Job Description P00935 Confidence 99.96% Date Wed Jan 25 15:20:10 GMT 2012 Rank 47 Aligned Residues 332 % Identity 12% Template c3e9kA_ PDB info PDB header:hydrolase Chain: A: PDB Molecule:kynureninase; PDBTitle: crystal structure of homo sapiens kynureninase-3-hydroxyhippuric acid2 inhibitor complex Resolution 1.70 Å

Show / Hide SS confidence

Show / Hide Conservation and Alignment quality

		14	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.				.	.	.	.	.	60	.	.	.	.	.	.	.	.			.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.
Predicted Secondary structure																																											.	.	.															.	.
Query SS confidence																																											.	.	.															.	.
Query Sequence		L	N	D	D	E	Q	Y	G	C	V	V	P	P	I	H	L	S	S	T	Y	N	F	T	G	F	N	E	P	R	A	H	D	Y	S	R	R	G	N	P	T	R	.	.	.	D	V	V	Q	R	A	L	A	E	L	E	G	G	A	.	.	G	A	V	L	T	N	T	G	M	S	A	I	H	L	V	T	T	V	F	L
Query Conservation																																											.	.	.															.	.
Alig confidence																																											.	.	.															.	.
Template Conservation
Template Sequence		Y	F	L	G	N	S	L	G	L	Q	P	K	M	V	K	T	Y	L	E	E	E	L	D	K	W	A	K	I	A	A	Y	G	H	E	V	G	K	R	P	W	I	T	G	D	E	S	I	V	G	L	M	K	D	I	V	G	A	N	E	K	E	I	A	L	M	N	A	L	T	V	N	L	H	L	L	M	L	S	F	F
Template Known Secondary structure				B	T	T	T	S			B		T	T																G	G	G	G	G	T	S	S	S	S		G	G	G	T	T					G	G	G					T			G	G	G					S
Template Predicted Secondary structure
Template SS confidence
		70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.
		89	90				.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.						.	120	.	.	.	.	.						.	.	.	.	130	.	.	.	.				.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.
Predicted Secondary structure				.	.	.																													.	.	.	.	.								.	.	.	.	.										.	.	.
Query SS confidence				.	.	.																													.	.	.	.	.								.	.	.	.	.										.	.	.
Query Sequence		K	P	.	.	.	G	D	L	L	V	A	P	H	D	C	Y	G	G	S	Y	R	L	F	D	S	L	A	K	R	G	C	Y	R	.	.	.	.	.	V	L	F	V	D	Q	G	.	.	.	.	.	D	E	Q	A	L	R	A	A	L	.	.	.	A	E	K	P	K	L	V	L	V	E	S	P	S	N	P	L	L	R
Query Conservation				.	.	.																													.	.	.	.	.								.	.	.	.	.										.	.	.
Alig confidence				.	.	.																													.	.	.	.	.								.	.	.	.	.										.	.	.
Template Conservation
Template Sequence		K	P	T	P	K	R	Y	K	I	L	L	E	A	K	A	F	P	S	D	H	Y	A	I	E	S	Q	L	Q	L	H	G	L	N	I	E	E	S	M	R	M	I	K	P	R	E	G	E	E	T	L	R	I	E	D	I	L	E	V	I	E	K	E	G	D	S	I	A	V	I	L	F	S	G	V	H	F	Y	T	G	Q
Template Known Secondary structure					S	S	S							T	T																T	T														T	T		S	S														G	G	G								S	B		T	T	T		B
Template Predicted Secondary structure
Template SS confidence
		150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.
		153	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.		180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.
Predicted Secondary structure																													.																																																			.	.
Query SS confidence																													.																																																			.	.
Query Sequence		V	V	D	I	A	K	I	C	H	L	A	R	E	V	G	A	V	S	V	V	D	N	T	F	L	S	P	.	A	L	Q	N	P	L	A	L	G	A	D	L	V	L	H	S	C	T	K	Y	L	N	G	H	S	D	V	V	A	G	V	V	I	A	K	D	P	D	V	V	T	E	L	A	W	W	A	N	N	I	.	.
Query Conservation																													.																																																			.	.
Alig confidence																													.																																		.	.																.	.
Template Conservation																																																															.	.
