Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	S	T	T	H	N	V	P	Q	G	D	L	V	L	R	T	L	A	M	P	A	D	T	N	A	N	G	D	I	F	G	G	W	L	M	S	Q	M	D	I	G	G	A	I	L	A	K	E	I	A	H	G	R	V	V	T	V	R	V	E
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		G	M	T	F	L	R	P	V	A	V	G	D	V	V	C	C	Y	A	R	C	V	Q	K	G	T	T	S	V	S	I	N	I	E	V	W	V	K	K	V	A	S	E	P	I	G	Q	R	Y	K	A	T	E	A	L	F	K	Y	V	A	V
Secondary structure
SS confidence
Disorder																																										?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.
Sequence		D	P	E	G	K	P	R	A	L	P	V	E
Secondary structure
SS confidence
Disorder							?	?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1yli chain A domain 1 Region: 6 - 132 Aligned: 127 Modelled: 127 Confidence: 100.0% Identity: 68% Fold: Thioesterase/thiol ester dehydrase-isomerase Superfamily: Thioesterase/thiol ester dehydrase-isomerase Family: 4HBT-like Phyre2 PDB 3d6l chain A Region: 8 - 132 Aligned: 125 Modelled: 125 Confidence: 100.0% Identity: 41% PDB header:hydrolase Chain: A: PDB Molecule:putative hydrolase; PDBTitle: crystal structure of cj0915, a hexameric hotdog fold2 thioesterase of campylobacter jejuni Phyre2 PDB 1y7u chain A domain 1 Region: 5 - 131 Aligned: 124 Modelled: 127 Confidence: 100.0% Identity: 24% Fold: Thioesterase/thiol ester dehydrase-isomerase Superfamily: Thioesterase/thiol ester dehydrase-isomerase Family: 4HBT-like Phyre2 PDB 2qq2 chain C Region: 2 - 131 Aligned: 128 Modelled: 130 Confidence: 100.0% Identity: 27% PDB header:hydrolase Chain: C: PDB Molecule:cytosolic acyl coenzyme a thioester hydrolase; PDBTitle: crystal structure of c-terminal domain of human acyl-coa thioesterase2 7 Phyre2 PDB 1vpm chain A Region: 6 - 131 Aligned: 123 Modelled: 126 Confidence: 100.0% Identity: 31% Fold: Thioesterase/thiol ester dehydrase-isomerase Superfamily: Thioesterase/thiol ester dehydrase-isomerase Family: 4HBT-like Phyre2 PDB 2eis chain A Region: 11 - 131 Aligned: 119 Modelled: 121 Confidence: 100.0% Identity: 33% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein tthb207; PDBTitle: x-ray structure of acyl-coa hydrolase-like protein, tt1379, from2 thermus thermophilus hb8 Phyre2 PDB 2gvh chain A domain 1 Region: 8 - 131 Aligned: 121 Modelled: 124 Confidence: 100.0% Identity: 25% Fold: Thioesterase/thiol ester dehydrase-isomerase Superfamily: Thioesterase/thiol ester dehydrase-isomerase Family: 4HBT-like Phyre2 PDB 2gvh chain C Region: 3 - 132 Aligned: 127 Modelled: 130 Confidence: 100.0% Identity: 24% PDB header:hydrolase Chain: C: PDB Molecule:agr_l_2016p; PDBTitle: crystal structure of acyl-coa hydrolase (15159470) from agrobacterium2 tumefaciens at 2.65 a resolution Phyre2 PDB 3b7k chain A Region: 8 - 132 Aligned: 122 Modelled: 125 Confidence: 100.0% Identity: 24% PDB header:hydrolase Chain: A: PDB Molecule:acyl-coenzyme a thioesterase 12; PDBTitle: human acyl-coenzyme a thioesterase 12 Phyre2 PDB 2gvh chain A domain 2 Region: 12 - 129 Aligned: 112 Modelled: 115 Confidence: 100.0% Identity: 25% Fold: Thioesterase/thiol ester dehydrase-isomerase Superfamily: Thioesterase/thiol ester dehydrase-isomerase Family: 4HBT-like Phyre2 PDB 2v1o chain F Region: 16 - 131 Aligned: 113 Modelled: 116 Confidence: 100.0% Identity: 25% PDB header:hydrolase Chain: F: PDB Molecule:cytosolic acyl coenzyme a thioester hydrolase; PDBTitle: crystal structure of n-terminal domain of acyl-coa2 thioesterase 7 Phyre2 PDB 2f0x chain A domain 1 Region: 6 - 117 Aligned: 105 Modelled: 112 Confidence: 99.9% Identity: 16% Fold: Thioesterase/thiol ester dehydrase-isomerase Superfamily: Thioesterase/thiol ester dehydrase-isomerase Family: PaaI/YdiI-like Phyre2 PDB 3lwg chain B Region: 6 - 123 Aligned: 105 Modelled: 118 Confidence: 99.9% Identity: 10% PDB header:unknown function Chain: B: PDB Molecule:hp0420 homologue; PDBTitle: crystal structure of hp0420-homologue c46a from helicobacter2 