|   |
40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
. | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . | . | . | . | . | . | . | . |
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | P | R | A | H | D | Y | S | R | R | G | N | P | T | R | D | V | V | Q | R | A | L | A | E | L | E | G | . |
. |
. |
. |
. |
. |
. |
. |
G | A | G | A | V | L | T | N | T | G | M | S | A | I | H | L | V | T | T | V | F | L | K | P | G | D | L | L | V | A | P | H | D | C | Y | G | G | S | Y | R | L | F | D | S | L |
Query Conservation |   |
  |   |   |   |   |   |
|   |
|   |   |   |
|   |   |   |   |
|
|   |   |   |
|   |   |   |
| . | . | . | . | . | . | . | . |   |
|   |   |
|   |   |   |
|
|   |   |
|
|   |   |   |
|   |
|
|   |   |   |
|
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |
|   |   |   |   |   |   | . | . | . |   |
|
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
M | H | G | V | F | G | Y | S | R | W | K | N | D | . |
. |
. |
E | F | L | A | A | I | A | H | W | F | S | T | Q | H | Y | T | A | I | D | S | Q | T | V | V | Y | G | P | S | V | I | Y | M | V | S | E | L | I | R | Q | W | S | E | T | G | E | G | V | V | I | H | T | P | A | Y | D | A | F | Y | K | A | I | E | G | N |
Template Known Secondary structure |   |
T | T |
|
|
|
|
|
|
| S |
|
|  | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  | S |
|
|
|
|
| G | G | G |  |  |  |  | S |
|  |  |  |  |  |  |  |  |  |  |  | S | S |
| T | T |
|  |  |  |  |  |  | S |
|
|  |  |  |  |  |  |  |  |  | T |
Template Predicted Secondary structure |   |
 |
|
|
|
|
|
|
|
|
|
|
|  | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
55 | . | . | . | . | 60 | . | . | . | . | . | . | . | |
|
|
. | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . |
  |
  |   |
112 | . | . | . | . | . | . | . | 120 | . | . | . | . | . | |
|
|
|
. | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | |
|
|
|
. | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . |
Predicted Secondary structure |   |
 |
|
|
|
|  |  |  |  |  |
|
|
|
| . | . | . | . |
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
| . | . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | K | R | G | C | Y | R | V | L | F | V | D | Q | G | . |
. |
. |
. |
D | E | Q | A | L | R | A | A | L | A | E | K | P | K | L | V | L | V | E | S | P | S | N | P | L | . |
. |
. |
. |
L | R | V | V | D | I | A | K | I | C | H | L | A | R | E | V | G | A | V | S | V | V | D | N | T | F | L | S | P | A | L | Q | N |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |
|   |   | . | . | . | . |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   | . | . | . | . |
|   |   |   |   |
|   |   |
|   |   |
|
|   |   |   |
|   |   |
|
|
|
|   |
|   |
|   |
|   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
Q | R | T | V | M | P | V | A | L | E | K | Q | A | D | G | W | F | C | D | M | G | K | L | E | A | V | L | A | K | P | E | C | K | I | M | L | L | C | S | P | Q | N | P | T | G | K | V | W | T | C | D | E | L | E | I | M | A | D | L | C | E | R | H | G | V | R | V | I | S | D | E | I | H | M | D | M | V | W | G | E |
Template Known Secondary structure |   |
T |
|  |  |  |  |  |  |
|  |  |
| S | S | S |  |  |
|
|  |  |  |  |  |  |  |  | T | S | T | T |  |  |  |  |  |  |  | S | S |
| T | T | T |
|
|
|
|
| T | T |  |  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |
| T | T | T | T |
| B |
| S | S |
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
132 | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . |
  |
  |   |
184 | . | |
|
|
|
|
|
|
. | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  | . | . | . | . | . | . | . |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
| . |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
P | L | . |
. |
. |
. |
. |
. |
. |
A | L | G | A | D | L | V | L | H | S | C | T | K | Y | L | N | G | H | S | D | V | V | A | G | V | V | I | A | K | D | P | D | V | V | T | E | L | A | W | W | A | N | N | I | G | V | T | G | G | A | F | D | S | Y | L | L | L | R | G | L | R | T | L | V | P | R | M | E | L | A | Q |
Query Conservation |   |
  |   | . | . | . | . | . | . | . |   |   |
|   |
|   |   |   |   |
|   |   |
|   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|   |   |   |   |   | . |
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
Q | P | H | I | P | W | S | N | V | A | R | G | D | W | A | L | L | T | S | G | S | K | S | F | N | I | P | . |
A | L | T | G | A | Y | G | I | I | E | N | S | S | S | R | D | A | Y | L | S | A | L | K | G | R | D | G | L | . |
S | S | P | S | V | L | A | L | T | A | H | I | A | A | Y | Q | Q | G | A | P | W | L | D |
Template Known Secondary structure |   |
S |
|
|
|
| G | G | G | T |
|
| S | S |  |  |  |  |  |
| S |  |  |  |  | T |
| G | . | G | G |
|
|  |  |  |  |  |
| S |  |  |  |  |  |  |  |  |  |  |  |  | T | T | S |
|
| . |
| S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  | . |  |  |
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
| . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
212 | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | |
. | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | |
. | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . |
  |
  |   |
257 | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | |
. | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  | . |  |  |
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
R | N | A | Q | A | I | V | K | Y | L | Q | T | Q | P | L | V | K | K | L | Y | H | P | S | L | P | E | N | Q | G | H | E | I | A | A | R | Q | Q | K | G | F | G | A | M | L | S | F | E | L | D | G | D | E | Q | T | L | R | R | F | L | G | G | L | . |
S | L | F | T | L | A | E | S | L | G | G | V | E | S | L | I | S |
Query Conservation |   |
  |   |
|   |   |
|   |   |   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
| . |   |   |   |   |
|   |   |
|   |
|   |   |   |
|
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . |   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|
|   |
|   |
|
|   |   |
|   |   |   |   |
Template Sequence |   |
A | L | R | I | Y | L | K | D | N | L | T | Y | I | A | D | K | M | N | A | A | F | P | E | L | N | W | Q | . |
. |
. |
. |
. |
. |
. |
. |
. |
I | P | Q | S | T | Y | L | A | W | L | D | L | R | P | L | N | I | D | D | N | A | L | Q | K | A | L | I | E | Q | E | K | V | A | I | M | P | G | Y | T | Y | G | E | E | G |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| S | S |
|
|
|
| . | . | . | . | . | . | . | . | . |
|
| S | B |
| S |  |  |  |  |  |
| G | G | G |
|
|
|  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |
|  |  | G | G | G | G |
| G | G | G |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |
|  |  |  |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
. | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 |
  |
  |   |
336 | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | |
|
. | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
| . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
H | A | A | T | M | T | H | A | G | M | A | P | E | A | R | A | A | A | G | I | S | E | T | L | L | R | I | S | T | G | I | . |
. |
E | D | G | E | D | L | I | A | D | L | E | N | G | F | R | A | A | N |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|
|
|
|
|
|   | . | . |
|   |   |   |
|
|
|   |   |
|   |   |
|
|   |
|   |   |
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |
|
|
|
|   |   |   |   |   |   |   |
|   |   |
|
|   |   |
|   |   |
|
|   |   |   |
|
Template Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
R | G | F | V | R | L | N | A | G | C | P | R | S | K | L | E | K | G | V | A | G | L | I | N | A | I | R | A | V | R |
Template Known Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | T | T |  |  |  |  |  |
|
| S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Template Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
361 | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 |
  |