|   |
18 | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
I | H | A | G | E | V | G | M | Y | V | C | G | I | T | V | Y | D | L | C | H | I | G | H | G | R | T | F | V | A | F | D | V | V | A | R | Y | L | R | F | L | G | Y | K | L | K | Y | V | R | N | I | T | D | I | D | D | K | I | I | K | R | A | N | E | N | G | E | S | F | V | A | M | V | D | R | M | I | A | E | M | H |
Query Conservation |   |
  |   |   |   |   |
|   |   |
|   |
|
|
|
|   |   |
|   |   |
|
|
|
|
|
|   |   |
|   |   |
|
|
|
|
|   |
|
|   |   |
|   |   |
|   |   |
|   |   |
|   |
|   |
|   |
|
|   |   |   |
|   |   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |
|
|
|
|
|
|
| . | . |
|
|
|
|
|   |
|
|
|
|
|
|
|
|
|
|   |
|   |   |   |
|
|   | . | . | . | . | . |   |   |
|   |   |
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . |
|   |
|   |   |   |
|   |   |   |   |
|   |
Template Sequence |   |
K | Y | P | R | V | V | T | R | F | P | . |
. |
P | D | P | S | G | Y | A | H | L | G | H | V | F | A | S | L | L | D | F | N | T | A | R | Q | . |
. |
. |
. |
. |
Y | G | G | Q | F | N | L | R | M | D | D | T | N | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
P | E | L | A | R | Q | E | Y | V | D | S | I | A |
Template Known Secondary structure |   |
S |
| S | S |
|  |  |  |  |
| . | . |
|
| S | S | S |
|
| B |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | T | T |
|  |  |  |  |  |  |
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | T | T | T |
|
|  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |
|
| . | . |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . |  |
|
|  |  |  |  |  |  |  |
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
64 | . | . | . | . | . | 70 | . | . | . | |
|
. | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | |
|
|
|
|
. | . | 100 | . | . | . | . | . | . | . | . | . | 110 | |
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 120 | . | . | . |
  |
  |   |
98 | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
150 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |
| . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
Query Sequence |   |
K | D | F | D | A | L | N | I | L | R | P | D | M | E | P | R | A | T | H | H | I | A | E | I | I | E | L | T | E | Q | L | I | A | K | G | H | A | Y | V | A | D | N | G | D | V | M | F | D | V | P | T | D | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
P | T | Y | G | V | L | S | R | Q | D | . |
. |
. |
. |
. |
Query Conservation |   |
  |   |   |   |   |
|   |
|   |   |   |
|   |   |   |
|   |
|
|   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |   |   |   |   |   |   |
|
|   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |
|   |
|   |   |   |   | . | . | . | . | . |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
Template Conservation |   |
|
|
|   |
|
|
|
|   |
|
|
|   |
|   |   |
|
|
|
|   |   |   |
|   |   |   |
|   |   |
|
|   |   |
|   |
|
|   |
| . | . | . | . | . |   |
|
|   |
|
|
|   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |
|   |   |
|   |
|
|
|
|   |   |   |
Template Sequence |   |
D | D | L | K | W | L | G | L | D | W | G | E | H | F | Y | Y | A | S | D | Y | F | D | R | Y | Y | A | Y | A | E | Q | L | I | R | Q | G | D | A | Y | V | E | . |
. |
. |
. |
. |
S | V | S | P | E | E | L | S | R | L | R | G | N | A | T | T | P | G | T | P | S | P | Y | R | D | R | S | V | E | E | N | L | D | L | L |
Template Known Secondary structure |   |
 |  |  |  |  |  | T |
|
|
| T | T |
|  |  |  | G | G | G | G |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | S |  |  |  |  | . | . | . | . | . |
| S |
|  |  |  |  |  |  |  |  |
| B | T | T | B |
|
|
|
|
| T | T | T | T |
|
|  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
| . | . | . | . | . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
124 | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | |
|
|
|
|
. | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . |
  |
  |   |
|
|
|
|
|
|
|
|
|
160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 |
Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
Query SS confidence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
L | D | Q | L | Q | A | G | A | R | V | D | V | V | D | D | K | R | N | P | M | D | F | V | L | W | K | M | S | K | E | G | E | P | S | W | P | S | P | W | G | A | G | R | P | G | W | H | I | E | C | S | A | M | N | C | K | Q | L | G | N | H | F | D | I | H | G | G | G | S | D | L |
