|   |
310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | |
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 |
Predicted Secondary structure |   |
 |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| . | . | . | . | . | . | . | . | . |
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
S | V | G | I | L | G | G | G | L | M | G | G | G | I | A | Y | V | T | A | C | K | A | . |
. |
. |
. |
. |
. |
. |
. |
. |
G | I | P | V | R | I | K | D | I | N | P | Q | G | I | N | H | A | L | K | Y | S | W | D | Q | L | E | G | K | V | R | R | R | H | L | K | A | S | E | R | D | K | Q | L | A | L | I | S | G | T |
Query Conservation |   |
  |
|   |
|
|
|
|
|   |
|
|   |
|
|
|   |   |   |
|   |   |
| . | . | . | . | . | . | . | . | . |
|   |   |
|   |
|   |
|   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|
|
|
|
|   |
|   |
|
|   |
|
|   |   |   |
|   |   |   |   |   |   |
|   |   |
|   |
|   |   |
|   |
|   |   |
|   |   |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|   |   |
|   |
|   |   |   |   |   |   |   |
|   |
Template Sequence |   |
H | V | G | L | L | G | L | G | T | V | G | G | G | T | L | T | V | L | R | R | N | A | E | E | I | T | R | R | A | G | R | E | I | R | V | V | R | A | A | V | R | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
N | L | D | K | A | E | A | L | A | G | G | L | P | L | T |
Template Known Secondary structure |   |
 |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | T |  |  |  |  |  |  |  |  | S | S |
|  |  |  |  |  |  |  |
| S | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|  |  |  |  |  |  |  |  | T | T |
|
|  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
5 | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 |
  |
  |   |
381 | . | . | . | . | . | |
|
|
. | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|  |  |  |  | . | . | . |
|
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |
Query SS confidence |   |
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
T | D | Y | R | G | F | . |
. |
. |
A | H | R | D | L | I | I | E | A | V | F | E | N | L | E | L | K | Q | Q | M | V | A | E | V | E | Q | N | C | A | A | H | T | I | F | A | S | N | T | S | S | L | P | I | G | D | I | A | A | H | A | T | R | P | E | Q | V | I | G | L | H | F | F | S | P | V | E | K | M | P | L | V |
Query Conservation |   |
  |
|   |   |   |
| . | . | . |   |   |
|
|
|
|
|
|
|
|   |
|   |
|   |   |
|   |   |
|   |   |   |
|   |   |   |   |   |   |   |
|
|
|
|
|
|
|
|   |
|   |
|   |   |
|
|   |   |   |   |   |
|   |
|   |   |
|   |
|
|
|
|
|   |   |   |
|   |
|
|
Alig confidence |   |
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |   |
|
|
|   |
|   |   |
|
|
|
|
|
|   |
|
|   |   |   |   |
|   |   |   |
|   |   |
|
|   |
|
|
| . | . | . |
|
|
|
|
|
|
| . | . |
|
|
|
|   |   |
|   |
|
|   |   |
|
|   |   |   |
|
|   |
|   |   |
|
|
|
|   |
|
|
|
Template Sequence |   |
T | N | P | F | D | V | V | D | D | P | E | I | D | I | V | V | E | L | I | G | G | L | E | P | A | R | E | L | V | X | Q | A | I | A | N | G | K | . |
. |
. |
H | V | V | T | A | N | K | . |
. |
H | L | V | A | K | Y | G | N | E | I | F | A | A | A | Q | A | K | G | V | X | V | T | F | E | A | A | V | A | G | G | I |
Template Known Secondary structure |   |
S |
| T |  |  |  |  | T |
| T | T |
|
|  |  |  |  |
|
|
| S | S | T | T |  |  |  |  |  |  |  |  |  |  | T | T |
| . | . | . |  |  |  |  |
|
|  | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
|  |  |
| G | G | G | S | S | T | T | S |
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| . | . | . |  |  |  |  |
|
|
| . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
61 | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | |
|
|
. | . | 100 | . | . | . | . | |
|
. | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . |
  |
  |   |
458 | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | I | I | P | H | A | G | T | S | A | Q | T | I | A | T | T | V | K | L | A | K | K | Q | G | K | T | P | I | V | V | R | D | K | A | G | F | Y | V | N | R | I | L | A | P | Y | I | N | E | A | I | R | M | L | T | Q | G | E | R | V | E | H | I | D | A | A | L | V | K | F | G | F | P | V | G | P | I | Q | L | L | D |
Query Conservation |   |
|
|
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |
|
|   |   |   |
|   |
|
|
|
|   |
|
|
|   |   |   |   |   |   |
|
|   |   |
|   |   |
|
|   |   |   |   |   |
|
|   |
|   |   |   |   |
|   |   |   |
|
|
|   |   |   |
|
Alig confidence |   |
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
Template Conservation |   |
|
|
| . | . | . | . | . | . | . |   |   |
|   |   |   |
| . |   |
|   |   |
|   |   |
|   |
|
|
|
|
|
|   |
|
|
|
|
|   |
|   | . | . | . | . | . | . | . | . | . | . | . |   |   |
|   |   |
|   |   |
|
|   |
|
|
|   |
|
|
|
|
| . |   |
|
|
|   |
|
Template Sequence |   |
P | I | I | . |
. |
. |
. |
. |
. |
. |
K | A | L | R | E | G | L | . |
T | A | N | R | I | E | W | L | A | G | I | I | N | G | T | S | N | F | I | L | S | E | X | R | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
D | K | G | A | A | F | D | D | V | L | K | E | A | Q | R | L | G | Y | A | E | . |
A | D | P | T | F | D |
Template Known Secondary structure |   |
|  |  | . | . | . | . | . | . | . |  |  |  |  | T | T | T | . | T | T | S |
|  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  | T | S | S |
| . | S | S |
|  |  |  |
Template Predicted Secondary structure |   |
|  |  | . | . | . | . | . | . | . |  |  |  |  |  |  |  | . |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
| . |
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
136 | . | . | |
|
|
|
|
|
|
. | 140 | . | . | . | . | . | |
. | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | |
190 | . | . | . | . | . |
  |
  |   |
538 | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | V | G | I | D | T | G | T | K | I | I | P | V | L | E | A | A | Y | G | E | R |
Query Conservation |   |
  |   |
|
|
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |
|   |
|
|
|   |
|
|   |
|
|
|   |   |
|
|
|   |   |
Template Sequence |   |
I | E | G | I | D | A | A | H | K | L | T | I | L | S | A | I | A | F | G | I | P |
Template Known Secondary structure |   |
 | T | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
|
Template Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
196 | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . |
  |