Job Description P77455 Confidence 100.00% Date Thu Jan 5 12:29:26 GMT 2012 Rank 14 Aligned Residues 468 % Identity 18% Template c1t90B_ PDB info PDB header:oxidoreductase Chain: B: PDB Molecule:probable methylmalonate-semialdehyde PDBTitle: crystal structure of methylmalonate semialdehyde2 dehydrogenase from bacillus subtilis Resolution 2.50 Å

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		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.		.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.
Predicted Secondary structure																	.
Query SS confidence																	.
Query Sequence		M	Q	Q	L	A	S	F	L	S	G	T	W	Q	S	G	.	R	G	R	S	R	L	I	H	H	A	I	S	G	E	A	L	W	E	V	T	S	E	G	L	D	M	A	A	A	R	Q	F	A	I	E	K	G	A	P	A	L	R	A	M	T	F	I	E	R	A	A	M	L	K	A	V	A	K	H	L	L	S	E	K
Query Conservation																	.
Alig confidence																	.
Template Conservation
Template Sequence		I	R	K	L	K	N	Y	I	N	G	E	W	V	E	S	K	T	D	Q	Y	E	D	V	V	N	P	A	T	K	E	V	L	C	Q	V	P	I	S	T	K	E	D	I	D	Y	A	A	Q	T	A	A	E	A	F	K	T	W	S	K	V	A	V	P	R	R	A	R	I	L	F	N	F	Q	Q	L	L	S	Q	H	K
Template Known Secondary structure				B						T	T						S		S								T	T	T	T																													T	T	S																			T
Template Predicted Secondary structure
Template SS confidence
		4	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.
		80	.	.	.	.		.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.
Predicted Secondary structure							.
Query SS confidence							.
Query Sequence		E	R	F	Y	A	.	L	S	A	Q	T	G	A	T	R	A	D	S	W	V	D	I	E	G	G	I	G	T	L	F	T	Y	A	S	L	G	S	R	E	L	P	D	D	T	L	W	P	E	D	E	L	I	P	L	S	K	E	G	G	F	A	A	R	H	L	L	T	S	K	S	G	V	A	V	H	I	N	A	F	N
Query Conservation							.
Alig confidence							.																																															.	.	.	.	.	.	.	.	.	.
Template Conservation																																																						.	.	.	.	.	.	.	.	.	.
Template Sequence		E	E	L	A	H	L	I	T	I	E	N	G	K	N	T	K	E	A	L	G	E	V	G	R	G	I	E	N	V	E	F	A	A	G	A	P	S	L	M	M	G	D	S	L	A	S	I	A	T	D	V	E	.	.	.	.	.	.	.	.	.	.	A	A	N	Y	R	Y	P	I	G	V	V	G	G	I	A	P	F	N
Template Known Secondary structure																																		T	T															T	T			.	.	.	.	.	.	.	.	.	.									S								S	S
Template Predicted Secondary structure																																																						.	.	.	.	.	.	.	.	.	.
Template SS confidence
		84	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.											.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.
		159	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.			.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.
Predicted Secondary structure																																																									.	.
Query SS confidence																																																									.	.
Query Sequence		F	P	C	W	G	M	L	E	K	L	A	P	T	W	L	G	G	M	P	A	I	I	K	P	A	T	A	T	A	Q	L	T	Q	A	M	V	K	S	I	V	D	S	G	L	V	P	E	G	A	I	S	L	I	C	G	.	.	S	A	G	D	L	L	D	H	L	D	S	Q	D	V	V	T	F	T	G	S	A	A	T
Query Conservation																																																									.	.
Alig confidence																																													.												.	.
Template Conservation																																													.
Template Sequence		F	P	M	M	V	P	C	W	M	F	P	M	A	I	A	L	G	N	T	F	I	L	K	P	S	E	R	T	P	L	L	T	E	K	L	V	E	L	F	E	K	A	G	.	L	P	K	G	V	F	N	V	V	Y	G	A	H	D	V	V	N	G	I	L	E	H	P	E	I	K	A	I	S	F	V	G	S	K	P	V
Template Known Secondary structure			T	T													T	T									T	T	S														T	T	.			T	T	S							S											T	T								S
Template Predicted Secondary structure																																													.
Template SS confidence
		154	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.		.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.
