Job Description P00968 Confidence 100.00% Date Thu Jan 5 10:57:25 GMT 2012 Rank 4 Aligned Residues 382 % Identity 20% Template c1w96B_ PDB info PDB header:ligase Chain: B: PDB Molecule:acetyl-coenzyme a carboxylase; PDBTitle: crystal structure of biotin carboxylase domain of acetyl-2 coenzyme a carboxylase from saccharomyces cerevisiae in3 complex with soraphen a Resolution 1.8 Å

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		5	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.												.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.
Predicted Secondary structure																																										.	.	.	.	.	.	.	.	.	.	.																									.	.	.	.	.
Query SS confidence																																										.	.	.	.	.	.	.	.	.	.	.																									.	.	.	.	.
Query Sequence		T	D	I	K	S	I	L	I	L	G	A	G	P	I	V	I	G	Q	A	C	E	F	D	Y	S	G	A	Q	A	C	K	A	L	R	E	E	G	Y	R	V	.	.	.	.	.	.	.	.	.	.	.	I	L	V	N	S	N	P	A	T	I	M	T	D	P	E	M	A	D	A	T	Y	I	E	P	.	.	.	.	.
Query Conservation																																										.	.	.	.	.	.	.	.	.	.	.																									.	.	.	.	.
Alig confidence																		.	.	.	.	.	.	.	.	.	.	.														.	.	.	.	.	.	.	.	.	.	.																									.	.	.	.	.
Template Conservation																		.	.	.	.	.	.	.	.	.	.	.
Template Sequence		T	V	I	S	K	I	L	I	A	N	N	G	I	A	A	V	.	.	.	.	.	.	.	.	.	.	.	K	E	I	R	S	V	R	K	W	A	Y	E	T	F	G	D	D	R	T	V	Q	F	V	A	M	A	T	P	E	D	L	E	A	N	A	E	Y	I	R	M	A	D	Q	Y	I	E	V	P	G	G	T	N	N
Template Known Secondary structure		B																.	.	.	.	.	.	.	.	.	.	.															S		T	T	S	S													T	T							S	S								S	S	G	G
Template Predicted Secondary structure																		.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		57	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.												.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.
					69	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.
Predicted Secondary structure		.	.	.
Query SS confidence		.	.	.
Query Sequence		.	.	.	I	H	W	E	V	V	R	K	I	I	E	K	E	R	P	D	A	V	L	P	T	M	G	G	Q	T	A	L	N	C	A	L	E	L	E	R	Q	G	V	L	E	E	F	G	V	T	M	I	G	A	T	A	D	A	I	D	K	A	E	D	R	R	R	F	D	V	A	M	K	K	I	G	L	E	T	A	R
Query Conservation		.	.	.
Alig confidence		.	.	.																								.	.	.
Template Conservation																												.	.	.
Template Sequence		N	N	Y	A	N	V	D	L	I	V	D	I	A	E	R	A	D	V	D	A	V	W	A	G	W	G	.	.	.	H	A	S	E	N	P	L	L	P	E	K	L	S	Q	S	K	R	K	V	I	F	I	G	P	P	G	N	A	M	R	S	L	G	D	K	I	S	S	T	I	V	A	Q	S	A	K	V	P	C	I	P
Template Known Secondary structure		G	T	T	T												T	T		S						S	S	.	.	.	T	T	T	T		T									S	T	T					S	S									S		S											T	T			B
Template Predicted Secondary structure																												.	.	.
Template SS confidence
		126	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.				.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.
		146	.																											.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.
Predicted Secondary structure				.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence				.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		S	G	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	I	A	H	T	M	E	E	A	L	A	V	A	A	D	V	G	F	P	C	I	I	R	P	S	F	T	M	G	G	S	G	G	G	I	A	Y	N	R	E	E	F	E	E	I	C	A	R	G	L	D	L	S
Query Conservation				.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence				.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		W	S	G	T	G	V	D	T	V	H	V	D	E	K	T	G	L	V	S	V	D	D	D	I	Y	Q	K	G	C	C	T	S	P	E	D	G	L	Q	K	A	K	R	I	G	F	P	V	M	I	K	A	S	E	G	G	G	G	K	G	I	R	Q	V	E	R	E	E	D	F	I	A	L	Y	H	Q	A	A	N	E	I
Template Known Secondary structure		B	T	T	T	T								T	T	T											G	G	G	S		S	S													S	S						T	T			S	S	T	T					S	S	G	G	G												S
Template Predicted Secondary structure
Template SS confidence
		203	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.
