|   |
4 | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | |
. | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | |
|
. | . | . | . | . | . | . | 40 | . | . | . | . | |
. | . | . | . | . | 50 | . | . | . | . | . | |
|
. | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |  |
|
|  |  |  |  |  |  | . |  |  |  |  |  |  |  |  |  |  |  |
|
|
| . | . |
|
|
|  |  |  |  |  |
|  |  |  | . |  |  |  |  |  |  |  |
|
|
|  | . | . |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
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|
|
|
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|
|
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|
|
|
|
|
|
|
|
|
Query Sequence |   |
I | K | I | G | L | A | L | G | S | G | A | A | R | G | W | . |
S | H | I | G | V | I | N | A | L | K | K | V | G | I | . |
. |
E | I | D | I | V | A | G | C | S | I | G | S | . |
L | V | G | A | A | Y | A | C | D | R | L | . |
. |
S | A | L | E | D | W | V | T | S | F | S | Y | W | D | V | L | R | L | M | D | L | S |
Query Conservation |   |
  |
|
|
|
|   |
|   |
|
|
|   |
|
|   | . |   |   |   |
|
|
|   |   |
|   |
|   |
|
| . | . |   |   |
|   |
|   |
|
|
|   |
|
| . |
|   |
|
|   |   |
|   |
|   |   | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
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|
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|
|
| . | . |
|
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|
|
| . |
|
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|
|
| . | . |
|
|
|
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|
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|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
Template Conservation |   |
|   |
|
|
|
|   |
|
|
|
|   |
|
|
|   |   |
|   |
|   |
|   |
|
|   |   |   |
|
|
|
|   |
|
|
|
|
|
|
|
|
|
|
|
|   |   |   |
|
|
|   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   | . | . | . | . | . | . |
Template Sequence |   |
P | V | V | A | I | L | G | S | G | G | G | F | R | A | M | V | G | F | S | G | V | M | K | A | L | Y | E | S | G | I | L | D | C | A | T | Y | V | A | G | L | S | G | S | T | W | Y | M | S | T | L | Y | S | H | P | D | F | P | E | K | G | P | E | E | I | N | E | E | L | M | K | N | V | S | H | . |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | S |
| G | G | G |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |
| T | T | T | T | T | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  | S | . | . | . | . | . | . |
Template Predicted Secondary structure |   |
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
| . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
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|
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|
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|
  |   |
188 | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | |
|
|
|
|
|
  |
  |   |
78 | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | |
|
|
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|
|
. | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | |
. | . | . | . | . | . | . | . | 120 | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|  |  |  |  |  |  |
|
|
|
|  |  |  | . |  |  |  |  |
|
|
|
|
|  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
W | Q | R | G | G | L | L | R | G | E | R | V | F | N | Q | Y | R | E | I | M | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
P | E | T | E | I | E | N | C | S | R | R | F | A | A | . |
V | A | T | N | L | S | T | G | R | E | L |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |
|   |
| . |   |
|
|   |   |   |
|   |   |   |   |
Alig confidence |   |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|
|
|
|   |
|
|   |   |
|   |   |   |
|   |   |   |   |   |   |   |
|
|
|   |   |   |   |   |   |   |   |
|   |   |
|   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |
Template Sequence |   |
. |
N | P | L | L | L | L | T | P | Q | K | V | K | R | Y | V | E | S | L | W | K | K | K | S | S | G | Q | P | V | T | F | T | D | I | F | G | M | L | I | G | E | T | L | I | H | N | R | M | N | T | T | L | S | S | L | K | E | K | V | N | T | A | Q | C | P | L | P | L | F | T | C | L | H | V | K | P | D | V | S | E |
Template Known Secondary structure |   |
. |
| G | G | G | G |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | G | G | G | T | T |
| B | S | G | G | G | G | G | G | T | T | T | S |
| S |
|  |  |  |  |  |  |  |  |
|
| S | S |
|
|
|
Template Predicted Secondary structure |   |
. |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
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|
|
|
|
|
  |   |
|
262 | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 |
  |
  |   |
|
|
|
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|
|
123 | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Query SS confidence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
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|
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|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
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. |
. |
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. |
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. |
W | F | T | E | G | D | L | H | L | A | I | R | A | S | C | S | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |
|   |   |   |   |
|   |   |
|
|   |
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
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|
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|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
  |   |   |   |   |   |
|
|
|
|
|   |
|   |
|   |   |
|   |
|
|
|
|   |   |   |   |
|
|
|   |
|   |   |
|   |   |
|   |   |   |
|
|   |   |
|   |
|
|   |
|
|
|
|
|   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
L | M | F | A | D | W | V | E | F | S | P | Y | E | I | G | M | A | K | Y | G | T | F | M | A | P | D | L | F | G | S | K | F | F | M | G | T | V | V | K | K | Y | E | E | N | P | L | H | F | L | M | G | V | W | G | S | A | F | S | I | L | F | N | R | V | L | S | T | M | E | E | E | L | E | N | I | T | T | K | H | I |
Template Known Secondary structure |   |
G | G | G | S |  |  |  |  |  |
| S | S |
|  |  |  | T | T | T | T |  |  |  |
| G | G | G | T | T | S |  |  |  | T | T |  |  |  |  |
|
|
|
|
| B |  |  |  |  |  |  |  |  | T | T |  |  |  |  | T |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
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|
|  |  |
|
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|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
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|
  |   |
341 | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 |
  |
  |   |
|
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|
139 | 140 | . | . | . | . | . | . | . | . | |
|
|
|
. | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | |
|
. | 170 | . | . | . | . | . | . | . | . | . | 180 |
Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
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|
|
|  |  |  | . | . | . | . |
|
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  | . | . |  |
|
|
|
|  |  |  |  |  |  |
|
Query SS confidence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
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. |
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|
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| . |
. |
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. |
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|
| . |
. |
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|
Query Sequence |   |
. |
. |
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N | G | Y | W | L | V | D | G | A | V | V | N | P | I | P | I | S | L | T | R | . |
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A | L | G | A | D | I | V | I | A | V | D | L |
Query Conservation |   |
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Alig confidence |   |
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Template Conservation |   |
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Template Sequence |   |
V | S | N | N | Q | A | S | W | I | H | R | M | I | M | A | L | V | S | D | S | A | L | F | N | T | R | E | G | R | A | G | K | V | H | N | F | M | L | G | L | N | L | D | V | K | S | K | K | I | H | V | V | D | S | G | L | T | F | N | L | P | Y | P | L | I | L | R | P | Q | R | G | V | D | L | I | I | S | F | D | F |
Template Known Secondary structure |   |
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Template Predicted Secondary structure |   |
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Template SS confidence |   |
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  |   |
430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . |
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181 | . | . | . | . | . | . | . | . | 190 | . |
Predicted Secondary structure |   |
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Query SS confidence |   |
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Query Sequence |   |
Q | H | D | A | H | L | M | Q | Q | D | L |
Query Conservation |   |
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Alig confidence |   |
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Template Conservation |   |
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Template Sequence |   |
S | A | R | P | S | D | S | S | P | P | F |
Template Known Secondary structure |   |
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| S | S | T | T | S |
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Template Predicted Secondary structure |   |
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Template SS confidence |   |
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577 | . | . | 580 | . | . | . | . | . | . | . |
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