		237	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		G	Q	M	L	R	V	Q	P	N	I	V	A	K	S	I	P	F	T	M	E	A	D	S	L	N	C	C	V	L	G	E	D	V	T	P	D	Q	P	E	F	A	L	F	I	R	E	V	V	R	E	M	T	T	K	A	G	Q	K	C	T	A	I	R	R	I	I	V	P	Q	A	L	V	N	A	V	S	D	A	L	V
Query Conservation
Alig confidence								.	.																										.	.	.	.	.
Template Conservation								.	.																										.	.	.	.	.
Template Sequence		G	E	Y	V	Y	K	.	.	K	G	S	E	N	L	K	R	V	Q	S	L	T	G	A	K	N	H	T	I	V	L	N	D	A	.	.	.	.	.	N	L	E	D	T	V	T	N	I	V	G	A	A	F	G	S	A	G	E	R	C	M	A	C	A	V	V	T	V	E	E	G	I	A	D	E	F	M	A	K	L	Q
Template Known Secondary structure								.	.					T	T																	T	T		.	.	.	.	.															G	G	G	G			T	T									T	T	T
Template Predicted Secondary structure								.	.																										.	.	.	.	.
Template SS confidence
		233	.	.	.	.	.			.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.						.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.
		317	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		A	R	L	Q	K	V	V	V	G	D	P	A	Q	E	G	V	K	M	G	A	L	V	N	A	E	Q	R	A	D	V	Q	E	K	V	N	I	L	L	A	A	G	C	E	I	R	L	G	G	Q	A	D	L	S	A	A	G	A	F	F	P	P	T	L	L	Y	C	P	Q	P	D	E	T	P	A	V	H	A	T	E	A
Query Conservation
Alig confidence																																																																										.	.
Template Conservation																																																																										.	.
Template Sequence		E	K	V	A	D	I	K	I	G	N	G	L	D	D	G	V	F	L	G	P	V	I	R	E	D	N	K	K	R	T	L	S	Y	I	E	K	G	L	E	E	G	A	R	L	V	C	D	G	R	E	N	V	S	D	D	G	Y	F	V	G	P	T	I	F	D	N	V	T	T	E	M	T	.	.	I	W	K	D	E	I
Template Known Secondary structure						T			B	S		T	T	S	T	T			B				S	S																		T							T	T	S	S			S	S	S	S									S			T	T	S		.	.				S
Template Predicted Secondary structure																																																																										.	.
Template SS confidence
		306	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.			.	.	380	.	.	.
		397	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		F	G	P	V	A	T	L	M	P	A	Q	N	Q	R	H	A	L	Q	L	A	C	A	G	G	G	S	L	A	G	T	L	V	T	A	D	P	Q	I	A	R	Q	F	I	A	D	A	A	R	T	H	G	R	I	Q	I	L	N	E	E	S	A	K	E	S	T	G	H	G	S	P	L	P	Q	L	V	H	G	G	P	G
Query Conservation
Alig confidence																																																		.	.														.	.	.	.	.	.	.	.
Template Conservation																																																		.	.														.	.	.	.	.	.	.	.
Template Sequence		F	A	P	V	L	S	V	I	R	V	K	N	L	K	E	A	I	E	I	A	N	K	S	E	F	A	N	G	A	C	L	F	T	S	N	S	N	A	I	R	Y	F	R	E	N	I	D	A	.	.	G	M	L	G	I	N	L	G	V	P	A	P	M	.	.	.	.	.	.	.	.	A	F	F	P	F	S	G	W	K
Template Known Secondary structure			S	S								S	S											S	S			S																						.	.	S					S		S						.	.	.	.	.	.	.	.	T	T	S		B
Template Predicted Secondary structure																																																		.	.														.	.	.	.	.	.	.	.
Template SS confidence
		384	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.			.	.	.	.	.	.	.	.	440	.	.	.	.									.	.	.	.	.	450	.	.	.
		477	.	.	480	.			.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.
Predicted Secondary structure							.	.
Query SS confidence							.	.
Query Sequence		R	A	G	G	G	.	.	E	E	L	G	G	L	R	A	V	K	H	Y	M	Q	R	T	A	V
Query Conservation							.	.
Alig confidence							.	.			.
Template Conservation											.
Template Sequence		S	S	F	F	G	T	L	H	A	.	N	G	K	D	S	V	D	F	Y	T	R	K	K	V	V
Template Known Secondary structure		T	T			S	S	S		B	.	S								T
Template Predicted Secondary structure											.
Template SS confidence
		454	.	.	.	.	.	460	.	.		.	.	.	.	.	.	.	470	.	.	.	.	.	.	.