Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP33228
DateThu Jan 5 11:51:27 GMT 2012
Unique Job IDc8312b3c54d042cf

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c2l42A_
Top template information
PDB header:protein binding
Chain: A: PDB Molecule:dna-binding protein rap1;
PDBTitle: the solution structure of rap1 brct domain from saccharomyces2 cerevisiae
Confidence and coverage
Confidence: 12.7% Coverage: 9%
24 residues ( 9% of your sequence) have been modelled with 12.7% confidence by the single highest scoring template.
You may wish to submit your sequence to Phyrealarm. This will automatically scan your sequence every week for new potential templates as they appear in the Phyre2 library.
Please note: You must be registered and logged in to use Phyrealarm.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MTKQPPIAKADLQKTQGNRAPAAVKNSDVISFINQPSMKEQLAAALPRHMTAERMIRIAT
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Disorder  ????????



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   .........70.........80.........90.........100.........110.........120
Sequence  TEIRKVPALGNCDTMSFVSAIVQCSQLGLEPGSALGHAYLLPFGNKNEKSGKKNVQLIIG
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   .........130.........140.........150.........160.........170.........180
Sequence  YRGMIDLARRSGQIASLSARVVREGDEFSFEFGLDEKLIHRPGENEDAPVTHVYAVARLK
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   .........190.........200.........210.........220.........230.........240
Sequence  DGGTQFEVMTRKQIELVRSLSKAGNNGPWVTHWEEMAKKTAIRRLFKYLPVSIEIQRAVS
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   .........250.........260.........
Sequence  MDEKEPLTIDPADSSVLTGEYSVIDNSEE
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Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 2l42 chain A

3D model

Region: 76 - 105
Aligned: 24
Modelled: 30
Confidence: 12.7%
Identity: 33%
PDB header:protein binding
Chain: A: PDB Molecule:dna-binding protein rap1;
PDBTitle: the solution structure of rap1 brct domain from saccharomyces2 cerevisiae

Phyre2

PDB 2bbk chain L

3D model

Region: 92 - 104
Aligned: 13
Modelled: 13
Confidence: 9.1%
Identity: 23%
Fold: Methylamine dehydrogenase, L chain
Superfamily: Methylamine dehydrogenase, L chain
Family: Methylamine dehydrogenase, L chain

Phyre2

PDB 3c75 chain L

3D model

Region: 92 - 104
Aligned: 13
Modelled: 13
Confidence: 8.9%
Identity: 23%
PDB header:oxidoreductase
Chain: L: PDB Molecule:methylamine dehydrogenase light chain;
PDBTitle: paracoccus versutus methylamine dehydrogenase in complex2 with amicyanin

Phyre2

PDB 2iur chain D

3D model

Region: 92 - 104
Aligned: 13
Modelled: 13
Confidence: 8.8%
Identity: 23%
PDB header:oxidoreductase
Chain: D: PDB Molecule:aromatic amine dehydrogenase beta subunit;
PDBTitle: crystal structure of n-quinol form of aromatic amine2 dehydrogenase (aadh) from alcaligenes faecalis, form a3 cocrystal

Phyre2

PDB 2di0 chain A domain 1

3D model

Region: 36 - 92
Aligned: 45
Modelled: 57
Confidence: 8.6%
Identity: 22%
Fold: RuvA C-terminal domain-like
Superfamily: UBA-like
Family: CUE domain

Phyre2

PDB 1fi8 chain F

3D model

Region: 94 - 106
Aligned: 13
Modelled: 13
Confidence: 6.7%
Identity: 38%
PDB header:hydrolase/hydrolase inhibitor
Chain: F: PDB Molecule:ecotin;
PDBTitle: rat granzyme b [n66q] complexed to ecotin [81-84 iepd]

Phyre2

PDB 2xvc chain A

3D model

Region: 118 - 137
Aligned: 20
Modelled: 20
Confidence: 5.2%
Identity: 20%
PDB header:cell cycle
Chain: A: PDB Molecule:escrt-iii;
PDBTitle: molecular and structural basis of escrt-iii recruitment to2 membranes during archaeal cell division

Phyre2
1

c2l42A_
2

d2bbkl_
3

c3c75L_
4

c2iurD_
5

d2di0a1
6

c1fi8F_
7

c2xvcA_



Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c2l42A_



12.7 33 PDB header:protein binding
Chain: A: PDB Molecule:dna-binding protein rap1;
PDBTitle: the solution structure of rap1 brct domain from saccharomyces2 cerevisiae
2d2bbkl_



9.1 23 Fold:Methylamine dehydrogenase, L chain
Superfamily:Methylamine dehydrogenase, L chain
Family:Methylamine dehydrogenase, L chain
3c3c75L_



8.9 23 PDB header:oxidoreductase
Chain: L: PDB Molecule:methylamine dehydrogenase light chain;
PDBTitle: paracoccus versutus methylamine dehydrogenase in complex2 with amicyanin
4c2iurD_



8.8 23 PDB header:oxidoreductase
Chain: D: PDB Molecule:aromatic amine dehydrogenase beta subunit;
PDBTitle: crystal structure of n-quinol form of aromatic amine2 dehydrogenase (aadh) from alcaligenes faecalis, form a3 cocrystal
5d2di0a1



8.6 22 Fold:RuvA C-terminal domain-like
Superfamily:UBA-like
Family:CUE domain
6c1fi8F_



6.7 38 PDB header:hydrolase/hydrolase inhibitor
Chain: F: PDB Molecule:ecotin;
PDBTitle: rat granzyme b [n66q] complexed to ecotin [81-84 iepd]
7c2xvcA_



5.2 20 PDB header:cell cycle
Chain: A: PDB Molecule:escrt-iii;
PDBTitle: molecular and structural basis of escrt-iii recruitment to2 membranes during archaeal cell division

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite



Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0