|   |
52 | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | |
. | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  | . |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
P | T | R | D | V | V | Q | R | A | L | A | E | L | E | G | G | A | G | A | V | L | T | N | T | G | M | S | A | I | H | L | V | T | T | V | F | L | K | P | G | D | L | . |
L | V | A | P | H | D | C | Y | G | G | S | Y | R | L | F | D | S | L | A | K | R | G | C | Y | R | V | L | F | V | D | Q | G | D | E | Q | A | L |
Query Conservation |   |
|   |   |   |   |
|
|   |   |   |
|   |   |   |
|   |
|   |   |
|   |   |   |
|
|   |   |
|
|   |   |   |
|   |
|
|   |   |   |
|
|   | . |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|   |   |   |
|   |   |   |   |
|   |   |   |   |   |
|
|   |   |   |   |   |   |
|
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . |   |   |   |   |   |   |   |   |
|   |   |   |
Template Sequence |   |
E | K | V | N | E | Y | G | L | K | H | L | G | G | D | E | N | D | K | C | V | G | F | N | R | T | S | S | A | I | L | A | T | I | L | A | L | K | P | K | K | V | I | H | Y | L | P | E | L | P | G | H | P | S | I | E | R | S | C | K | I | V | N | . |
. |
. |
. |
. |
. |
A | K | Y | F | E | S | D | K | V | G | E | I |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  | T |
|
| T | T |  |  |  |  |  |  | S | S |  |  |  |  |  |  |  |  |  |  |  |  |
|
| S |  |  |  |  |  |
| S | S | S | S |
|
| T |  |  |  |  |  |  |  |  | T | T | . | . | . | . | . | . |
|  |  |  |  |  | S |
|  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
| . | . | . | . | . | . |
|  |  |
|
|
|
|
|  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
61 | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | |
|
|
|
|
|
. | . | . | . | . | . | . | 130 | . | . | . | . |
  |
  |   |
131 | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | |
|
|
. | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | |
|
|
|
|
. | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . |
Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|  |  | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
R | A | A | L | A | E | K | P | K | L | V | L | V | E | S | P | S | N | P | L | L | R | V | . |
. |
. |
V | D | I | A | K | I | C | H | L | A | R | E | V | G | A | V | S | V | V | D | N | T | F | L | S | P | A | L | Q | N | . |
. |
. |
. |
. |
P | L | A | L | G | A | D | L | V | L | H | S | C | T | K | Y | L | N | G |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |
|   |   | . | . | . |   |   |
|   |   |
|   |   |
|
|   |   |   |
|   |   |
|
|
|
|   |
|   |
|   |
|   |   |   |   | . | . | . | . | . |   |   |   |   |
|   |
|   |   |   |   |
|   |   |
|   |   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |   |   |   |   |   | . | . |   |   |
|   |   |
|   |
|
|
|
|   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
Template Sequence |   |
L | N | K | I | D | K | D | T | . |
. |
L | V | I | I | T | G | S | T | M | D | L | K | V | I | E | L | E | N | F | K | K | V | I | N | T | A | K | N | K | E | A | I | V | F | V | D | D | A | S | G | A | R | V | R | L | L | F | N | Q | P | P | A | L | K | L | G | A | D | L | V | V | T | S | T | D | K | L | M | E | G |
Template Known Secondary structure |   |
 | T | T |
|
| T | T |  | . | . |  |  |  |  |  |
| B |
| T | T | S |
| B |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
|  |  |  |  |
| T | T |  |  |  |  |  |  |  | T | T |
|
|
|  |  |  |  | T |
| S |  |  |  |  |  | T | T | S | S | S | S | S |
Template Predicted Secondary structure |   |
 |  |  |
|
|
|
|
| . | . |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
135 | . | . | . | . | 140 | . | . | |
|
. | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . |
  |
  |   |
203 | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . |
Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
H | S | D | V | V | A | G | V | V | I | A | K | D | P | D | V | V | T | E | L | A | W | W | A | N | N | I | G | V | T | G | G | A | F | D | S | Y | L | L | L | R | G | L | R | T | L | V | P | R | M | E | L | A | Q | R | N | A | Q | A | I | V | K | Y | L | Q | T | Q | P | L | V | K | K | L | Y | H | P | S | L | P | E |
Query Conservation |   |
  |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |
|   |   |   |
| . | . | . | . |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
Template Sequence |   |
P | R | G | G | L | L | A | G | . |
. |
. |
. |
K | K | E | L | V | D | K | I | Y | I | E | G | T | K | F | G | L | E | A | Q | P | P | L | L | A | G | I | Y | R | A | L | K | N | F | . |
. |
. |
. |
. |
N | L | E | R | I | R | K | A | F | E | R | A | K | N | F | D | L | S | K | I | E | K | L | N | K | E | L | K | A |
Template Known Secondary structure |   |
| S |
|  |  |  |  |  | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | T |
| B |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
| . | . | . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  | T | T |
Template Predicted Secondary structure |   |
|
|  |  |  |
|
|
| . | . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
213 | . | . | . | . | . | . | 220 | |
|
|
|
. | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | |
|
|
|
|
. | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . |
  |
  |   |
283 | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | |
|
|
|
. | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  | . | . | . | . |  |  |  |  |  |
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
N | Q | G | H | E | I | A | A | R | Q | Q | K | G | F | G | A | M | L | S | F | E | L | D | G | D | E | Q | T | L | R | R | F | L | . |
. |
. |
. |
G | G | L | S | L | F | T | L | A | E | S | L | G | G | V | E | S | L | I | S | H | A | A | T | M | T | H | A | G | M | A | P | E | A | R | A | A | A | G | I | S | E | T |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   | . | . | . | . |   |   |
|   |   |   |   |
|   |   |
|   |
|   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
|   |   |   |
|
|   |   |
|
|   |   |   |   |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |
Template Sequence |   |
I | D | D | N | I | N | I | V | Y | E | R | T | P | T | G | F | V | I | K | R | V | Y | K | D | D | T | I | N | I | K | K | L | I | E | I | G | F | N | L | L | K | N | Y | G | I | I | T | I | T | V | A | G | M | P | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
G | A | S | K |
Template Known Secondary structure |   |
T |
| T | T |  |  |  |  |  |  |  |
| S | S |  |  |  |  |  |  |  |  | S | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  |  |
| S | T | T | S | S | S |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | S | S |
|
|
Template Predicted Secondary structure |   |
 |  |  |  |
|
|
|  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
284 | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | 340 | . |
  |
  |   |
359 | 360 | . | . | . | . | . | |
|
|
|
|
. | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  | . | . | . | . | . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | L | R | I | S | T | G | . |
. |
. |
. |
. |
I | E | D | G | E | D | L | I | A | D | L | E | N | G | F | R | A | A | N | K |
Query Conservation |   |
  |
|
|
|
|
|
| . | . | . | . | . |   |
|   |   |   |
|
|
|   |   |
|   |   |
|
|   |
|   |   |   |
Alig confidence |   |
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|
|
|
|   |   |   |   |   |   |   |
|   |
|
|
|   |
|
|   |
|
|   |
|   |
|
|   |   |   |   |
Template Sequence |   |
S | L | R | I | D | L | T | S | R | D | A | E | R | I | D | D | N | Y | I | I | K | A | I | V | E | S | I | K | M | A | F | K |
Template Known Secondary structure |   |
S |  |  |  |  | T | T | S | G | G | G | G | G | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
342 | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . |
  |