Job Description P0A959 Confidence 99.93% Date Thu Jan 5 11:09:27 GMT 2012 Rank 135 Aligned Residues 335 % Identity 11% Template c3e9kA_ PDB info PDB header:hydrolase Chain: A: PDB Molecule:kynureninase; PDBTitle: crystal structure of homo sapiens kynureninase-3-hydroxyhippuric acid2 inhibitor complex Resolution 1.70 Å

Show / Hide SS confidence

Show / Hide Conservation and Alignment quality

		31	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.											.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100
Predicted Secondary structure																																				.	.	.	.	.	.	.	.	.	.
Query SS confidence																																				.	.	.	.	.	.	.	.	.	.
Query Sequence		E	G	N	K	V	L	K	L	N	I	G	N	P	A	P	F	G	F	D	A	P	D	E	I	L	V	D	V	I	R	N	L	P	T	.	.	.	.	.	.	.	.	.	.	A	Q	G	Y	C	D	S	K	G	L	Y	S	A	R	K	A	I	M	Q	H	Y	Q	A	R	G	M	R	D	V	T	V	E	D	I	Y	I
Query Conservation																																				.	.	.	.	.	.	.	.	.	.
Alig confidence																.	.	.	.																	.	.	.	.	.	.	.	.	.	.																						.	.	.	.	.	.
Template Conservation																.	.	.	.																																																.	.	.	.	.	.
Template Sequence		K	D	E	N	A	I	Y	F	L	G	N	S	L	G	.	.	.	.	L	Q	P	K	M	V	K	T	Y	L	E	E	E	L	D	K	W	A	K	I	A	A	Y	G	H	E	V	G	K	R	P	W	I	T	G	D	E	S	I	V	G	L	M	K	D	I	V	.	.	.	.	.	.	G	A	N	E	K	E	I	A	L
Template Known Secondary structure		T	T		B					B	T	T	T	S		.	.	.	.		B		T	T																G	G	G	G	G	T	S	S	S	S		G	G	G	T	T					G	G	G					.	.	.	.	.	.	T			G	G	G
Template Predicted Secondary structure																.	.	.	.																																																.	.	.	.	.	.
Template SS confidence
		64	.	.	.	.	.	70	.	.	.	.	.	.	.					.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.							.	.	.	.	.	130	.	.	.
		101	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.				.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.										140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.
Predicted Secondary structure																				.	.	.																						.	.	.	.	.	.	.	.	.																											.	.	.
Query SS confidence																				.	.	.																						.	.	.	.	.	.	.	.	.																											.	.	.
Query Sequence		G	N	G	V	S	E	L	I	V	Q	A	M	Q	A	L	L	N	S	.	.	.	G	D	E	M	L	V	P	A	P	D	Y	P	L	W	T	A	A	V	S	L	S	.	.	.	.	.	.	.	.	.	S	G	K	A	V	H	Y	L	C	D	E	S	S	D	W	F	P	D	L	D	D	I	R	A	K	I	.	.	.
Query Conservation																				.	.	.																						.	.	.	.	.	.	.	.	.																											.	.	.
Alig confidence																				.	.	.																						.	.	.	.	.	.	.	.	.														.	.												.	.	.
Template Conservation																																																																		.	.
Template Sequence		M	N	A	L	T	V	N	L	H	L	L	M	L	S	F	F	K	P	T	P	K	R	Y	K	I	L	L	E	A	K	A	F	P	S	D	H	Y	A	I	E	S	Q	L	Q	L	H	G	L	N	I	E	E	S	M	R	M	I	K	P	R	E	G	E	E	.	.	T	L	R	I	E	D	I	L	E	V	I	E	K	E
Template Known Secondary structure			S																		S	S	S							T	T																T	T														T	T		S	.	.	S
Template Predicted Secondary structure																																																																		.	.
Template SS confidence
		134	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.			.	.	200	.	.	.	.	.	.	.	.	.	210	.
		166	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		T	P	R	T	R	G	I	V	I	I	N	P	N	N	P	T	G	A	V	Y	S	K	E	L	L	M	E	I	V	E	I	A	R	Q	H	N	L	I	I	F	A	D	E	I	Y	D	K	I	L	Y	D	D	A	E	H	H	S	I	A	P	L	A	P	D	L	L	T	I	T	F	N	G	L	S	K	T	Y	R	V	A
Query Conservation
Alig confidence																										.	.	.																									.	.	.	.	.	.	.
Template Conservation																										.	.	.																									.	.	.	.	.	.	.
