|   |
31 | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 |
Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Y | G | D | F | D | R | Y | V | L | A | L | S | W | Q | T | G | F | C | Q | S | Q | H | D | R | N | R | N | E | R | D | E | C | R | L | Q | T | E | T | T | N | K | A | D | F | L | T | V | H | G | L | W | P | G | L | P | K | S | V | A | A | R | G | V | D | E | R | R | W | M | R | F | G | C | A | T | R | P | I | P | N |
Query Conservation |   |
  |
|
|
|
|   |
|
|
|
|
|
|
|   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|
|
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
  |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|   |   |   |
|
|
|
|
|
|
|
|   |   |   |   |
|   |   |
|   |   |
|   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . |
Template Sequence |   |
N | S | P | G | G | S | L | L | Q | T | Q | F | W | D | Y | D | P | S | D | G | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
P | S | D | S | W | T | I | H | G | L | W | P | D | N | C | D | G | T | Y | Q | E | Y | C | D | E | S | R | E | Y | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
|
| S |
|
|  |  |  |  |  |  |  |
|
| B | T | T | B |
| S | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
| T | T |
|
|  |  |  |  |  |  |  |  |
| T | T | S |
| B |
|
|
|
|
| G | G | G |
|
| . | . | . | . | . | . | . | . | . | . | . |
Template Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
24 | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | |
|
|
|
|
|
|
|
|
|
|
  |
  |   |
111 | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | |
|
|
. | . | 150 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |
|
|
|
|
|  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  | . | . | . |  |  |  |  |  |  |  |  |
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | P | E | A | R | A | S | R | M | C | S | S | P | E | T | G | L | S | L | E | T | A | A | K | L | S | E | V | M | P | G | A | G | G | R | S | C | . |
. |
. |
L | E | R | Y | E | Y | A | K | H | G | A | C | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
F | G | F | D | P | D | A | Y | F | G | T | M | V | R | L |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |
|
|   |   |   |   |   |   |   | . | . | . |
|
|   |
|
|
|   |
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |
|
|   |   |
|
|   |
|
Alig confidence |   |
. | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|
|   |
|
|
|
|
|
|
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|
|   |
|
Template Sequence |   |
. |
. |
. |
. |
. |
. |
S | N | I | T | S | I | L | E | A | Q | N | R | T | E | L | L | S | Y | M | K | E | Y | W | P | D | Y | E | G | A | D | E | D | E | S | F | W | E | H | E | W | N | K | H | G | T | C | I | N | T | I | E | P | S | C | Y | T | D | Y | Y | A | Q | E | E | V | G | D | F | F | Q | Q | V | V | D | L |
Template Known Secondary structure |   |
. | . | . | . | . | . | S |
|  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |  |  |  |  |  | S |
|
| T | T |
| G | G | G |  |  |  |  |  |  |  |  |  |  |  | T | G | G | G |
| G | G | G | S | G | G | G | B | S | S |
|
| T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
. | . | . | . | . | . |
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
|
73 | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . |
  |
  |   |
175 | . | . | . | . | 180 | . | . | . | . | |
|
. | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . |
Predicted Secondary structure |   |
 |  |  |
|
|
|  |  |  |  | . | . |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
N | Q | E | I | K | E | S | E | A | G | . |
. |
K | F | L | A | D | N | Y | G | K | T | V | S | R | R | D | F | D | A | A | F | A | K | S | W | G | K | E | N | V | K | A | V | K | L | T | C | Q | G | N | P | A | Y | L | T | E | I | Q | I | S | I | K | A | D | A | I | N | A | P | L | S | A | N | S | F | L | P | Q | P |
Query Conservation |   |
  |   |   |   |
|   |   |   |   |   | . | . |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |
|
|   |   |
|   |
|   |   |   |   |   |   |
|   |
|   |
|   |   |
|   |   |   |
|   |
|
|   |
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |
|
|   |   |   |
|   |   |   |
|
|   |
|
|   |   |   |   |
|   |   |   |   |
|   |   |
|
|   |   |   |   |   | . | . | . |
|   |   |
|   |
|   |
|   |   |   | . | . |   |
|   |
|
|   |   |
|
|   |
|   | . | . | . |
|   |   |   |   |   |   |
|   |
|   |   |
Template Sequence |   |
F | K | T | L | D | S | Y | T | A | L | S | D | A | G | I | T | P | S | E | D | A | T | Y | K | L | S | D | I | E | D | A | L | A | A | I | H | D | . |
. |
. |
G | Y | P | P | Y | V | G | C | E | D | G | . |
. |
A | L | S | Q | L | Y | Y | Y | F | N | V | K | . |
. |
. |
G | S | A | I | G | G | T | Y | V | A | S | E |
Template Known Secondary structure |   |
 | T | T |
|
|  |  |  |  |  |  |  | T | T |
|
|
|
| S | S |
|
| B |
|  |  |  |  |  |  |  |  |  | T | T | T | T | . | . | . | T |
|
|
|  |  |  |  |  | T | T | . | . |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | S |
| T | T | T | S |  |  |  |  |
|
|
Template Predicted Secondary structure |   |
 |  |  |
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |
|  |  |  |  |  |  |  |  |  |  |  |
|
| . | . | . |
|
|
|  |  |  |  |  |  |
|
| . | . |  |  |  |  |  |  |  |  |  |  |
|
| . | . | . |
|
|
|
|
|
|
|  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
147 | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | |
|
|
. | . | . | . | . | . | 190 | . | . | . | . | |
|
. | . | . | . | . | 200 | . | . | . | . | . | . | |
|
|
. | . | . | 210 | . | . | . | . | . | . | . | . |
  |
  |   |
|
|
253 | . | . | . | . | . | . | 260 | |
. | . | . | . | . | . | . |
Predicted Secondary structure |   |
. | . |
|
|
|
|
|
|
|  | . |  |  |  |
|
|
|
|
Query SS confidence |   |
. |
. |
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
H | P | G | N | C | G | K | T | . |
F | V | I | D | K | A | G |
Query Conservation |   |
. | . |   |   |   |   |
|
|   |   | . |   |   |
|
|   |   |
|
Alig confidence |   |
. | . |
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |
|
|   |   |   |
|   |
|   |
|
|   |
Template Sequence |   |
R | L | E | D | S | N | C | K | D | S | G | I | K | Y | P | P | K | Y |
Template Known Secondary structure |   |
| S | S |
| B | S | S |
| S | S |
| B | B |
|
|
| T | T |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
219 | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . |
  |