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Job DescriptionP77182
Confidence99.44%DateThu Jan 5 12:26:05 GMT 2012
Rank54Aligned Residues374
% Identity14%Templatec2xagA_
PDB info PDB header:transcriptionChain: A: PDB Molecule:lysine-specific histone demethylase 1; PDBTitle: crystal structure of lsd1-corest in complex with para-bromo-2 (-)-trans-2-phenylcyclopropyl-1-amine
Resolution3.10 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   255....260.........270.........280.........290.........300...... ...310.........320......
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Query Sequence  PWFNRTGSSKREAAIIGGGIASALLSLALLRRGWQVTLYCADEAPALGASGN. . . . . . . . RQGALYPLLSKHDEALNRFF
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Template Sequence  RIKPLPTKKTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFRKGNYVADLGAMV. . VTGLGGNPMAVVS
Template Known Secondary structure 
SS


SS




STT

SSSSS
TT

TTSS

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SBT
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   269270.........280.........290.........300.........310.........320.........330... ......340......
 
   327.
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Query Sequence  SN. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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Template Sequence  KQVNMELAKIKQKCPLYEANGQAVPKEKDEMVEQEFNRLLEATSYLSHQLDFNVLNNKPVSLGQALEVVIQLQEKHVKDE
Template Known Secondary structure  TT








TTS
B

TS


TT
B
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   347..350.........360.........370.........380.........390.........400.........410.........420......
 
   329330.........
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . AFTFARRFYDQ
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Template Conservation                                                                                  
Template Sequence  QIEHWKKIVKTQEELKELLNKMVNLKEKIKELHQQYKEASEVKPPRDITAEFLVKSKHRDLTALCKEYDELAETQGKLEE
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SS

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   427..430.........440.........450.........460.........470.........480.........490.........500......
 
   340.........350.........360.........370.........380.........390.........400.........410.........
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Query Sequence  LPVKFDHDWCGVTQLGWDEKSQHKIAQMLSMDLPAELAVAVEANAVEQITGVATNCSGITYPQGGWLCPAELTRNVLELA
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Template Sequence  KLQELEANPPSDVYLSSRDRQILDWHFANLEFANATPLSTLSLKHWDQDDDFEFTGSHLTVRNGYSCVPVAL. . . . . . . .
Template Known Secondary structure  TTS


S
SS
TTTS
TTTBBTTTTTGGGGG

BS

TT
TT........
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   507..510.........520.........530.........540.........550.........560.........570........
 
   420.........430.........440..... ....450.........460.... .....470.......
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Query Sequence  QQQGLQIYYQYQLQNLSRKDDCWLLN. . . . . . FAGDQQATHSVVVLANGHQ. . . . . . . . . . . . . . . . ISRFSQTSTLPVY
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Template Conservation  .     
     
  
                         
 

 
 
   
        
 
 

     

     
Template Sequence  . AEGLDIKLNTAVRQVRYTASGCEVIAVNTRSTSQTFIYKCDAVLCTLPLGVLKQQPPAVQFVPPLPEWKTSAVQRMGFG
Template Known Secondary structure  .TTT


STTSSSTT
S



SS
SSS


S
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   579580.........590.........600.........610.........620.........630.........640.........650.......
 
   478.480.........490......... 500.........510.........520..... ....530.........540........
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Query Sequence  SVAGQVSHIPTTPELAELKQVL. . . . . . . CYDGYLTPQNPANQHHCIGASYHRGS. . EDTAYSEDDQQQNRQRLIDCFPQ
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Template Conservation      
 
 
            
                   
  

     
  
      
  
        
      
Template Sequence  NLNKVVLCFDRVFWDPSVNLFGHVGSTTASRGELFLFWNLYKAPILLALVAGEAAGIMENISDDVIVGRCLAILKGIFGS
Template Known Secondary structure 


SS

S
TT



SSSTTTTTT

SSSS
GGGS

T
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   658.660.........670.........680.........690.........700.........710.........720.........730.......
 
   549550.........560.........570.........580.........590.........600.........610......... 620
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Query Sequence  AQWAKEVDVSDKEARCGVRCATRDHLPMVGNVPDYEATLVEYASLAEQKDEAVSAPVFDDLFMFAALGSRG. . . . . . . . L
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Template Sequence  SAVPQPK. . ETVVSRWRADPWARGSYSYVAAGSSGNDYDLMAQPITPGPSIPGAPQPIPRLFFAGEHTIRNYPATVHGAL
Template Known Secondary structure  TT



S..

TTT
TTTSSS

BTT

TTTTS
B



SSTT







SGGG
TTSTTS
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   738.740.... .....750.........760.........770.........780.........790.........800.........810.....
 
   621........630.........640.
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Query Sequence  CSAPLCAEILAAQMSDEPIPM
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Template Sequence  LSGLREAGRIADQFLGAMYTL
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GGG
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   816...820.........830......
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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