Template Sequence		H	F	N	I	P	A	I	T	K	A	G	Q	A	K	G	C	Y	V	G	F	D	L	A	H	A	V	G	N	V	E	L	Y	L	H	D	W	G	V	D	F	A	C	W	C	S	Y	K	Y	L	N	A	G	A	G	G	I	A	G	A	F	I	.	.	H	E	K	H	A	H	T	I	K	P	A	L	V	G	W	F	G
Template Known Secondary structure		B													T	T								T	T	T	T	T	T	S								T								S	S	S	T	T				T	T								.	.		G	G	G	T	T	T	S			S	S			G	G	G
Template Predicted Secondary structure																																																															.	.
Template SS confidence
		230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290			.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.
																									230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.		.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.
Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																							.
Query SS confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																							.
Query Sequence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	G	V	T	G	G	A	F	D	S	Y	L	L	L	R	G	L	R	T	L	V	P	R	.	M	E	L	A	Q	R	N	A	Q	A	I	V	K	Y	L	Q	T	Q	P	L	V	K	K	L	Y	H	P	S	L	P	E	N	Q	G
Query Conservation		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																							.
Alig confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																							.																																		.
Template Conservation																																																																																	.
Template Sequence		H	E	L	S	T	R	F	K	M	D	N	K	L	Q	L	I	P	G	V	C	G	F	R	I	S	N	P	P	I	L	L	V	C	S	L	H	A	S	L	E	I	F	K	Q	A	T	M	K	A	L	R	K	K	S	V	L	L	T	G	Y	L	E	Y	L	I	K	H	N	Y	G	V	V	N	I	I	T	P	S	H	.
Template Known Secondary structure		B						T	T			S				B		S	S	G	G	G	G			S																																																			S		S	S	.
Template Predicted Secondary structure																																																																																	.
Template SS confidence
		308	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.
		286	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		H	E	I	A	A	R	Q	Q	K	G	F	G	A	M	L	S	F	E	L	D	G	D	E	Q	T	L	R	R	F	L	G	G	L	S	L	F	T	L	A	E	S	L	G	G	V	E	S	L	I	S	H	A	A	T	M	T	H	A	G	M	A	P	E	A	R	A	A	A	G	I	S	E	T	L	L	R	I	S	T	G
Query Conservation
Alig confidence		.	.	.	.	.	.	.																.	.	.																				.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation		.	.	.	.	.	.	.																.	.	.																				.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		.	.	.	.	.	.	.	V	E	E	R	G	C	Q	L	T	I	T	F	S	V	P	.	.	.	N	K	D	V	F	Q	E	L	E	K	R	G	V	V	C	D	K	R	N	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	P	N	G	I	R	V	A	P	V
Template Known Secondary structure		.	.	.	.	.	.	.	G	G	G	B		S									T	.	.	.	T									T	T	T							T	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	T	T					B
Template Predicted Secondary structure		.	.	.	.	.	.	.																.	.	.																				.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
									396	.	.	.	400	.	.	.	.	.	.	.	.	.	410				.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.																												430	.	.	.	.	.	.	.	.
			366	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.
Predicted Secondary structure		.
Query SS confidence		.
Query Sequence		.	I	E	D	G	E	D	L	I	A	D	L	E	N	G	F	R	A	A	N	K
Query Conservation		.
Alig confidence		.
Template Conservation
Template Sequence		P	L	Y	N	S	F	H	D	V	Y	K	F	T	N	L	L	T	S	I	L	D
Template Known Secondary structure		T	T	T																		T
Template Predicted Secondary structure
Template SS confidence
		439	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.

No model constructed - rank, confidence too low

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions