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Job DescriptionP26612
Confidence90.73%DateThu Jan 5 11:42:59 GMT 2012
Rank239Aligned Residues172
% Identity10%Templatec1nouA_
PDB info PDB header:hydrolaseChain: A: PDB Molecule:beta-hexosaminidase beta chain; PDBTitle: native human lysosomal beta-hexosaminidase isoform b
Resolution2.40 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   7..10.........20.........30.........40.........50.........60.........70.........80......
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Query Sequence  LQCFHWYYPEGGKLWPELAERADGFNDIGINMVWLPPAYKGASGGYSVGYDSYDLFDLGEFDQKGSIPTKYGDKAQLLAA
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Template Sequence  HRGILIDTSRHYLPVKIILKTLDAMAFNKFNVLHW. . . . . HIVDDQSFPYQSITFPELSNKGSYSL. SHVY. TPNDVRMV
Template Known Secondary structure  SSSS


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   202.......210.........220.........230...... ...240.........250.........260.. .... ...270....
 
   87..90.........100. ........110.........120.........130.........140.........150.........160.....
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Query Sequence  IDALKRNDIAVLLDV. VVNHKMGADEKEAIRVQRVNADDRTQIDEEIIECEGWTRYTFPARAGQYSQFIWDFKCFSGIDH
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Template Sequence  IEYARLRGIRVLPEFDTPGHTL. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Template Known Secondary structure  TT
SSS
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   275....280.........290......
 
   166...170.........180.........190.........200.........210.........220.........230......
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Query Sequence  IENPDEDGIFKIVNDYTGEGWNDQVDDELGNFDYLMGENIDFRNHAVTEEIKYWARWVMEQTQCDGFRLDA. . . . . . . . .
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Template Sequence  . . . . . . . . . . . . . . . . . . SWGKGQKDLLTPCYSLDSFGPINPTLNTTYSFLTTFFKEISEVFPDQFIHLGGDEVEFKCWE
Template Known Secondary structure  ..................TSTT





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   297..300.........310.........320.........330.........340.........350........
 
   237..240.........250.........260.
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Query Sequence  . . . . . . . . . . . . . . . . . VKHIPAWFYKEWIEHVQEVAPKPLF
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Template Sequence  SNPKIQDFMRQKGFGTDFKKLESFYIQKVLDIIATINKGSIV
Template Known Secondary structure 
TT
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TTT
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   363......370.........380.........390.........400....
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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