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Job DescriptionP21888
Confidence100.00%DateThu Jan 5 11:38:38 GMT 2012
Rank16Aligned Residues411
% Identity21%Templatec1ileA_
PDB info PDB header:aminoacyl-trna synthetaseChain: A: PDB Molecule:isoleucyl-trna synthetase; PDBTitle: isoleucyl-trna synthetase
Resolution2.50 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   1920......... 30.........40.........50.........60.........70.........80.
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Query Sequence  HAGEVGMYVCG. . ITVYDLCHIGHGRTFVAFDVVARYLRFLGYKLKYVRNITDIDDKIIKRANEN. . . . . . . . . . . . . . .
Query Conservation      
  
 

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Template Conservation       

 
   


 

 




       

 


 

 
  

   
 
  




  
 
                
Template Sequence  RKGGPRYTVYEGPPTANGLPHVGHAQARSYKDLFPRYKTMRGYYAPRRAGWDTHGLPVELEVEKKLGLKSKREIEAYGIE
Template Known Secondary structure  TTTS
B

B





TTS


TTTT
B





TT

S
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   34.....40.........50.........60.........70.........80.........90.........100.........110...
 
   82.......90.........100........ .110...... ...120.........130.........140........
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Query Sequence  . . GESFVAMVDRMIAEMHKDFDALNILRP. DMEPRATH. . HIAEIIELTEQLIAKGHAYVADNGDVMFDVPT. . . . . . . .
Query Conservation  ..
    
               
 
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Template Conservation                          
   

     
 

         
  
   



     
 


   
 

  

Template Sequence  RFNQACRESVFTYEKEWEAFTERIAYWVDLEDAYATLEPTYIESIWWSLKNLFDRGLLYRDHKVVPYCPRCGTPLSSHEV
Template Known Secondary structure  TTTTTTTT


TTSTT


TTTT

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   114.....120.........130.........140.........150.........160.........170.........180.........190...
 
  
Predicted Secondary structure  ................................................................................
Query SS confidence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Query Conservation  ................................................................................
Template Conservation                 
 
            
   

 
 

 
     
 
   
                         
Template Sequence  ALGYKEIQDPSVYVRFPLKEPKKLGLEKASLLIWTTTPWTLPGNVAAAVHPEYTYAAFQVGDEALILEEGLGRKLLGEGT
Template Known Secondary structure  TBSSGGGGT
SSS
GGGGGG



TTS
TTTTT
TTS
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   194.....200.........210.........220.........230.........240.........250.........260.........270...
 
   149150.........160.........170.........180......
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . DPTYGVLSRQDLDQLQAGARVDVVDDKRNPMDFVLWKM. . . . . . . . . . . . . . . . . . .
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Template Conservation         
  
       
          
     
    


 
   


   
        
     

  
      
Template Sequence  QVLKTFPGKALEGLPYTPPYPQALEKGYFVVLADYVSQEDGTGIVHQAPAFGAEDLETARVYGLPLLKTVDEEGKLLVEP
Template Known Secondary structure 

TT
BB

SS



SS
SB
TT

SSSS
S


TTS
TT





B
TTSBB
SGG
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   274.....280.........290.........300.........310.........320.........330.........340.........350...
 
  
Predicted Secondary structure  ................................................................................
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Query Conservation  ................................................................................
Template Conservation    
    

   
   
   
 
              
    
      



                   
       
Template Sequence  FKGLYFREANRAILRDLRGRGLLFKEESYLHSYPHCWRCSTPLMYYATESWFIKNTLFKDELIRNNQEIHWVPPHIKEGR
Template Known Secondary structure  GTT
BTT
B
SSS

B



GGGGSSSGGGTTTT
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   354.....360.........370.........380.........390.........400.........410.........420.........430...
 
   187..190.........200...
Predicted Secondary structure  .......
















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Query Sequence  . . . . . . . SKEGEPSWPSPWGAGRP. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Query Conservation  .......           

 
 
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Template Conservation      
  
 

 




 

 


                                                    
  
Template Sequence  YGEWLKNLVDWALSRNRYWGTPLPIWVCQACGKEEAIGSFQELKARATKPLPEPFDPHRPYVDQVELACACGGTMRRVPY
Template Known Secondary structure  TT




B

SSS
B

SSSS



SBSS


SS


STT

TTSS
S
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   434.....440.........450.........460.........470.........480.........490.........500.........510...
 
   204.....210.... .....220.........230.........240.........250.........260. .......
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Query Sequence  . . . GWHIECSAMNC. . . . . . . . . . . KQLGNHFDIHGGGSDLMFPHHENEIAQSTCAHDGQYVNYWMHSGMVM. VDREKMS
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Template Conservation 


 



                      
 
    
 
    
               
   
  

 

   
 


Template Sequence  VIDVWYDSGAMPFASLHYPFEHEEVFRESFPADFIAEGIDQTRGWFNSLHQLGVMLFGSIAFKNVICHGLILDEKGQKMS
Template Known Secondary structure  B

TTTTTTS
SSBSBGGGGGTSS
SBS


TTSS


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   514.....520.........530.........540.........550.........560.........570.........580.........590...
 
   269270.........280.........290..... ....300.........310.... .....320.........330..
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Query Sequence  KSLGNFFTVRDVLKYYDAETVRYFLMS. GHYRSQLNYSEENLKQARA. ALERLYTALRGTDKTVAP. . . . . . . . . . . . . .
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Template Conservation 

 

 
 
   
  



 

  
        
  
    
         

 
                         
Template Sequence  KSKGNVVDPWDIIRKFGADALRWYIYVSAPPEADRRFGPNLVRETVRDYFLTLWNVYSFFVTYANLDRPDLKNPPPPEKR
Template Known Secondary structure  TTTT



TTT
S
SSS


T


TTS


STTS
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   594.....600.........610.........620.........630.........640.........650.........660.........670...
 
   333......340.........350.........360..... ....370....... ..380.........
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Query Sequence  . . . . . . . . AGGEAFEARFIEAMDDDFNTPEAYSVLFDMARE. . VNRLKAEDMAAA. . . . . . . . . . . . . NAMASHLRKLSA
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Template Conservation     
  

  
      
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Template Sequence  PEMDRWLLARMQDLIQRVTEAL. EAYDPTTSARALRDFVVEDLSQWYVRRNRRRFWKNEDALDREAAYATLYEALVLVAT
Template Known Secondary structure 
.TT
SSTTTT
TTTSSTT
Template Predicted Secondary structure 
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   674.....680.........690..... ....700.........710.........720.........730.........740.........750..
 
   390.........400... ......410.........420.........430
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Query Sequence  VLGLLEQEPEAFLQ. . . . . . . . . . . . . . . . . . . . . . . SGAQADDSEVAEIEALIQQRLDARKAK
Query Conservation 


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Template Conservation 

 
  
  




  
          

    

                    
   

   
Template Sequence  LAAPFTPFLAEVLWQNLVRSVRLEAKESVHLADWPEADPALADEALVAQMRAVLKVVDLARAAR
Template Known Secondary structure  TTTSTTTTTTSTTS
SSGGGS





TTT

TT
T
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   753......760.........770.........780.........790.........800.........810......
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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