felis Phyre2 PDB 2qwz chain B Region: 5 - 118 Aligned: 107 Modelled: 114 Confidence: 99.9% Identity: 16% PDB header:hydrolase Chain: B: PDB Molecule:phenylacetic acid degradation-related protein; PDBTitle: crystal structure of a putative thioesterase (tm1040_1390) from2 silicibacter sp. tm1040 at 2.15 a resolution Phyre2 PDB 3e1e chain E Region: 5 - 120 Aligned: 110 Modelled: 115 Confidence: 99.8% Identity: 18% PDB header:hydrolase Chain: E: PDB Molecule:thioesterase family protein; PDBTitle: crystal structure of a thioesterase family protein from2 silicibacter pomeroyi. northeast structural genomics3 target sir180a Phyre2 PDB 1ixl chain A Region: 6 - 123 Aligned: 105 Modelled: 118 Confidence: 99.8% Identity: 16% Fold: Thioesterase/thiol ester dehydrase-isomerase Superfamily: Thioesterase/thiol ester dehydrase-isomerase Family: PaaI/YdiI-like Phyre2 PDB 2hbo chain A domain 1 Region: 5 - 132 Aligned: 115 Modelled: 128 Confidence: 99.8% Identity: 22% Fold: Thioesterase/thiol ester dehydrase-isomerase Superfamily: Thioesterase/thiol ester dehydrase-isomerase Family: PaaI/YdiI-like Phyre2 PDB 2h4u chain A domain 1 Region: 5 - 117 Aligned: 106 Modelled: 113 Confidence: 99.8% Identity: 16% Fold: Thioesterase/thiol ester dehydrase-isomerase Superfamily: Thioesterase/thiol ester dehydrase-isomerase Family: PaaI/YdiI-like Phyre2 PDB 3bnv chain D Region: 6 - 123 Aligned: 105 Modelled: 118 Confidence: 99.8% Identity: 16% PDB header:unknown function Chain: D: PDB Molecule:cj0977; PDBTitle: crystal structure of cj0977, a sigma28-regulated virulence protein2 from campylobacter jejuni. Phyre2 PDB 2cy9 chain A domain 1 Region: 6 - 117 Aligned: 101 Modelled: 112 Confidence: 99.8% Identity: 15% Fold: Thioesterase/thiol ester dehydrase-isomerase Superfamily: Thioesterase/thiol ester dehydrase-isomerase Family: PaaI/YdiI-like Phyre2 1 d1ylia1 2 c3d6lA_ 3 d1y7ua1 4 c2qq2C_ 5 d1vpma_ 6 c2eisA_ 7 d2gvha1 8 c2gvhC_ 9 c3b7kA_ 10 d2gvha2 11 c2v1oF_ 12 d2f0xa1 13 c3lwgB_ 14 c2qwzB_ 15 c3e1eE_ 16 d1ixla_ 17 d2hboa1 18 d2h4ua1 19 c3bnvD_ 20 d2cy9a1 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d1ylia1 100.0 68 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:4HBT-like 2 c3d6lA_ 100.0 41 PDB header:hydrolase Chain: A: PDB Molecule:putative hydrolase; PDBTitle: crystal structure of cj0915, a hexameric hotdog fold2 thioesterase of campylobacter jejuni 3 d1y7ua1 100.0 24 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:4HBT-like 4 c2qq2C_ 100.0 27 PDB header:hydrolase Chain: C: PDB Molecule:cytosolic acyl coenzyme a thioester hydrolase; PDBTitle: crystal structure of c-terminal domain of human acyl-coa thioesterase2 7 5 d1vpma_ 100.0 31 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:4HBT-like 6 c2eisA_ 100.0 33 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein tthb207; PDBTitle: x-ray structure of acyl-coa hydrolase-like protein, tt1379, from2 thermus thermophilus hb8 7 d2gvha1 100.0 25 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:4HBT-like 8 c2gvhC_ 100.0 24 PDB header:hydrolase Chain: C: PDB Molecule:agr_l_2016p; PDBTitle: crystal structure of acyl-coa hydrolase (15159470) from agrobacterium2 tumefaciens at 2.65 a resolution 9 c3b7kA_ 100.0 24 PDB header:hydrolase Chain: A: PDB Molecule:acyl-coenzyme a thioesterase 12; PDBTitle: human acyl-coenzyme a thioesterase 12 10 d2gvha2 100.0 25 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:4HBT-like 11 c2v1oF_ 100.0 25 PDB header:hydrolase Chain: F: PDB Molecule:cytosolic acyl coenzyme a thioester hydrolase; PDBTitle: crystal structure of n-terminal domain of acyl-coa2 thioesterase 7 12 d2f0xa1 99.9 16 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:PaaI/YdiI-like 13 c3lwgB_ 99.9 10 PDB header:unknown function Chain: B: PDB Molecule:hp0420 homologue; PDBTitle: crystal structure of hp0420-homologue