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Job DescriptionP76176
Confidence99.97%DateThu Jan 5 12:20:09 GMT 2012
Rank36Aligned Residues222
% Identity20%Templatec1ghwH_
PDB info PDB header:hydrolase/hydrolase inhibitorChain: H: PDB Molecule:thrombin; PDBTitle: a novel serine protease inhibition motif involving a multi-centered2 short hydrogen bonding network at the active site
Resolution1.75 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   38.40.........50.........60.........70.........80.........90.........100.........110.......
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Query Sequence  FFGHDDRVPVNDTTQSPWDAVGQLETASGNLCTATLIAPNLALTAGHCLLTPPKGKADKAVALRFVSNKGLWRYEIHDIE
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Template Sequence  IVEGSD. . . . AEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIE
Template Known Secondary structure 
BS
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TTSSTTTTTT
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GGGTGGGT

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BSSS

TTT
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   16...20. ........30.........40.........50.........60.........70.........80.........90.
 
   118.120.........130.........140.........150...... ...160........ .170.........180.........190
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Query Sequence  GRVDPTLGKRLKADGDGWIVPPAAAPWDFGLIVLRNPPS. . . GITPLPLFEGDK. . . . AALTAALKAAGRKVTQAGYPED
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Template Sequence  KIS. . . . . MLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETGQPS
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TT
BTTTT
BT

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B




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S
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   81.. ......90.........100.........110.........120.........130.........140.........150.....
 
   191........ 200.........210.........220.........230. ........240.........250....
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Query Sequence  HLDTLYSHQ. . . . . . . . . . . . . . NCEVTGWAQTSVMSHQCDTLPGDSGSPLMLHT. . DDGWQLIGVQSSAPAAKDRWRAD
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Template Sequence  VLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKY.
Template Known Secondary structure  B
B

TT
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TT


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B

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   154.....160.........170.........180.........190.........200.........210.........220.........230..
 
   255....260.........
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Query Sequence  NRAISVTGFRDKLDQ
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Template Sequence  GFYTHVFRLKKWIQK
Template Known Secondary structure  TGGG
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   226...230.........240
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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