		200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		P	T	K	E	L	L	I	D	E	S	L	I	G	W	K	E	Y	E	M	E	V	V	R	D	K	N	D	N	C	I	I	V	C	S	I	E	N	F	D	A	M	G	I	H	T	G	D	S	I	T	V	A	P	A	Q	T	L	T	D	K	E	Y	Q	I	M	R	N	A	S	M	A	V	L	R	E	I	G	V	E	T
Query Conservation
Alig confidence																																			.	.																																													.
Template Conservation																																			.	.																																													.
Template Sequence		P	G	S	P	I	F	I	M	K	L	A	G	R	A	R	H	L	E	V	Q	L	L	A	D	Q	Y	G	T	N	I	S	L	F	.	.	G	R	D	C	S	V	Q	R	R	H	Q	K	I	I	E	E	A	P	V	T	I	A	K	A	E	T	F	H	E	M	E	K	A	A	V	R	L	G	K	L	V	G	Y	V	.
Template Known Secondary structure		T	T											S												T	T	S							.	.									T	T								S			S	S																				T			.
Template Predicted Secondary structure																																			.	.																																													.
Template SS confidence
		283	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.			.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.
		280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.
Predicted Secondary structure																																																																		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence																																																																		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		G	G	S	N	V	Q	F	A	V	N	P	K	N	G	R	L	I	V	I	E	M	N	P	R	V	S	R	S	S	A	L	A	S	K	A	T	G	F	P	I	A	K	V	A	A	K	L	A	V	G	Y	T	L	D	E	L	M	N	D	I	T	G	G	R	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Conservation																																																																		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence																																																																		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		S	A	G	T	V	E	Y	L	Y	S	H	D	D	G	K	F	Y	F	L	E	L	N	P	R	L	Q	V	E	H	P	T	T	E	M	V	S	G	V	N	L	P	A	A	Q	L	Q	I	A	M	G	I	P	M	H	R	I	S	D	I	R	T	L	Y	G	M	N	P	H	S	A	S	E	I	D	F	E	F	K	T	Q
Template Known Secondary structure												T	T	T	T										S			T	T	T																				T	T			G	G	G								T	T			T	T							T	T			S
Template Predicted Secondary structure
Template SS confidence
		360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.
				344	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360									.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.								380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.
Predicted Secondary structure		.	.																		.	.	.	.	.	.	.	.																				.	.	.	.	.	.	.
Query SS confidence		.	.																		.	.	.	.	.	.	.	.																				.	.	.	.	.	.	.
Query Sequence		.	.	T	P	A	S	F	E	P	S	I	D	Y	V	V	T	K	I	P	.	.	.	.	.	.	.	.	R	F	N	F	E	K	F	A	G	A	N	D	R	L	T	T	Q	M	K	.	.	.	.	.	.	.	S	V	G	E	V	M	A	I	G	R	T	Q	Q	E	S	L	Q	K	A	L	R	G	L	E
Query Conservation		.	.																		.	.	.	.	.	.	.	.																				.	.	.	.	.	.	.
Alig confidence		.	.																		.	.	.	.	.	.	.	.																				.	.	.	.	.	.	.
Template Conservation
Template Sequence		D	A	T	K	K	Q	R	R	P	I	P	K	G	H	C	T	A	C	R	I	T	G	T	L	H	E	L	N	F	R	S	S	S	N	V	W	G	Y	F	S	V	G	N	N	G	N	I	H	S	F	S	D	S	Q	F	G	H	I	F	A	F	G	E	N	R	Q	A	S	R	K	H	M	V	V	A	L	K
Template Known Secondary structure														S																	S	S		S	S									T	T		S	S		S	S		S											S	S
Template Predicted Secondary structure
Template SS confidence
		440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.