Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	E	I	S	L	L	Q	A	F	A	L	G	I	I	A	F	I	A	G	L	D	M	F	N	G	L	T	H	M	H	R	P	V	V	L	G	P	L	V	G	L	V	L	G	D	L	H	T	G	I	L	T	G	G	T	L	E	L	V	W
Secondary structure
SS confidence
Disorder		?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		M	G	L	A	P	L	A	G	A	Q	P	P	N	V	I	I	G	T	I	V	G	T	A	F	A	I	T	T	G	V	K	P	D	V	A	V	G	V	A	V	P	F	A	V	A	V	Q	M	G	I	T	F	L	F	S	V	M	S	G	V
Secondary structure
SS confidence
Disorder						?	?																						?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.
Sequence		M	S	R	C	D	L	A	T	N	P	R	R	I
Secondary structure
SS confidence
Disorder											?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1cii chain A Region: 69 - 120 Aligned: 51 Modelled: 52 Confidence: 40.2% Identity: 16% PDB header:transmembrane protein Chain: A: PDB Molecule:colicin ia; PDBTitle: colicin ia Phyre2 PDB 2l35 chain B Region: 30 - 52 Aligned: 23 Modelled: 23 Confidence: 37.0% Identity: 39% PDB header:protein binding Chain: B: PDB Molecule:tyro protein tyrosine kinase-binding protein; PDBTitle: structure of the dap12-nkg2c transmembrane heterotrimer Phyre2 PDB 2l34 chain B Region: 30 - 52 Aligned: 23 Modelled: 23 Confidence: 30.9% Identity: 39% PDB header:protein binding Chain: B: PDB Molecule:tyro protein tyrosine kinase-binding protein; PDBTitle: structure of the dap12 transmembrane homodimer Phyre2 PDB 2l34 chain A Region: 36 - 52 Aligned: 17 Modelled: 17 Confidence: 28.3% Identity: 47% PDB header:protein binding Chain: A: PDB Molecule:tyro protein tyrosine kinase-binding protein; PDBTitle: structure of the dap12 transmembrane homodimer Phyre2 PDB 2l35 chain A Region: 36 - 52 Aligned: 17 Modelled: 17 Confidence: 13.0% Identity: 47% PDB header:protein binding Chain: A: PDB Molecule:dap12-nkg2c_tm; PDBTitle: structure of the dap12-nkg2c transmembrane heterotrimer Phyre2 PDB 3a0b chain X Region: 31 - 50 Aligned: 20 Modelled: 20 Confidence: 8.3% Identity: 30% PDB header:electron transport Chain: X: PDB Molecule:photosystem ii reaction center protein x; PDBTitle: crystal structure of br-substituted photosystem ii complex Phyre2 PDB 3a0h chain X Region: 31 - 50 Aligned: 20 Modelled: 20 Confidence: 8.3% Identity: 30% PDB header:electron transport Chain: X: PDB Molecule:photosystem ii reaction center protein x; PDBTitle: crystal structure of i-substituted photosystem ii complex Phyre2 PDB 3a0b chain X Region: 31 - 50 Aligned: 20 Modelled: 20 Confidence: 8.3% Identity: 30% PDB header:electron transport Chain: X: PDB Molecule:photosystem ii reaction center protein x; PDBTitle: crystal structure of br-substituted photosystem ii complex Phyre2 PDB 3a0h chain X Region: 31 - 50 Aligned: 20 Modelled: 20 Confidence: 8.3% Identity: 30% PDB header:electron transport Chain: X: PDB Molecule:photosystem ii reaction center protein x; PDBTitle: crystal structure of i-substituted photosystem ii complex Phyre2 PDB 1s5l chain X Region: 31 - 50 Aligned: 20 Modelled: 20 Confidence: 7.1% Identity: 30% PDB header:photosynthesis Chain: X: PDB Molecule:photosystem ii psbx protein; PDBTitle: architecture of the photosynthetic oxygen evolving center Phyre2 PDB 3fse chain B Region: 43 - 50 Aligned: 8 Modelled: 8 Confidence: 6.1% Identity: 75% PDB header:hydrolase Chain: B: PDB Molecule:two-domain protein containing dj-1/thij/pfpi-like and PDBTitle: crystal structure of a two-domain protein containing dj-1/thij/pfpi-2 like and ferritin-like domains (ava_4496) from anabaena variabilis3 atcc 29413 at 1.90 a resolution Phyre2 PDB 1r7m chain A domain 1 Region: 32 - 45 Aligned: 14 Modelled: 14 Confidence: 5.9% Identity: 36% Fold: Homing endonuclease-like Superfamily: Homing endonucleases Family: Group I mobile intron endonuclease Phyre2 1 c1ciiA_ 2 c2l35B_ 3 c2l34B_ 4 c2l34A_ 5 c2l35A_ 6 c3a0bx_ 7 c3a0hX_ 8 c3a0bX_ 9 c3a0hx_ 10 c1s5lx_ 11 c3fseB_ 12 d1r7ma1

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c1ciiA_ 40.2 16 PDB header:transmembrane protein Chain: A: PDB Molecule:colicin ia; PDBTitle: colicin ia 2 c2l35B_ 37.0 39 PDB header:protein binding Chain: B: PDB Molecule:tyro protein tyrosine kinase-binding protein; PDBTitle: structure of the dap12-nkg2c transmembrane heterotrimer 3 c2l34B_ 30.9 39 PDB header:protein binding Chain: B: PDB Molecule:tyro protein tyrosine kinase-binding protein; PDBTitle: structure of the dap12 transmembrane homodimer 4 c2l34A_ 28.3 47 PDB header:protein binding Chain: A: PDB Molecule:tyro protein tyrosine kinase-binding protein; PDBTitle: structure of the dap12 transmembrane homodimer 5 c2l35A_ 13.0 47 PDB header:protein binding Chain: A: PDB Molecule:dap12-nkg2c_tm; PDBTitle: structure of the dap12-nkg2c transmembrane heterotrimer 6 c3a0bx_ 8.3 30 PDB header:electron transport Chain: X: PDB Molecule:photosystem ii reaction center protein x; PDBTitle: crystal structure of br-substituted photosystem ii complex 7 c3a0hX_ 8.3 30 PDB header:electron transport Chain: X: PDB Molecule:photosystem ii reaction center protein x; PDBTitle: crystal structure of i-substituted photosystem ii complex 8 c3a0bX_ 8.3 30 PDB header:electron transport Chain: X: PDB Molecule:photosystem ii reaction center protein x; PDBTitle: crystal structure of br-substituted photosystem ii complex 9 c3a0hx_ 8.3 30 PDB header:electron transport Chain: X: PDB Molecule:photosystem ii reaction center protein x; PDBTitle: crystal structure of i-substituted photosystem ii complex 10 c1s5lx_ 7.1 30 PDB header:photosynthesis Chain: X: PDB Molecule:photosystem ii psbx protein; PDBTitle: architecture of the photosynthetic oxygen evolving center 11 c3fseB_ 6.1 75 PDB header:hydrolase Chain: B: PDB Molecule:two-domain protein containing dj-1/thij/pfpi-like and PDBTitle: crystal structure of a two-domain protein containing dj-1/thij/pfpi-2 like and ferritin-like domains (ava_4496) from anabaena variabilis3 atcc 29413 at 1.90 a resolution 12 d1r7ma1 5.9 36 Fold:Homing endonuclease-like Superfamily:Homing endonucleases Family:Group I mobile intron endonuclease

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0