c46a from helicobacter2 felis 14 c2qwzB_ 99.9 16 PDB header:hydrolase Chain: B: PDB Molecule:phenylacetic acid degradation-related protein; PDBTitle: crystal structure of a putative thioesterase (tm1040_1390) from2 silicibacter sp. tm1040 at 2.15 a resolution 15 c3e1eE_ 99.8 18 PDB header:hydrolase Chain: E: PDB Molecule:thioesterase family protein; PDBTitle: crystal structure of a thioesterase family protein from2 silicibacter pomeroyi. northeast structural genomics3 target sir180a 16 d1ixla_ 99.8 16 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:PaaI/YdiI-like 17 d2hboa1 99.8 22 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:PaaI/YdiI-like 18 d2h4ua1 99.8 16 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:PaaI/YdiI-like 19 c3bnvD_ 99.8 16 PDB header:unknown function Chain: D: PDB Molecule:cj0977; PDBTitle: crystal structure of cj0977, a sigma28-regulated virulence protein2 from campylobacter jejuni. 20 d2cy9a1 99.8 15 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:PaaI/YdiI-like 21 c2pimA_ not modelled 99.8 22 PDB header:hydrolase Chain: A: PDB Molecule:phenylacetic acid degradation-related protein; PDBTitle: crystal structure of a putative thioesterase, phenylacetic acid2 degradation-related protein (reut_b4779) from ralstonia eutropha3 jmp134 at 2.20 a resolution 22 c3lbeA_ not modelled 99.8 17 PDB header:unknown function Chain: A: PDB Molecule:putative uncharacterized protein smu.793; PDBTitle: the crystal structure of smu.793 from streptococcus mutans ua159 bound2 to acetyl coa 23 d1vh5a_ not modelled 99.8 13 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:PaaI/YdiI-like 24 d1wlua1 not modelled 99.8 20 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:PaaI/YdiI-like 25 d1sc0a_ not modelled 99.8 14 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:PaaI/YdiI-like 26 c3gekA_ not modelled 99.8 13 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:putative thioesterase yhda; PDBTitle: crystal structure of putative thioesterase yhda from lactococcus2 lactis. northeast structural genomics consortium target kr113 27 d1zkia1 not modelled 99.8 21 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:PaaI/YdiI-like 28 c3nwzD_ not modelled 99.8 14 PDB header:structural genomics, unknown function Chain: D: PDB Molecule:bh2602 protein; PDBTitle: crystal structure of bh2602 protein from bacillus halodurans with coa,2 northeast structural genomics consortium target bhr199 29 d1vh9a_ not modelled 99.8 18 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:PaaI/YdiI-like 30 c3f1tB_ not modelled 99.8 14 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein q9i3c8_pseae; PDBTitle: crystal structure of the q9i3c8_pseae protein from pseudomonas2 aeruginosa. northeast structural genomics consortium target par319a. 31 d2fs2a1 not modelled 99.8 20 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:PaaI/YdiI-like 32 d2f41a1 not modelled 99.8 14 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:PaaI/YdiI-like 33 c3s4kA_ not modelled 99.8 14 PDB header:hydrolase Chain: A: PDB Molecule:putative esterase rv1847/mt1895; PDBTitle: structure of a putative esterase rv1847/mt1895 from mycobacterium2 tuberculosis 34 d1q4ua_ not modelled 99.8 12 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:PaaI/YdiI-like 35 c3e8pA_ not modelled 99.7 16 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of the protein q8e9m7 from shewanella2 oneidensis related to thioesterase superfamily. northeast3 structural genomics consortium target sor246. 36 c3hduB_ not modelled 99.7 19 PDB header:hydrolase Chain: B: PDB Molecule:putative thioesterase; PDBTitle: crystal structure of a putative thioesterase (syn_01977) from2 syntrophus aciditrophicus sb at 2.50 a resolution 37 c3dkzA_ not modelled 99.7 22 PDB header:hydrolase Chain: A: PDB Molecule:thioesterase superfamily protein; PDBTitle: crystal structure of the q7w9w5_borpa protein from2 bordetella parapertussis. northeast structural genomics3 consortium target bpr208c. 38 c2f3xA_ not modelled 99.7 15 PDB header:gene regulation Chain: A: PDB Molecule:transcription factor fapr; PDBTitle: crystal structure of fapr (in complex with effector)- a2 global regulator of fatty acid biosynthesis in b. subtilis 39 c3e29C_ not modelled 99.7 13 PDB header:structural genomics, unknown function Chain: C: PDB Molecule:uncharacterized protein q7we92_borbr; PDBTitle: x-ray structure of the protein q7we92_borbr from thioesterase2 superfamily. northeast structural genomics consortium target bor214a. 40 c2prxB_ not modelled 99.7 17 PDB header:hydrolase Chain: B: PDB Molecule:thioesterase superfamily protein; PDBTitle: crystal structure of thioesterase superfamily protein (zp_00837258.1)2 from shewanella loihica pv-4 at 1.65 a resolution 41 d2ov9a1 not modelled 99.6 8 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:PaaI/YdiI-like 42 d1t82a_ not modelled 99.6 16 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:PaaI/YdiI-like 43 d1sh8a_ not modelled 99.6 18 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:PaaI/YdiI-like 44 d1yoca1 not modelled 99.6 9 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:PaaI/YdiI-like 45 c3lmbA_ not modelled 99.5 14 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: the crystal structure of the protein olei01261 with unknown function2 from chlorobaculum tepidum tls 46 c3hm0C_ not modelled 99.5 19 PDB header:hydrolase Chain: C: PDB Molecule:probable thioesterase; PDBTitle: crystal structure of probable thioesterase from bartonella2 henselae 47 d1njka_ not modelled 99.5 15 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:4HBT-like 48 d2nuja1 not modelled 99.5 13 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:4HBT-like 49 c2pzhC_ not modelled 99.5 17 PDB header:hydrolase Chain: C: PDB Molecule:hypothetical protein hp_0496; PDBTitle: ybgc thioesterase (hp0496) from helicobacter pylori 50 c2w3xE_ not modelled 99.4 14 PDB header:hydrolase Chain: E: PDB Molecule:cale7; PDBTitle: crystal structure of a bifunctional hotdog fold2 thioesterase in enediyne biosynthesis, cale7 51 d2gf6a1 not modelled 99.4 18 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:4HBT-like 52 c2xflB_ not modelled 99.4 17 PDB header:hydrolase Chain: B: PDB Molecule:dyne7; PDBTitle: induced-fit and allosteric effects upon polyene binding2 revealed by crystal structures of the dynemicin3 thioesterase 53 d2o5ua1 not modelled 99.4 21 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:4HBT-like 54 d2cyea1 not modelled 99.4 22 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:4HBT-like 55 c2egiE_ not modelled 99.3 15 PDB header:structural genomics, unknown function Chain: E: PDB Molecule:hypothetical protein aq_1494; PDBTitle: crystal structure of a hypothetical protein(aq1494) from aquifex2 aeolicus 56 d2hx5a1 not modelled 99.3 22 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:4HBT-like 57 d2hlja1 not modelled 99.3 14 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:4HBT-like 58 d1s5ua_ not modelled 99.3 21 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:4HBT-like 59 d1z54a1 not modelled 99.3 18 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:4HBT-like 60 d1lo7a_ not modelled 99.3 12 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:4HBT-like 61 d2oafa1 not modelled 99.2 17 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:4HBT-like 62 d2alia1 not modelled 99.2 16 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:4HBT-like 63 c2aliA_ not modelled 99.2 16 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein pa2801; PDBTitle: structure of protein of unknown function pa2801 from pseudomonas2 aeruginosa, putative