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Job DescriptionP21888
Confidence100.00%DateThu Jan 5 11:38:38 GMT 2012
Rank19Aligned Residues423
% Identity19%Templatec1wz2B_
PDB info PDB header:ligase/rnaChain: B: PDB Molecule:leucyl-trna synthetase; PDBTitle: the crystal structure of leucyl-trna synthetase and trna(leucine)2 complex
Resolution3.21 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   25....30.........40.........50.........60.........70........ .80
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Query Sequence  MYVCGITVYDLCHIGHGRTFVAFDVVARYLRFLGYKLKYVRNITDIDDKIIKRA. . . . . . . . . . . . . . . . . . . . . . . . NE
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Template Sequence  ITVAFPYLSGHLHVGHARTYTIPDVIARFKRMQGYNVLFPMAWHITGSPIVGIAERIKNRDPKTIWIYRDVYKVPEEILW
Template Known Secondary structure 


B
SS

BTT


B



BB

SSTT
TTS


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   38.40.........50.........60.........70.........80.........90.........100.........110.......
 
   81........90.........100.........110..... ....120.........130.........140........
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Query Sequence  NGESFVAMVDRMIAEMHKDFDALNILRPDMEPRAT. . . . . HHIAEIIELTEQLIAKGHAYVADNGDVMFDVPT. . . . . . .
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Template Sequence  TFEDPINIVKYFMKAAKETFIRAGFSVDWSREFYTTSLFPPFSKFIEWQFWKLKEKGYIVKGAHRVRWDPVVGTPLGDHD
Template Known Secondary structure  GGGSTTT



TTS

B
STTSTTTTT






TTTS
B

SSS
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   118.120.........130.........140.........150.........160.........170.........180.........190.......
 
  
Predicted Secondary structure  ................................................................................
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Query Conservation  ................................................................................
Template Conservation 
              

 
        
 
 



 

    
  
 
   
           
  
             
Template Sequence  LMEGEDVPILDYIIIKFELRENGEVIYLPAATLRPETVYGVTNMWVNPNATYVKAKVRRKDKEETWIVSKEAAYKLSFQD
Template Known Secondary structure 
SS









SSS

S
GGGGGG


SSS

SS
SS
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   198.200.........210.........220.........230.........240.........250.........260.........270.......
 
   149150.........160.........170.........180......
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . DPTYGVLSRQDLDQLQAGARVDVVDDKRNPMDFVLWKM. . . . . . . . . . . . . . . . . . .
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Template Conservation            
  
 
     
       

    
    


 
   


   
                        
Template Sequence  REIEVIEEFKGEKLIGKYVRNPVSGDEVIILPAEFVDPDNATGVVMSVPAHAPFDHVALEDLKRETEILEKYDIDPRIVF
Template Known Secondary structure 


SSTTSS

SSSS

SS

SSSTTS

TTS
TTTTTTTS

S

S



TT







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   278.280.........290.........300.........310.........320.........330.........340.........350.......
 
  
Predicted Secondary structure  ................................................................................
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Query Conservation  ................................................................................
Template Conservation           
         
                       
  
  
   
   
   
                
 
Template Sequence  PAVEEVNKLGIKSQKDKEKLEQATKTIYKAEYHKGIFKVPPYEGKPVQEVKEAIAKEMLEKGIAEIMYEFAEKNVISRFG
Template Known Secondary structure 
SS

TTTSSS


SS
TTTTS
B

SSSS
SSBTTTTTS


SSS

B
SSS
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   374.....380.........390.........400.........410.........420.........430.........440.........450...
 
   187..190.........200...
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . SKEGEPSWPSPWGAGRP. . . . . . . . . . . . . .
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Template Sequence  NRAVIKIIHDQWFIDYGNPEWKEKARKALERMKILPETRRAQFEAIIDWLDKKACARKIGLGTPLPWDPEWVIESLSDST
Template Known Secondary structure  SB



SS
S

TTTTS
SSTTS




BSSSSS
TT
TTS
TT
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   454.....460.........470.........480.........490.........500.........510.........520.........530...
 
   204.....210......... 220.........230
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Query Sequence  . . GWHIECSAMNCKQLGN. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . HFDIHGGGSDL
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Template Conservation 
                              
                  
             
    
 
    
 
 
Template Sequence  IYMAYYTISRHINKLRQEGKLDPEKLTPEFFDYIFLEEFSEDKEKELEKKTGIPAEIIHEMKEEFEYWYPLDWRCSGKDL
Template Known Secondary structure  STTT


GGG

TTTS


T


S
SGGG
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   534.....540.........550.........560.........570.........580.........590.........600.........610...
 
   231........240....... ..250.........260.........270.........280.........290..... ....300........
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Query Sequence  MFPHHENEIAQSTCAHD. GQYVNYWMHSGMVMVDREKMSKSLGNFFTVRDVLKYYDAETVRYFLMS. GHYRSQLNYSEEN
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Template Sequence  IPNHLTFFIFNHVAIFREEHWPKGIAVNGFGTLEGQKMSKSKGNVLNFIDAIEENGADVVRLYIMSLAEHDSDFDWRRKE
Template Known Secondary structure  TTTS
STTS




SSS


TTT



BTT


TT


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   614.....620.........630.........640.........650.........660.........670.........680.........690...
 
   309310.........320.........330...... ...340.........350.........360. ........370..
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Query Sequence  LKQARAALERLYTALRGTDKTVAPAGGE. . . . . . . . . . . . . AFEARFIEAMDDDFNTPEAYSVLFD. MAREVNRLKAE. .
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Template Conservation                                  
  

  
      
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Template Sequence  VGKLRKQIERFYELISQFAEYEVKGNVELKDIDRWMLHRLNKAIKETTNAL. EEFRTRTAVQWAFYSIMNDLRWYLRRTE
Template Known Secondary structure  SS








.TT
TTT
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   694.....700.........710.........720.........730.........740.... .....750.........760.........770..
 
   373......380.........390.........400.........410. ........420.........430.........440....
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Query Sequence  . . . DMAAANAMASHLRKLSAVLGLLEQEPEAFLQSGAQADDS. . . . . EVAEIEALIQQRLDARKAKDWAAADAARDRLNE
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Template Conservation            
   
  
  

 
  
  




  

   

     
                 
      

     
Template Sequence  GRDDEAKRYVLRTLADVWVRLMAPFTPHICEELWEKLGGEGFVSLAKWPEPVEEWWNETIEAEEEFIRSVMEDIKEIIEV
Template Known Secondary structure  T


TTTSSS

S
GGGS





SS


T
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   773......780.........790.........800.........810.........820.........830.........840.........850..
 
   445...
Predicted Secondary structure 


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Query Sequence  MGIV
Query Conservation   

 
Alig confidence 



Template Conservation      
Template Sequence  AKIE
Template Known Secondary structure  S


Template Predicted Secondary structure 


Template SS confidence 



   853...
 
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Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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