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Job DescriptionP00452
Confidence100.00%DateThu Jan 5 10:56:38 GMT 2012
Rank7Aligned Residues546
% Identity20%Templatec1xjeA_
PDB info PDB header:oxidoreductaseChain: A: PDB Molecule:ribonucleotide reductase, b12-dependent; PDBTitle: structural mechanism of allosteric substrate specificity in a2 ribonucleotide reductase: dttp-gdp complex
Resolution1.90 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   130.........140.........150.........160.........170.........180.... .....190.........
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Query Sequence  QMDTFIDHDRDMTFSYAAVKQLEGKYLVQNRVTGEIYESAQFLYILVAACLFSNY. . . . . . . . . . PRETRLQYVKRFYDA
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Template Sequence  KLSDLISRWIDVEPSKNAQIILRDRYFMKDLDGNYLETKWEDVARRVARVVATAELLNPSYKKNEKLDRIKEWEDIFFRV
Template Known Secondary structure 
T



TS
B
TT

BS

SGGGGG
TT

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   2.......10.........20.........30.........40.........50.........60.........70.........80.
 
   200.........210...... ...220.........230.........240.........250..
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Query Sequence  VSTFKISLPTPIMSGVR. . . . . . . . . . . . . . . . . . . . . . . . . . . TPTRQFSSCVLIECGDSLDSINATSSAIVKYVSQRA
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Template Sequence  LKARLFIPNSPTLFNAGLGVKHDLLWKPIDQMTLEDYEEIYRSRNHLHMLSACFVVPVGDSIEEIFEAVKEYALITKVGG
Template Known Secondary structure  TTS
TTTTS
SS
GGG



TT








SSTT
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   82.......90.........100.........110.........120.........130.........140.........150.........160.
 
   253......260.........270.........280.........290.........300.........310.........320.........330..
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Query Sequence  GIGINAGRIRALGSPIRGGEAFHTGCIPFYKHFQTAVKSCSQGGVRGGAATLFYPMWHLEVESLLVLKNNRGVEGNRVRH
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Template Sequence  GVGSNFSELRPKGSFVAGTHGKASGPVSFMHVFNSAISVVKQGSRRRGALMGILNINHPDIEEFIDAKK. . . . . . . VLNF
Template Known Secondary structure 
TTS

TT
TTTT


TT
TTT

TTSTTTS

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TT
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   162.......170.........180.........190.........200.........210.........220.........230 ....
 
   333...... 340.........350.........360.........370.........380.........390.........400.........
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Query Sequence  MDYGVQI. . . NKLMYTRLLKGEDITLFSPSDVPGLYDAFFADQEEFERLYTKYEKDDSIRKQRVKAVELFSLMMQERAST
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Template Sequence  FNLSVGFPMDKKEILKLYEEDGELELSHPRST. . . . . . . . . . . . . . . . . . . . . . . . . . . IRKKVKIRELFRKIATNAWKS
Template Known Secondary structure 

S
TT


TT
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   241........250.........260.........270.. .......280.........290...
 
   410.........420.........430.........440.........450.........460.........470.. .......480....
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Query Sequence  GRIYIQNVDHCNTHSPFDPAIAPVRQSNLCLEIALPTKPLNDVNDENGEIALCTLSAFNLGAI. . . . . NNLDELEELAIL
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Template Sequence  GDPGLAFLGEMNKYYPL. YPHRKINSTNPCGEIGLSDY. . . . . . . . . . . . EACNLGSIDVAKFYNNGFVDLEALQELVQI
Template Known Secondary structure  S


T
TT.TTTS

TTS

TT............
GGGGTT
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   294.....300.........310 .........320.........330 .........340.........350.........360
 
   485....490.........500.........510.........520.........530.........540.........550.........560....
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Query Sequence  AVRALDALLDYQDYPIPAAKRGAMGRRTLGIGVINFAYYLAKHGKRYSDGSANNLTHKTFEAIQYYLLKASNELAKEQGA
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Template Sequence  AVRFLDNVIDVNVFPIDKITKAVKESRRLGLGIMGFADLLYKLEIPYNSQEARDFAANLMAFIALHAHRTSYELGKEKGN
Template Known Secondary structure 


SS


T

SSS

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   361........370.........380.........390.........400.........410.........420.........430.........440
 
   565....570.........580.........590.........600.........610.........620.........630.........640....
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Query Sequence  CPWFNETTYAKGILPIDTYKKDLDTIANEPLHYDWEALRESIKTHGLRNSTLSALMPSETSSQISNATNGIEPPRGYVSI
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Template Sequence  FPLLEISRYRTE. DNFVPFAMGMSNYDD. . . . . . EIREVMKMTKEFRRNVALLTIAPTGSISNIADTSSGLEPNFLLAYT
Template Known Secondary structure 
TTGGGSS.SS

SS


S
TT......TTT

S
S

B
B


TTTTS

TT


S
S
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   441........450.. .......460....... ..470.........480.........490.........500.........510...
 
   645....650......... 660.........670.........680.........690
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Query Sequence  KASKDGILRQVVPDY. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . EHLHDAYELLWEMPGNDGYLQLVGIMQKFID
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Template Sequence  RFVTKEDGTKEPLLYVNQVLREKLNPEILKRIEKELIEKGSLKDIPDVPEKIKKVFVVALDI. DPMDHLLMQDAFQRYVD
Template Known Secondary structure 

SSS



S
SSSTT
TTS
S

GGGS.
TT
S
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   514.....520.........530.........540.........550.........560.........570..... ....580.........590..
 
   691........700.........710.........720.........730......
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Query Sequence  QSISANTNYDPSRFPSGKVPMQQLLKDLLTAYKFGVKTLYYQNTRD
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Template Sequence  NNISKTINM. . . . . . PQSATVDDVLNVYLEALRTNVRGITVYRDGS
Template Known Secondary structure  S
B


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TT

SS
S
TT
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   593......600. ........610.........620.........630..
 
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Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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