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Job DescriptionP21888
Confidence100.00%DateThu Jan 5 11:38:38 GMT 2012
Rank26Aligned Residues394
% Identity23%Templatec1obhA_
PDB info PDB header:synthetaseChain: A: PDB Molecule:leucyl-trna synthetase; PDBTitle: leucyl-trna synthetase from thermus thermophilus complexed2 with a pre-transfer editing substrate analogue in both3 synthetic active site and editing site
Resolution2.2 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   1920.........30.........40.........50.........60.........70.........80.........90........
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Query Sequence  HAGEVGMYVCGITVYDLCHIGHGRTFVAFDVVARYLRFLGYKLKYVRNITDIDDKIIKRANENGESFVAMVDRMIAEMHK
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Template Sequence  GGGKQYVLVMFPYPSGDLHMGHLKNYTMGDVLARFRRMQGYEVLHPMGWDAFGLPAENAALKFGVHPKDWTYANIRQAKE
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SS
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   30.........40.........50.........60.........70.........80.........90.........100.........
 
   99100........ .110...... ...120.........130.........140.........150....
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Query Sequence  DFDALNILRP. DMEPRATH. . HIAEIIELTEQLIAKGHAYVADNGDVMFDVPTDPTYGV. . . . . . . . . . . . . . . . . . . . .
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Template Sequence  SLRLMGILYDWDREVTTCEPEYYRWNQWIFLKMWEKGLAYRAKEQWYLRITAYAERLLKDLEGLNWPEKVKAMQRAWIGR
Template Known Secondary structure  TT



GGG

BTTSTT



GGGGTTTT

S

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   111........120.........130.........140.........150.........160.........170.........180.........190
 
  
Predicted Secondary structure  ................................................................................
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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Template Sequence  SEGAEILFPVEGKEVRIPVFTTRPDTLFGATFLVLAPEHPLTLELAAPEKREEVLAYVEAAKRKTEIERQAEGREKTGVF
Template Known Secondary structure  BTT
S
S
GGGGGG


TT
TTTTTS

GGGTS
S
TTS


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   227..230.........240.........250.........260.........270.........280.........290.........300......
 
   155....160.........170.........180.....
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Query Sequence  . . . . . . . . . . . . . . . LSRQDLDQLQAGARVDVVDDKRNPMDFVLWK. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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Template Sequence  LGAYALNPATGERIPIWTADYVLFGYGTGAIMAVPAHDQRDYEFARKFGLPIKKVIERPGEPLPEPLERAYEEPGIMVNS
Template Known Secondary structure 
TTT

TTS
SSSTTS
GGG
T





BTTB


SS
SS


S


SS
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   307..310.........320.........330.........340.........350.........360.........370.........380......
 
   186...190.........200...
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . MSKEGEPSWPSPWGAGRP. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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Template Sequence  GPFDGTESEEGKRKVIAWLEEKGLGKGRVTYRLRDWLISRQRYWGTPIPMVHCVVPVPEEELPVLLPDLKDVEDISPLEA
Template Known Secondary structure  GGGTT
BTSS





SSS






GGG







S
STT

GGGG
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   387..390.........400.........410.........420.........430.........440.........450.........460......
 
   204.....210........ .220.........230....... ..240....
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Query Sequence  . . . . . . . . . . . . . . . . . . GWHIECSAMNCKQLG. . . . . . . . . . . . . . . NHFDIHGGGSDLMFPHHEN. . . . . . EIAQSTC
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Template Conservation                



 



                          
 
  
 
 
               
     
Template Sequence  HPEFYETTCPKRDTDTMDTFFDSSWYYLRYTDPHNDRLPFDPEKANAWMPVDQYIGGVEHAVLHLLYSRFFTKFLHDLGM
Template Known Secondary structure 






B



TTTTSTT
SSSS


SBS

TT
TTS
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   476...480.........490.........500.........510.........520.........530.........540.........550.....
 
   245....250.........260.. .......270
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Query Sequence  AHDGQYVNYWMHSGMVMV. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . DREKMSKS
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Template Sequence  VKVEEPFQGLFTQGMVLAWTDFGPVEVEGSVVRLPEPTRIRLEIPESALSLEDVRKMGAELRPHEDGTLHLWKPAVMSKS
Template Known Secondary structure 
S
S
SBS



TT

T
S
STT

TTSS

TT
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   562.......570.........580.........590.........600.........610.........620.........630.........640.
 
   271........280.........290..... ....300.........310.........320.........330..
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Query Sequence  LGNFFTVRDVLKYYDAETVRYFLMS. GHYRSQLNYSEENLKQARAALERLYTALRGTDKTVAP. . . . . . . . . . . . . . . . .
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Template Sequence  KGNGVMVGPFVKEQGADIARITILFAAPPENEMVWTEEGVQGAWRFLNRIYRRVAEDREALLETSGVFQAEALEGKDREL
Template Known Secondary structure  TT


BS
S
TTS

TT





GGG

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   642.......650.........660.........670.........680.........690.........700.........710.........720.
 
   333......340.........350.........360.........370.........380.........390.........400.........410.
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Query Sequence  . AGGEAFEARFIEAMDDDFNTPEAYSVLFDMAREVNRLKAEDMAAANAMASHLRKLSAVLGLLEQEPEAFLQSGAQADDS
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Template Sequence  YGKLHETLKKVTEDL. EALRFNTAIAALMEFLNALYEYRKDRPV. TPVYRTAIRYYLQMLFPFAPHLAEELWHWFWPDSL
Template Known Secondary structure  .TT
S
S.
TTTSTTT
SS
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   722.......730...... ...740.........750.........760.... .....770.........780.........790.........
 
   412..
Predicted Secondary structure 
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Query Sequence  EVA
Query Conservation     
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Template Conservation     
Template Sequence  FEA
Template Known Secondary structure 
Template Predicted Secondary structure 
Template SS confidence 


   800..
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
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