thioesterase 64 d2oiwa1 not modelled 99.2 17 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:4HBT-like 65 c3ck1B_ not modelled 99.2 19 PDB header:hydrolase Chain: B: PDB Molecule:putative thioesterase; PDBTitle: crystal structure of a putative thioesterase (reut_a2179) from2 ralstonia eutropha jmp134 at 1.74 a resolution 66 d2essa1 not modelled 99.1 14 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:Acyl-ACP thioesterase-like 67 d2owna1 not modelled 99.1 10 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:Acyl-ACP thioesterase-like 68 d2fuja1 not modelled 99.1 13 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:4HBT-like 69 c2essA_ not modelled 98.9 14 PDB header:hydrolase Chain: A: PDB Molecule:acyl-acp thioesterase; PDBTitle: crystal structure of an acyl-acp thioesterase (np_810988.1) from2 bacteroides thetaiotaomicron vpi-5482 at 1.90 a resolution 70 d2cwza1 not modelled 98.8 16 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:TTHA0967-like 71 c2ownA_ not modelled 98.8 11 PDB header:hydrolase Chain: A: PDB Molecule:putative oleoyl-[acyl-carrier protein] thioesterase; PDBTitle: crystal structure of oleoyl thioesterase (putative) (np_784467.1) from2 lactobacillus plantarum at 2.00 a resolution 72 c3bbjA_ not modelled 98.3 15 PDB header:hydrolase Chain: A: PDB Molecule:putative thioesterase ii; PDBTitle: crystal structure of a putative thioesterase ii (tfu_2367) from2 thermobifida fusca yx at 2.45 a resolution 73 c3rqbB_ not modelled 98.3 14 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of conserved protein of unknown function with hot2 dog fold from alicyclobacillus acidocaldarius 74 c3qooA_ not modelled 98.3 15 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of hot-dog-like taci_0573 protein from2 thermanaerovibrio acidaminovorans 75 d1c8ua1 not modelled 98.2 13 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:Acyl-CoA thioesterase 76 c1c8uA_ not modelled 98.2 16 PDB header:hydrolase Chain: A: PDB Molecule:acyl-coa thioesterase ii; PDBTitle: crystal structure of the e.coli thioesterase ii, a2 homologue of the human nef-binding enzyme 77 c3kuvB_ not modelled 98.2 9 PDB header:hydrolase Chain: B: PDB Molecule:fluoroacetyl coenzyme a thioesterase; PDBTitle: structural basis of the activity and substrate specificity of the2 fluoroacetyl-coa thioesterase flk - t42s mutant in complex with3 acetate. 78 c3rd7A_ not modelled 98.2 16 PDB header:hydrolase Chain: A: PDB Molecule:acyl-coa thioesterase; PDBTitle: crystal structure of acyl-coa thioesterase from mycobacterium avium 79 c3cjyA_ not modelled 98.0 14 PDB header:hydrolase Chain: A: PDB Molecule:putative thioesterase; PDBTitle: crystal structure of putative thioesterase (yp_496845.1) from2 novosphingobium aromaticivorans dsm 12444 at 1.70 a resolution 80 d2bi0a1 not modelled 98.0 16 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:MaoC-like 81 d2owna2 not modelled 97.8 9 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:Acyl-ACP thioesterase-like 82 d2q78a1 not modelled 97.8 21 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:TTHA0967-like 83 d1tbua1 not modelled 97.8 13 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:Acyl-CoA thioesterase 84 c3ir3B_ not modelled 97.7 14 PDB header:lyase Chain: B: PDB Molecule:3-hydroxyacyl-thioester dehydratase 2; PDBTitle: crystal structure of human 3-hydroxyacyl-thioester dehydratase 22 (htd2) 85 c3d6xA_ not modelled 97.4 18 PDB header:lyase Chain: A: PDB Molecule:(3r)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase; PDBTitle: crystal structure of campylobacter jejuni fabz 86 c2glvA_ not modelled 97.4 17 PDB header:lyase Chain: A: PDB Molecule:(3r)-hydroxymyristoyl-acyl carrier protein PDBTitle: crystal structure of (3r)-hydroxyacyl-acyl carrier protein2 dehydratase(fabz) mutant(y100a) from helicobacter