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Job DescriptionP39452
Confidence100.00%DateThu Jan 5 12:00:51 GMT 2012
Rank4Aligned Residues625
% Identity28%Templatec3hnfA_
PDB info PDB header:oxidoreductaseChain: A: PDB Molecule:ribonucleoside-diphosphate reductase large subunit; PDBTitle: crystal structure of human ribonucleotide reductase 1 bound to the2 effectors ttp and datp
Resolution3.16 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   1........10.........20.........30.........40.........50.........60......... 70.....
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Query Sequence  MATTTAECLTQETMDYHALNAMLNLYDSAGRIQFDKDRQAVDAFIATHVRPNSVTFSSQQQRLNWLVNE. . . . . GYYDES
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Template Sequence  LAAETAATLTTKHPDYAILAARIAVSNLHKETKKVFS. . . . . . . . . . . . . . . . . . . DVMEDLYNYINPHNGKHSPMVAKS
Template Known Secondary structure  GGGT
TTTS
S
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B
TTT

B

SS
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   5960.........70.........80.........90..... ....100.........110.........
 
   76...80.........90.........100.........110.........120.........130.........140.........150.....
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Query Sequence  VLNRYSRDFVITLFTHAHTSGFRFQTFLGAWKFYTSYTLKTFDGKRYLEDFADRVTMVALTLAQGDETLALQLTDEMLSG
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Template Sequence  TLD. IVLANKDRLNSAIIYDRDFSYNYFGFKTLERSYLLKI. NGKVA. ERPQHMLMRVSVGIHKEDIDAAIETYNLLSER
Template Known Secondary structure  .TTTT

GGGGGSS
TS
BS.SSSB
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TT
TT
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   120.. .......130.........140.........150......... 160.... .....170.........180.........190......
 
   156...160.........170.........180... ......190.........200.........210.........220.........230....
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Query Sequence  RFQPATPTFLNCGKQQRGELVSCFLLRI. EDNMESIGRAVNSALQLSKRGGGVAFLLSNLREAGAPIKRIENQSSGVIPV
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Template Sequence  WFTHASPTLFNAGT. NRPQLSSCFLLSMKDDSIEGIYDTLKQCALISKSAGGIGVAVSCIRATGSYIAGTNGNSNGLVPM
Template Known Secondary structure  S
TTS.SS








SST



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TTTT


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   197..200.........210 .........220.........230.........240.........250.........260.........270.....
 
   235....240.........250.........260.........270.........280.........290.........300.........310....
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Query Sequence  MKMLEDAFSYANQLGARQGAGAVYLHAHHPDILRFLDTKRENADEKIRIKTLSLGVVIPDITFHLAKENAQMALFSPYDV
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Template Sequence  LRVYNNTARYVDQP. . . . GAFAIYLEPWHLDIFEFLDLKK. . . . . . . . . RDLFFALWIPDLFMKRVETNQDWSLMCPNEC
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TTBTTTTS

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TTTS
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   276...280......... 290.........300.........310. ........320.........330.........340..
 
   315....320.........330.........340.........350.........360.........370......... 380.........390..
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Query Sequence  ERVYGKPFADVAISQHYDELVADERIRKKYLNARDFFQRLAEIQFESGYPYIMYEDTVNRANPIA. . GRINMSNLCSEIL
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Template Sequence  PGL. . DEVWGEEFEKLYASYEKQGRVRK. VVKAQQLWYAIIESQTETGTPYMLYKDSCNRKSNQQNLGTIKCSNLCTEIV
Template Known Secondary structure  TTT..TS

TT


S.S
ST
TTGGG






TTS


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   357.. 360.........370.........380.. .......390.........400.........410.........420.........430...
 
   393......400.........410.........420...... ...430.........440.........450.........460......
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Query Sequence  QVNSASEYDENLDYTRTGHDISCNLGSLNIAHTM. . . . . . DSPDFARTVETAVRGLTAVSDMSHIRSVPSIEAGNAASHA
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Template Sequence  EYTSKDE. . . . . . . . . . . . VAVCNLASLALNMYVTSEHTYDFKKLAEVTKVVVRNLNKIIDINYY. PVPEACLSNKRHRP
Template Known Secondary structure 



SS
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B

GGGSB
TTS
B



.SS

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   434.....440 .........450.........460.........470.........480...... ...490.........500
 
   467..470.........480.........490.........500.........510.........520.........530.........540......
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Query Sequence  IGLGQMNLHGYLAREGIAYGSPEALDFTNLYFYAITWHALRTSMLLARERGETFAGFKQSRYASGEYFSQYLQGNWQPKT
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Template Sequence  IGIGVQGLADAFILMRYPFESAEAQLLNKQIFETIYYGALEASCDLAKEQG. PYETYEGSPVSKGIL. . . . . . . . . . . . .
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T

TTS
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TT
TTSTTTTT

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   501........510.........520.........530.........540.........550. ........560......
 
   547..550.........560.........570.........580.........590.........600.........610.........
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Query Sequence  AKVGELFTRSGITLPTREMWAQLRDDVMRYGIYNQNLQAVPPTGSISYINHATSSIHPIVAKVEIRKEGKTGR. . . . . . .
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Template Sequence  . . . . . QYDMWNVTPTDLWDWKVLKEKIAKYGIRNSLLIAPMPTASTAQILGNNESIEPYTSNIYTRRVLSGEFQIVNPHL
Template Known Secondary structure  .....TT



TTS


S
S

B




TT


TT


S
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B
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   567..570.........580.........590.........600.........610.........620.........630.........640.
 
   620.........630.........640.........650.........660.........670......
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . VYYPAPFMTNENLALYQDAYEIGAEKIIDTYAEATRHVDQGLSLTLFFPDTATTRDI
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Template Sequence  LKDLTERGLWHEEMKNQIIACNGSIQSIPEIPDDLKQLYKTVWEISQKTVLKMAAERGAFIDQSQSLNIHIAEP. NYGKL
Template Known Secondary structure  TT


TTT

TT
TTS
T

GGGS
TTS
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SS
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   642.......650.........660.........670.........680.........690.........700.........710..... ....720
 
   677..680.........690 .......
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Query Sequence  NKAQIYAWRKGIKT. LYYIRLR
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Template Sequence  TSMHFYGWKQGLKTGMYYLRTR
Template Known Secondary structure  T
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   721........730.........740..
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
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