|   |
558 | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | |
|
|
580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . | . | . | . | . | . | . | 610 | . | . | . | . | . | . | . | . | . | 620 | . | . | . | . | . | . | . | . | . | 630 | . | . | |
|
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
Query Sequence |   |
D | R | E | K | I | M | V | L | G | G | G | P | N | R | I | G | Q | G | I | E | F | D | . |
. |
. |
Y | C | C | V | H | A | S | L | A | L | R | E | D | G | Y | E | T | I | M | V | N | C | N | P | E | T | V | S | T | D | Y | D | T | S | D | R | L | Y | F | E | P | V | T | L | E | D | V | L | E | I | V | R | I | . |
. |
Query Conservation |   |
  |   |   |
|
|
|
|
|
|
|
|   |   |
|
|
|   |   |   |
|
|
| . | . | . |
|   |   |
|   |   |
|   |
|
|
|   |   |
|   |   |
|
|   |
|
|   |
|
|
|
|
|
|
|
|
|
|   |
|
|   |
|
|
|
|
|
|   |   |
|   |
|
|   |
|   |   |   | . | . |
Alig confidence |   |
|
|
|
|
|
|
|
|
| . |
| . | . | . | . |
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
Template Conservation |   |
  |
|   |
|
|   |
|
|   | . |
| . | . | . | . |
|   |   |   |
|   |   |
|
|
|   |
|
|   |   |
|   |   |
|
|   |   |   |
|   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
N | R | I | K | V | A | I | L | F | . |
G | . |
. |
. |
. |
G | C | S | E | E | H | D | V | S | V | K | S | A | I | E | I | A | A | N | I | N | K | E | K | Y | E | P | L | Y | I | G | I | T | K | S | G | V | W | K | M | C | E | K | P | C | A | E | W | E | N | E | N | C | Y | S | A | V | L | S | P | D | K | K | M | H |
Template Known Secondary structure |   |
|
|  |  |  |  |  |  |  | . |  | . | . | . | . |
| S | S | T | T |  |  |  |  |  |  |  |  |  |  |  |  | T | T | S |
| T | T | T |  |  |  |  |  |  |  |  |
| T | T | S |
|  |  |  |  | S | S |
| S | T | T |
|
|
| T | T |
|  |  |  |  |  |
|
|
| T | T | T |
|
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  | . |
| . | . | . | . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|  |  |
|
|
|
|
|
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
2 | . | . | . | . | . | . | . | 10 | |
. | |
|
|
|
. | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . |
  |
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
633 | . | . | . | . | . | . | 640 | . | . | . | . | . | . | . | . | |
|
. | 650 | . | . | . | . | . | . | . | . | . | 660 | . | . | . | . | . | . | . | . | . | 670 | . | . | . | . | . | . | . | . | . | 680 | . | . | . | . | . | . | . | . | . | 690 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  | . | . |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |
|
|  |
Query SS confidence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
E | K | P | K | G | V | I | V | Q | Y | G | G | Q | T | P | L | . |
. |
K | L | A | R | A | L | E | A | A | G | V | P | V | I | G | T | S | P | D | A | I | D | R | A | E | D | R | E | R | F | Q | H | A | V | E | R | L | K | L | K | Q | P | A | N | A | T | V | T | A | I |
Query Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . |
|   |   |
|
|
|
|   |   |   |
|
|
|   |   |   | . | . |   |
|
|   |   |
|
|   |   |
|
|   |
|
|
|   |
|   |   |
|
|   |   |
|   |
|
|   |   |   |
|   |   |
|   |   |   |
|
|
|   |
|   |   |   |   |   |   |
|   |
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |
|   |   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |
Template Sequence |   |
G | L | L | V | K | K | N | H | E | Y | E | I | N | H | V | D | V | A | F | S | A | L | H | G | K | S | G | E | D | G | S | I | Q | G | L | F | E | L | S | G | I | P | F | V | G | C | D | I | Q | S | S | A | I | C | M | D | K | S | L | T | Y | I | V | A | K | N | A | G | I | A | T | P | A | F | W | V | I | N | K | D |
Template Known Secondary structure |   |
 |  |  |  |  | S | S | S | S |  |  |  |  |  |
| S |  |  |  |  |
|
|
| S | T | T | T | T | S | S |  |  |  |  |  |  |  |  |  | T |
|
| B | S | S |
|
|  |  |  |  |  |  |  |  | S |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
|
|
|  |  |  |  |
| S | S |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |
|
|
|  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |
|
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
77 | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . |
  |
  |   |
699 | 700 | . | . | . | . | . | . | . | . | . | 710 | . | . | . | . | . | . | . | . | . | 720 | . | . | . | . | . | . | . | . | . | 730 | . | . | . | . | . | . | . | . | . | 740 | . | . | . | . | . | . | . | . | . | 750 | . | . | . | . | . | . | . | . | . | 760 | . | . | . | . | . | . | . | . | . | 770 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | M | A | V | E | K | A | K | E | I | G | Y | P | L | V | V | R | P | S | Y | V | L | G | G | R | A | M | E | I | V | Y | D | E | A | D | L | R | R | Y | F | Q | T | A | V | S | V | S | N | D | A | P | V | L | L | D | H | F | L | D | D | A | V | E | V | D | V | D | A | I | C | D | G | E | M | V | L | I | G | G | I |