Query Conservation |   |
. | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |
|   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |
|   |
|   |
Alig confidence |   |
. | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |   |
|   |   |   |   |   |   |   |   |
|
|   |
|   |
|   |   |   |   |
|   |   |   |
|
|   |
|   |   |
|
|   |   |   |   |
|   |   |   |
|   |
|   | . |   |   |   |
|
|
|   |
|
|   |   |
| . | . | . |
|
|   |
|   |
|
|
|
|
|
|
|
|   |
|   |
Template Sequence |   |
R | R | M | K | A | G | E | F | A | D | G | E | H | V | L | R | A | K | I | D | L | T | A | P | N | M | K | L | R | D | P | V | L | Y | R | I | V | N | K | P | H | F | R | T | S | D | E | W | . |
H | I | Y | P | A | Y | D | F | E | H | P | L | . |
. |
. |
Q | D | A | I | E | G | V | T | H | S | M | C | S | L | E | F |
Template Known Secondary structure |   |
 |  |  |  | T | T |
| S |
| T | T | S |
|  |  |  |  |
|
|
| T | T |
| S | S | G | G | G | S | S |
|  |  |  |  |  |
|
|
|
| B | T | T | T | B | T | S |
| . | S |  |  |  |
|  |  |  |  |  |  |  | . | . | . |  |  |  |  |  | T |
| S |  |  |  |  |  | G | G | G |
Template Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|  |  |  |  |  |
|  |  |  |  | . | . | . |
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
199 | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | |
. | . | . | 250 | . | . | . | . | . | . | . | . | |
|
|
. | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . |
  |
  |   |
231 | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | 280 | . | . | |
. | . | . | . | . | . | . | 290 | . | . | . | . |
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|  |  |  |  |  |  | . |  |
|
|  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
M | F | P | H | H | E | N | E | I | A | Q | S | T | C | A | H | D | G | Q | Y | V | N | Y | W | M | H | S | G | M | V | M | V | D | R | E | K | M | S | K | S | L | G | N | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
F | F | T | V | R | D | V | L | K | . |
Y | Y | D | A | E | T | V | R | Y | F | L | M |
Query Conservation |   |
  |   |   |
|   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |
|
|
|
|
|   |
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |
|   |   |   |
|
|
|   | . |   |   |   |   |
|   |   |
|
|   |
|
|
Alig confidence |   |
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   | . |   |
|   |   |
|   |   |
|   |   |
|
|
|   |   |   |   |
| . |   |   |   |   |   |   |
|
|
|   |   |   |   |   |
|
|
|
|
|
|   |   |   |
|   |   |   |   |
|   |
|
|
|
|
|
|   |   |
|
|   |   |
|
|
|
|
|   |   |
|
|
|
|   |   |
|   |   |
Template Sequence |   |
V | D | . |
N | R | A | I | Y | D | W | L | M | E | K | L | N | F | D | P | R | P | . |
H | Q | Y | E | F | G | R | R | G | L | E | Y | T | I | T | S | K | R | K | L | R | E | L | V | Q | A | G | R | V | S | G | W | D | D | P | R | M | P | T | L | R | A | Q | R | R | L | G | V | T | P | E | A | V | R | A | F | A | A |
Template Known Secondary structure |   |
T | T | . | T |  |  |  |  |  |  |  |  |  |  | T | T |
| S | S |
|
| . |  |  |  |  |  |
|
|  |  |  | T | T |
|
|
|
|  |  |  |  |  |  |  |  |  | T | T | S | S | S | S | T | T |
| T | T | S | S | B |  |  |  |  |  |  |  | T |
|
|  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
| . |
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
| . |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
275 | . | |
. | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | |
. | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . |
  |
  |   |
295 | . | . | . | . | |
300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
| . |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
S | G | H | Y | R | . |
S | Q | L | N | Y | S | E | E | N | L | K | Q | A | R | A | A | L |
Query Conservation |   |
  |   |   |   |   | . |   |   |   |   |
|
|   |
|   |
|   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
|   |   |
Template Sequence |   |
Q | I | G | V | S | R | T | N | R | T | V | D | I | A | V | Y | E | N | A | V | R | D | D |
Template Known Secondary structure |   |
 | S |
|
|
| S | S |
|  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
353 | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . |
  |