Template Sequence		G	D	S	I	A	V	I	L	F	S	G	V	H	F	Y	T	G	Q	H	F	N	I	P	A	.	.	.	I	T	K	A	G	Q	A	K	G	C	Y	V	G	F	D	L	A	H	A	V	G	N	V	E	.	.	.	.	.	.	.	L	Y	L	H	D	W	G	V	D	F	A	C	W	C	S	Y	K	Y	L	N	A	G
Template Known Secondary structure		G	G	G								S	B		T	T	T		B	B						.	.	.								T	T								T	T	T	T	T	T	S		.	.	.	.	.	.	.							T								S	S	S	T	T
Template Predicted Secondary structure																										.	.	.																									.	.	.	.	.	.	.
Template SS confidence
		212	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.				.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.								260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.
		246	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270																					.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.
Predicted Secondary structure																											.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence																											.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		G	F	R	Q	G	W	M	V	L	N	G	P	K	K	H	A	K	G	Y	I	E	G	L	E	M	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	L	A	S	M	R	L	C	A	N	V	P	A	Q	H	A	I	Q	T	A	L	G	G	Y	Q	S	I	S	E	F	I	T	P	G	G	R
Query Conservation																											.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence																											.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		A	G	G	I	A	G	A	F	I	H	E	K	H	A	H	T	I	K	P	A	L	V	G	W	F	G	H	E	L	S	T	R	F	K	M	D	N	K	L	Q	L	I	P	G	V	C	G	F	R	I	S	N	P	P	I	L	L	V	C	S	L	H	A	S	L	E	I	F	K	Q	A	T	M	K	A	L	R	K	K	S
Template Known Secondary structure		T	T									G	G	G	T	T	T	S			S	S			G	G	G	B						T	T			S				B		S	S	G	G	G	G			S
Template Predicted Secondary structure
Template SS confidence
		282	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.
		306	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330					.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.
Predicted Secondary structure																											.	.	.	.
Query SS confidence																											.	.	.	.
Query Sequence		L	Y	E	Q	R	N	R	A	W	E	L	I	N	D	I	P	G	V	S	C	V	K	P	R	G	.	.	.	.	A	L	Y	M	F	P	K	I	D	A	K	R	F	N	I	H	D	D	Q	K	M	V	L	D	F	L	L	Q	E	K	V	L	L	V	Q	G	T	A	F	N	W	P	W	P	D	H	F	R	I	V	T
Query Conservation																											.	.	.	.
Alig confidence																											.	.	.	.															.	.	.	.	.	.	.													.	.	.	.	.	.
Template Conservation																																													.	.	.	.	.	.	.													.	.	.	.	.	.
Template Sequence		V	L	L	T	G	Y	L	E	Y	L	I	K	H	N	Y	G	V	V	N	I	I	T	P	S	H	V	E	E	R	G	C	Q	L	T	I	T	F	S	V	P	N	K	D	.	.	.	.	.	.	.	V	F	Q	E	L	E	K	R	G	V	V	C	.	.	.	.	.	.	D	K	R	N	P	N	G	I	R	V	A	P
Template Known Secondary structure																							S		S	S	G	G	G	B		S									T	T			.	.	.	.	.	.	.							T	T	T				.	.	.	.	.	.				T	T	T					B
Template Predicted Secondary structure																																													.	.	.	.	.	.	.													.	.	.	.	.	.
Template SS confidence
		362	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.								.	.	.	.	.	410	.	.	.	.	.	.							.	.	.	420	.	.	.	.	.	.	.	.
		382				.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400
Predicted Secondary structure			.	.	.
Query SS confidence			.	.	.
Query Sequence		L	.	.	.	P	R	V	D	D	I	E	L	S	L	S	K	F	A	R	F	L	S
Query Conservation			.	.	.
Alig confidence			.	.	.
Template Conservation
Template Sequence		V	P	L	Y	N	S	F	H	D	V	Y	K	F	T	N	L	L	T	S	I	L	D
Template Known Secondary structure			T	T	T																		T
Template Predicted Secondary structure
Template SS confidence
		438	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.

No model constructed - rank, confidence too low

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions