Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	R	T	V	L	N	I	L	N	F	V	L	G	G	F	A	T	T	L	G	W	L	L	A	T	L	V	S	I	V	L	I	F	T	L	P	L	T	R	S	C	W	E	I	T	K	L	S	L	V	P	Y	G	N	E	A	I	H	V	D
Secondary structure
SS confidence
Disorder		?	?																																																						?		?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		E	L	N	P	A	G	K	N	V	L	L	N	T	G	G	T	V	L	N	I	F	W	L	I	F	F	G	W	W	L	C	L	M	H	I	A	T	G	I	A	Q	C	I	S	I	I	G	I	P	V	G	I	A	N	F	K	I	A	A	I
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.
Sequence		A	L	W	P	V	G	R	R	V	V	S	V	E	T	A	Q	A	A	R	E	A	N	A	R	R	R	F	E
Secondary structure
SS confidence
Disorder														?	?	?	?	?	?	?	?					?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1n7v chain A Region: 121 - 141 Aligned: 21 Modelled: 21 Confidence: 17.9% Identity: 24% Fold: Adsorption protein p2 Superfamily: Adsorption protein p2 Family: Adsorption protein p2 Phyre2 PDB 3kys chain C Region: 125 - 144 Aligned: 20 Modelled: 20 Confidence: 10.1% Identity: 35% PDB header:transcription/protein binding Chain: C: PDB Molecule:transcriptional enhancer factor tef-1; PDBTitle: crystal structure of human yap and tead complex Phyre2 PDB 3l15 chain A Region: 125 - 144 Aligned: 20 Modelled: 20 Confidence: 9.2% Identity: 25% PDB header:transcription Chain: A: PDB Molecule:transcriptional enhancer factor tef-4; PDBTitle: human tead2 transcriptional factor Phyre2 PDB 2bbg chain A Region: 116 - 134 Aligned: 19 Modelled: 19 Confidence: 7.3% Identity: 21% Fold: Amb V allergen Superfamily: Amb V allergen Family: Amb V allergen Phyre2 PDB 2cpb chain A Region: 18 - 43 Aligned: 26 Modelled: 26 Confidence: 7.0% Identity: 8% PDB header:viral protein Chain: A: PDB Molecule:m13 major coat protein; PDBTitle: solution nmr structures of the major coat protein of2 filamentous bacteriophage m13 solubilized in3 dodecylphosphocholine micelles, 25 lowest energy structures Phyre2 PDB 2knc chain A Region: 88 - 116 Aligned: 29 Modelled: 29 Confidence: 6.8% Identity: 17% PDB header:cell adhesion Chain: A: PDB Molecule:integrin alpha-iib; PDBTitle: platelet integrin alfaiib-beta3 transmembrane-cytoplasmic2 heterocomplex Phyre2 PDB 3lu2 chain B Region: 49 - 59 Aligned: 11 Modelled: 11 Confidence: 5.7% Identity: 36% PDB header:hydrolase Chain: B: PDB Molecule:lmo2462 protein; PDBTitle: structure of lmo2462, a listeria monocytogenes amidohydrolase family2 putative dipeptidase Phyre2 PDB 1itu chain A Region: 49 - 59 Aligned: 11 Modelled: 11 Confidence: 5.2% Identity: 27% Fold: TIM beta/alpha-barrel Superfamily: Metallo-dependent hydrolases Family: Renal dipeptidase Phyre2 1 d1n7va_ 2 c3kysC_ 3 c3l15A_ 4 d2bbga_ 5 c2cpbA_ 6 c2kncA_ 7 c3lu2B_ 8 d1itua_

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d1n7va_ 17.9 24 Fold:Adsorption protein p2 Superfamily:Adsorption protein p2 Family:Adsorption protein p2 2 c3kysC_ 10.1 35 PDB header:transcription/protein binding Chain: C: PDB Molecule:transcriptional enhancer factor tef-1; PDBTitle: crystal structure of human yap and tead complex 3 c3l15A_ 9.2 25 PDB header:transcription Chain: A: PDB Molecule:transcriptional enhancer factor tef-4; PDBTitle: human tead2 transcriptional factor 4 d2bbga_ 7.3 21 Fold:Amb V allergen Superfamily:Amb V allergen Family:Amb V allergen 5 c2cpbA_ 7.0 8 PDB header:viral protein Chain: A: PDB Molecule:m13 major coat protein; PDBTitle: solution nmr structures of the major coat protein of2 filamentous bacteriophage m13 solubilized in3 dodecylphosphocholine micelles, 25 lowest energy structures 6 c2kncA_ 6.8 17 PDB header:cell adhesion Chain: A: PDB Molecule:integrin alpha-iib; PDBTitle: platelet integrin alfaiib-beta3 transmembrane-cytoplasmic2 heterocomplex 7 c3lu2B_ 5.7 36 PDB header:hydrolase Chain: B: PDB Molecule:lmo2462 protein; PDBTitle: structure of lmo2462, a listeria monocytogenes amidohydrolase family2 putative dipeptidase 8 d1itua_ 5.2 27 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Renal dipeptidase

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0