan 5 10:56:38 GMT 2012
Rank3Aligned Residues622
% Identity30%Templatec2wghA_
PDB info PDB header:oxidoreductaseChain: A: PDB Molecule:ribonucleoside-diphosphate reductase large PDBTitle: human ribonucleotide reductase r1 subunit (rrm1) in complex2 with datp and mg.
Resolution2.30 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   80.........90.........100.........110......... 120.........130.........140.........150......
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Query Sequence  LAARLAIFHLRKKAYGQFEPPALYDHVVKMVEMGKYDNHL. . . LEDYTEEEFKQMDTFIDHDRDMTFSYAAVKQLEGKYL
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Template Sequence  LAARIAVSNLHKETKKVFSDVMEDLYNYINPHNGKHSPMVAKSTLDIVLANKDRLNSAIIYDRDFSYNYFGFKTLERSYL
Template Known Secondary structure 
TS
S

B
TTT

B

SS
TT

GGGGGGS
TS
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   77..80.........90.........100.........110.........120.........130.........140.........150......
 
   157..160.........170.........180.........190.........200.........210.........220.........230 .....
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Query Sequence  VQNRVTGEIYESAQFLYILVAACLFSNYPRETRLQYVKRFYDAVSTFKISLPTPIMSGVRTPTRQFSSCVLIEC. GDSLD
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Template Sequence  LKI. . NGKVAERPQHMLMRVSVGIHK. . . . . EDIDAAIETYNLLSERWFTHASPTLFNAGTNRPQLSSCFLLSMKDDSIE
Template Known Secondary structure 
..TT


T.....T
TS
TTSSS







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   157.. 160.........170.........180 .........190.........200.........210.........220.........
 
   236...240.........250.........260.........270.........280.........290...... ...300.........310....
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Query Sequence  SINATSSAIVKYVSQRAGIGINAGRIRALGSPIRGGEAFHTGCIPFYKHFQTAVKSCSQGG. VRGGAATLFYPMWHLEVE
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Template Sequence  GIYDTLKQCALISKSAGGIGVAVSCIRATGSYIAGTNGNSNGLVPMLRVYNNTARYVDQGGNKRPGAFAIYLEPWHLDIF
Template Known Secondary structure  TT

TTS

TT
GGGT


S
STTSS




TTBTT
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   230.........240.........250.........260.........270.........280.........290.........300.........
 
   315....320.........330.........340.........350.........360.........370.........380.........390....
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Query Sequence  SLLVLKNNRGVEGNRVRHMDYGVQINKLMYTRLLKGEDITLFSPSDVPGLYDAFFADQEEFERLYTKYEKDDSIRKQRVK
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Template Sequence  EFLDLKKNTGKEEQRARDLFFALWIPDLFMKRVETNQDWSLMCPNECPGLDEVW. . . GEEFEKLYASYEKQGRVRKV. VK
Template Known Secondary structure  TTTT
SSS
GGG

TTS
TT
B
TTTSTTGGG

...TTT

S.
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   310.........320.........330.........340.........350.........360... ......370.........380... ..
 
   395....400.........410.........420.........430.........440.........450.........460.........470..
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Query Sequence  AVELFSLMMQERASTGRIYIQNVDHCNTHSPFDPAIAPVRQSNLCLEIALPTKPLNDVNDENGEIALCTLSAFNLGAI. .
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Template Sequence  AQQLWYAIIESQTETGTPYMLYKDSCNRKSN. QQNLGTIKCSNLCTEIVEYTSK. . . . . . . . DEVAVCNLASLALNMYVT
Template Known Secondary structure  S

T
T.TGGG






TTS





BT........TB

GGGGB
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   386...390.........400.........410...... ...420.........430........ .440.........450......
 
   473......480.........490.........500.........510.........520.........530.........540........
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Query Sequence  . . . . NNLDELEELAILAVRALDALLDYQDYPIPAAKRGAMGRRTLGIGVINFAYYLAKHGKRYSDGSANNLTHKTFEAIQ
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Template Sequence  SEHTYDFKKLAEVTKVVVRNLNKIIDINYYPVPEACLSNKRHRPIGIGVQGLADAFILMRYPFESAEAQLLNKQIFETIY
Template Known Secondary structure  TTS
B



SS



TT

TTS
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   457..460.........470.........480.........490.........500.........510.........520.........530......
 
   549550.........560.........570.........580.........590.........600.........610.........620........
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Query Sequence  YYLLKASNELAKEQGACPWFNETTYAKGILPIDTYKKDLDTIANEPLHYDWEALRESIKTHGLRNSTLSALMPSETSSQI
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Template Sequence  YGALEASCDLAKEQGPYETYEGSPVSKGILQYDMWNVTPTDL. . . . . . WDWKVLKEKIAKYGIRNSLLIAPMPTASTAQI
Template Known Secondary structure 


TT
TTSSGGGT

TT



SS......S


S
S

B




TT
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   537..540.........550.........560.........570........ .580.........590.........600.........610
 
   629630.........640......... 650.........660.........670.........680.........690........
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Query Sequence  SNATNGIEPPRGYVSIKASKD. . . . . . . . . . GILRQVVPDYEHLHDAYELLWEMPGNDGYLQLVGIMQKFIDQSISANTN
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Template Sequence  LGNNESIEPYTSNIYQIVNPHLLKDLTERGLGSIQSIPEIPDDLKQLYKTVWEI. SQKTVLKMAAERGAFIDQSQSLNIH
Template Known Secondary structure  T


TT




SB


B
T



TT
SSS
T

TTSS.
TT
SS




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   611........620.........630.........640.........650.........660.... .....670.........680.........
 
   699700.........710.........720........ .730.....
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Query Sequence  YDPSRFPSGKVPMQQLLKDLLTAYKFGVKT. LYYQNTR
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Template Sequence  I. . . . . . A. EPNYGKLTSMHFYGWKQGLKTGMYYLRTR
Template Known Secondary structure 
......S.S

TT
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   712 . ......720.........730.........740..
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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