Query Conservation |   |
|
|
|   |   |   |
|   |   |
|
|
|
|
|
|
|
|
|
|   |   |   |
|
|   |
|
|   |
|
|   |   |   |   |
|
|   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |
|
|
|
|
|
|
|
|   |
|   |
|
|
|
|
|   |
|   |
|   |   |   |
|   |
|   |   |
|
Alig confidence |   |
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   | . | . |   |   |   |   |   |   |   |
|   |
|   |
|
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . |   |   |   |   |
|
|
|   |
|   | . |
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
D | R | P | . |
. |
V | A | A | T | F | T | Y | P | V | F | V | K | P | A | R | S | G | S | S | F | G | V | K | K | V | N | S | A | D | E | L | D | Y | A | I | E | S | A | R | Q | Y | D | . |
. |
S | K | I | L | I | E | Q | A | V | S | . |
G | C | E | V | G | C | A | V | L | G | N | S | A | A | L | V | V | G | E | V |
Template Known Secondary structure |   |
|
|
| . | . |
| G | G | G | S |
| S | S |  |  |  |  |  | S | S |
|
| T | T | T | T |
|  |  |  |
| S | G | G | G |  |  |  |  |  |  |  |  | T | T | T |
| . | . | S | S |  |  |  |  |  |
|
|
| . | S |  |  |  |  |  |  |  |  |  |
| T | T |
|
|  |  |
|
|
|
Template Predicted Secondary structure |   |
 |  |  | . | . |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
| . | . |
|
|  |  |  |  |  |  |  |
| . |
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
157 | . | . | |
|
160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | |
|
. | . | . | . | . | . | . | . | 210 | . | |
. | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . |
  |
  |   |
779 | 780 | . | . | . | . | . | . | . | . | . | 790 | . | . | |
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | 800 | . | . | . | . | . | . | . | . | . | 810 | . | . | . | . | . | . | . | . | . | 820 | . | . | . | . | . | . | . | . | . | 830 | . | . | . | |
. | . | . | . | . | . | 840 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|
|
|
|
|  | . | . | . | . | . | . | . | . | . | . |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  | . |
|
|  |  |  |  |  |  |  |  |
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
M | E | H | I | E | Q | A | G | V | H | S | G | D | S | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
A | C | S | L | P | A | Y | T | L | S | Q | E | I | Q | D | V | M | R | Q | Q | V | Q | K | L | A | F | E | L | Q | V | R | G | L | M | N | V | Q | F | A | V | K | . |
N | N | E | V | Y | L | I | E | V | N | P | R | A | A |
Query Conservation |   |
  |
|   |   |
|   |   |
|   |
|
|
|
|   | . | . | . | . | . | . | . | . | . | . |   |   |   |   |
|
|   |   |
|   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|
|   |
|
|
|   |   |
|   |   |
|
|
|
|   |
|   | . |
|   |   |   |
|
|
|
|
|
|
|
|   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |
|
|   |   |
|   |   |   |
|
|   |   |   |   |   |   |
|   |   |   |
|
|
|
|
|   |   |
|
|
Template Sequence |   |
D | Q | I | R | L | Q | Y | G | I | F | R | I | H | Q | E | V | E | P | E | K | G | S | E | N | A | V | I | T | V | P | A | D | L | S | A | E | E | R | G | R | I | Q | E | T | V | K | K | I | Y | K | T | L | G | C | R | G | L | A | R | V | D | M | F | L | Q | D | R | G | R | I | V | L | N | E | V | N | T | L | P | G |
Template Known Secondary structure |   |
 |  |  |  |  | S | S | S |
|
|
| G | G | G | S | S | S | G | G | G |
|
| S | S |  |  |  |  | S | S |
| S | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|  |  |  |  |  |  |  |  |  |
| T | T |
|
|  |  |  |  |  |  |  | S | S |
|
|
Template Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
232 | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . |
  |
  |   |
848 | . | |
|
|
|
850 | . | . | . | . | . | . | . | . | . | 860 | . | . | . | . | |
|
|
. | . | . | . | . | 870 |
Predicted Secondary structure |   |
|
| . | . | . | . |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  | . | . | . |  |  |  |  |  |
|
Query SS confidence |   |
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
Query Sequence |   |
R | T | . |
. |
. |
. |
V | P | F | V | S | K | A | T | G | V | P | L | A | K | V | . |
. |
. |
A | A | R | V | M | A |
Query Conservation |   |
|
| . | . | . | . |   |
|   |
|
|
|   |
|
|   |
|
|
|   |   | . | . | . |
|   |   |
|   |
|
Alig confidence |   |
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|
|   |   |
|
|   |   |
|   |
Template Sequence |   |
F | T | S | Y | S | R | Y | P | R | M | M | A | A | A | G | I | S | L | P | E | L | I | D | R | L | I | V | L | A | L |
Template Known Secondary structure |   |
| S | T | T |
|  |  |  |  |  |  |  |  | T | T |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
Template Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
312 | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . |
  |