pylori 87 d1iq6a_ not modelled 97.3 20 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:MaoC-like 88 d2c2ia1 not modelled 97.3 17 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:MaoC-like 89 c2bi0A_ not modelled 97.3 16 PDB header:hypothetical protein Chain: A: PDB Molecule:hypothetical protein rv0216; PDBTitle: rv0216, a conserved hypothetical protein from mycobacterium2 tuberculosis that is essential for bacterial survival3 during infection, has a double hotdogfold 90 d2essa2 not modelled 97.1 15 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:Acyl-ACP thioesterase-like 91 d2b3na1 not modelled 97.0 16 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:MaoC-like 92 c3exzA_ not modelled 97.0 10 PDB header:lyase Chain: A: PDB Molecule:maoc-like dehydratase; PDBTitle: crystal structure of the maoc-like dehydratase from rhodospirillum2 rubrum. northeast structural genomics consortium target rrr103a. 93 d2bi0a2 not modelled 96.9 13 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:MaoC-like 94 d1q6wa_ not modelled 96.9 21 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:MaoC-like 95 d1z6ba1 not modelled 96.6 13 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:FabZ-like 96 d1u1za_ not modelled 95.8 12 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:FabZ-like 97 c3esiD_ not modelled 95.6 12 PDB header:structural genomics, unknown function Chain: D: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of an uncharacterized protein from2 erwinia carotovora subsp. atroseptica. northeast3 structural genomics target ewr179 98 c3khpB_ not modelled 95.2 20 PDB header:oxidoreductase Chain: B: PDB Molecule:maoc family protein; PDBTitle: crystal structure of a possible dehydrogenase from2 mycobacterium tuberculosis at 2.3a resolution 99 d1c8ua2 not modelled 95.1 10 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:Acyl-CoA thioesterase 100 c3kh8B_ not modelled 93.9 19 PDB header:lyase Chain: B: PDB Molecule:maoc-like dehydratase; PDBTitle: crystal structure of maoc-like dehydratase from phytophthora capsici 101 d1pn2a2 not modelled 92.1 12 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:MaoC-like 102 c2cdhT_ not modelled 88.6 16 PDB header:transferase Chain: T: PDB Molecule:dehydratase; PDBTitle: architecture of the thermomyces lanuginosus fungal fatty2 acid synthase at 5 angstrom resolution. 103 d1mkaa_ not modelled 87.3 17 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:beta-Hydroxydecanol thiol ester dehydrase 104 d1s9ca1 not modelled 86.1 16 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:MaoC-like 105 d1pn2a1 not modelled 84.6 5 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:MaoC-like 106 c1s9cK_ not modelled 82.1 14 PDB header:lyase Chain: K: PDB Molecule:peroxisomal multifunctional enzyme type 2; PDBTitle: crystal structure analysis of the 2-enoyl-coa hydratase 22 domain of human peroxisomal multifunctional enzyme type 2 107 c1pn2D_ not modelled 74.6 18 PDB header:lyase Chain: D: PDB Molecule:peroxisomal hydratase-dehydrogenase-epimerase; PDBTitle: crystal structure analysis of the selenomethionine labelled2 2-enoyl-coa hydratase 2 domain of candida tropicalis3 multifunctional enzyme type 2 108 c2cf2L_ not modelled 72.6 15 PDB header:transferase Chain: L: PDB Molecule:fatty acid synthase, dh domain; PDBTitle: architecture of mammalian fatty acid synthase 109 d1s9ca2 not modelled 62.6 15 Fold:Thioesterase/thiol ester dehydrase-isomerase Superfamily:Thioesterase/thiol ester dehydrase-isomerase Family:MaoC-like 110 c3omlA_ not modelled 55.3 12 PDB header:oxidoreductase, hydrolase Chain: A: PDB Molecule:peroxisomal multifunctional enzyme type 2, cg3415; PDBTitle: structure of full-length peroxisomal multifunctional enzyme type 22 from drosophila melanogaster

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0