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Job DescriptionP21888
Confidence100.00%DateThu Jan 5 11:38:38 GMT 2012
Rank24Aligned Residues385
% Identity22%Templatec1wkbA_
PDB info PDB header:ligaseChain: A: PDB Molecule:leucyl-trna synthetase; PDBTitle: crystal structure of leucyl-trna synthetase from the2 archaeon pyrococcus horikoshii reveals a novel editing3 domain orientation
Resolution2.05 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   13......20....... ..30.........40.........50.........60.........70........
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Query Sequence  EEFKPIHAGEVGMYV. . CGITVYDLCHIGHGRTFVAFDVVARYLRFLGYKLKYVRNITDIDDKIIKRA. . . . . . . . . . . .
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Template Sequence  EPNIRDKPKEKKFYITVAFPYLSGHLHVGHARTYTIPDVIARFKRMQGYNVLFPMAWHITGSPIVGIAERIKNRDPKTIW
Template Known Secondary structure 


GGGS
GGG


BTTS

BT




BB

BSTT
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   24.....30.........40.........50.........60.........70.........80.........90.........100...
 
   7980.........90.........100.........110..... ....120.........130.........140.
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Query Sequence  . . . . . . . . . . . . NENGESFVAMVDRMIAEMHKDFDALNILRPDMEPRAT. . . . . HHIAEIIELTEQLIAKGHAYVADNGD
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Template Conservation                                
     

   

     
    
         
  
   



     
Template Sequence  IYRDVYKVPEEILWTFEDPINIVKYFMKAAKETFIRAGFSVDWSREFYTTSLFPPFSKFIEWQFWKLKEKGYIVKGAHRV
Template Known Secondary structure  TS


GGGSTT



GGG

B
STTSTT
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   104.....110.........120.........130.........140.........150.........160.........170.........180...
 
   142.......150.........160.
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Query Sequence  VMFDVPTDPTYGVLSRQDLD. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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Template Sequence  RWDPVVGTP. . . . LGDHDLMEGEDVPILDYIIIKFELRENGEVIYLPAATLRPETVYGVTNMWVNPNATYVKAKVRRKDK
Template Known Secondary structure  TTTT....

TT

SB
SS



SS
S

S
GGGGGG


TTS
TT
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   184.....190.. .......200.........210.........220.........230.........240.........250.........
 
   162.......170.........180......
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . QLQAGARVDVVDDKRNPMDFVLWKM.
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Template Conservation                              
  
 
     
       
     
    


 
   


   
       
Template Sequence  EETWIVSKEAAYKLSFQDREIEVIEEFKGEKLIGKYVRNPVSGDEVIILPAEFVDPDNATGVVMSVPAHAPFDHVALEDL
Template Known Secondary structure  TTSS

TTTTTTT

SSS


TTS
TTSTTS

TTT



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   260.........270.........280.........290.........300.........310.........320.........330.........
 
  
Predicted Secondary structure  ................................................................................
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Query Conservation  ................................................................................
Template Conservation                             
                                 
         
   
   
Template Sequence  KRETEILEKYDIDPRIVFPAVEEVNKLGIKSQKDKEKLEQATKTIYKAEYHKGIFKVPPYEGKPVQEVKEAIAKEMLEKG
Template Known Secondary structure  S

S


TT
S







TT

SGGGTS


TT
S
TS

SGGGTTTTT
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   340.........350.........360.........370.........380.........390.........400.........410.........
 
   187..190.........
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . SKEGEPSWPSPWG
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Template Conservation                        
     



                     
             
 

 



  

Template Sequence  IAEIMYEFAEKNVISRFGNRAVIKIIHDQWFIDYGNPEWKEKARKALERMKILPETRRAQFEAIIDWLDKKACARKIGLG
Template Known Secondary structure  SSSS

B
TTS
B

TT
TSSGGG



SSSBS
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   436...440.........450.........460.........470.........480.........490.........500.........510.....
 
   200... ......210..
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Query Sequence  AGRP. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . GWHIECSAM
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Template Sequence  TPLPWDPEWVIESLSDSTIYMAYYTISRHINKLRQEGKLDPEKLTPEFFDYIFLEEFSEDKEKELEKKTGIPAEIIHEMK
Template Known Secondary structure 
TT
TTTSSSSTT


GGG

S


S

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   516...520.........530.........540.........550.........560.........570.........580.........590.....
 
   213......220.........230.........240....... ..250.........260.........270.........280.........290.
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Query Sequence  NCKQLGNHFDIHGGGSDLMFPHHENEIAQSTCAHD. GQYVNYWMHSGMVMVDREKMSKSLGNFFTVRDVLKYYDAETVRY
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Template Sequence  EEFEYWYPLDWRCSGKDLIPNHLTFFIFNHVAIFREEHWPKGIAVNGFGTLEGQKMSKSKGNVLNFIDAIEENGADVVRL
Template Known Secondary structure 
S
SGGGTTTS
GGGS



TTB


TTTT


B
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   596...600.........610.........620.........630.........640.........650.........660.........670.....
 
   292... ....300.........310.........320.........330...... ...340.........350.......
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Query Sequence  FLMS. GHYRSQLNYSEENLKQARAALERLYTALRGTDKTVAPAGGE. . . . . . . . . . . . . AFEARFIEAMDDDFNTPEAYS
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Template Conservation   
        
  
           
    
               
   
  

  
      
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Template Sequence  YIMSLAEHDSDFDWRRKEVGKLRKQIERFYELISQFAEYEVKGNVELKDIDRWMLHRLNKAIKETTNAL. EEFRTRTAVQ
Template Known Secondary structure 

TT


T



S




.TT
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   676...680.........690.........700.........710.........720.........730.........740.... .....750....
 
   358.360. ........370.. .......380.........390.........400..
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Query Sequence  VLFD. MAREVNRLKAE. . . . . DMAAANAMASHLRKLSAVLGLLEQEPEAFL
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Template Sequence  WAFYSIMNDLRWYLRRTEGRDDEAKRYVLRTLADVWVRLMAPFTPHICEEL
Template Known Secondary structure  TTTT


TTTS
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   755....760.........770.........780.........790.........800.....
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
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