|   |
2 | . | . | . | . | . | . | . | 10 | |
. | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
30 | . | . | . | . | . | . | . | . | . | 40 | . | |
|
|
. | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
| . |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
| . | . | . | . | . |  |  |  |  |  |
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
T | I | Y | T | L | S | H | G | S | . |
L | K | L | D | V | S | D | Q | G | G | V | I | E | G | F | W | R | D | T | . |
. |
. |
. |
. |
T | P | L | L | R | P | G | K | K | S | G | V | . |
. |
. |
A | T | D | A | S | C | F | P | L | V | P | F | A | N | R | V | S | G | N | R | F | V | W | Q | G | R | E | Y | Q | L | Q |
Query Conservation |   |
  |   |   |   |
|   |   |   |   | . |   |   |   |   |
|   |   |   |
|
|   |
|   |
|   |   |   |   |
| . | . | . | . | . |   |   |   |
|   |   |   |   |   |   |   |   | . | . | . |   |   |   |   |   |   |   |   |
|   |
|   |   |
|
|   |   |   |
|   |   |   |   |   |
|   |   |   |   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |
|
|   |
|   |   |
|   |   |
|   |
|   |   |   |
|
|   |
|   |
|   |   |   |   |   |   |   |
|   |   |   |
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |
|   |   |
|
|
|   |   |
|   |
|   |   |   |
|   |   |
|   |
|   |
Template Sequence |   |
G | F | I | E | I | A | N | K | Q | G | L | T | A | T | L | L | P | F | G | A | T | L | A | K | L | T | F | P | D | K | N | G | K | N | Q | D | L | V | L | G | F | D | T | I | D | E | F | E | K | D | A | A | S | I | G | K | T | V | G | R | V | A | N | R | I | K | N | S | T | L | H | F | D | G | K | Q | Y | T | X | T |
Template Known Secondary structure |   |
|
|  |  |  |  |
| S | S | S |
|  |  |  |  |  | T | B | T | T |  |  |  |  |  |  |  |  |
| T | T | S |
|  |  |  |
| B |
|
|
| S | S |  |  |  |  |  |  |
| S | S |
| T | T |
|  |  |
| S | B |
| S |  |  | G | G | G |  |  |  |  | T | T |  |  |  |  |
|
|
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|  |  |
|
|  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
1004 | . | . | . | . | . | 1010 | . | . | . | . | . | . | . | . | . | 1020 | . | . | . | . | . | . | . | . | . | 1030 | . | . | . | . | . | . | . | . | . | 1040 | . | . | . | . | . | . | . | . | . | 1050 | . | . | . | . | . | . | . | . | . | 1060 | . | . | . | . | . | . | . | . | . | 1070 | . | . | . | . | . | . | . | . | . | 1080 | . | . | . |
  |
  |   |
73 | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | |
|
|
. | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | |
|
|
|
. | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
| . | . | . | . |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
P | N | V | E | W | D | A | H | Y | L | H | G | D | G | W | . |
. |
. |
L | G | E | W | Q | C | V | S | H | S | D | D | S | L | C | L | V | Y | E | H | . |
. |
. |
. |
R | S | G | V | Y | H | Y | R | V | S | Q | A | F | H | L | T | A | D | T | L | T | V | T | L | S | V | T | N | Q | G | A | E | T | L | P | F | G | T |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |
|
|   |   |   | . | . | . |   |   |   |
|   |
|   |   |   |   |   |   |   |
|   |
|   |   |   |   | . | . | . | . |   |   |   |
|   |   |   |   |
|   |   |   |
|   |
|   |   |   |   |
|   |
|   |   |   |
|   |
|   |
|   |   |   |   |
|   |   |   |
Alig confidence |   |
|
|
|
| . | . |
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |   | . | . |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |
|   |
|   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |
|
|   |
|   |   |   |   | . |   |
|   |
|   |   |   |
|   |   |   |   |   |   |
|   |   |   |
Template Sequence |   |
P | N | N | G | . |
. |
P | H | Y | L | H | G | G | P | N | G | L | G | Y | R | K | W | E | V | V | R | H | A | P | E | S | V | S | F | S | V | R | A | N | E | Q | D | D | G | L | P | G | D | A | K | I | D | V | T | Y | T | V | N | D | R | N | . |
Q | L | I | I | E | H | H | A | T | C | D | T | P | G | L | L | A | L |
Template Known Secondary structure |   |
| S | B | T | . | . | T | B |  |  | T | T |
| T | T | S | G | G | G | S | B |
|  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |  |  |  |  |  |  | S | S | S | S |  |  |  |  |  |  |  |  |  |  |
| T | T | S | . |  |  |  |  |  |  |  |  |  |
| S | S |
|  |  |
| B |
|
Template Predicted Secondary structure |   |
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
| . |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
1084 | . | . | . | |
|
. | . | 1090 | . | . | . | . | . | . | . | . | . | 1100 | . | . | . | . | . | . | . | . | . | 1110 | . | . | . | . | . | . | . | . | . | 1120 | . | . | . | . | . | . | . | . | . | 1130 | . | . | . | . | . | . | . | . | . | 1140 | . | . | |
. | . | . | . | . | . | . | 1150 | . | . | . | . | . | . | . | . | . | 1160 |
  |
  |   |
146 | . | . | . | 150 | . | . | . | . | . | |
|
|
|
|
. | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | |
. | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
. | . | 200 | . | . | . | |
|
|
|
. | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|  |  |
|
|
| . | . | . | . | . |
|
|  |  |  |  |  |
|
|  |  |  |  |  |
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |
|
|
|
| . | . | . | . | . | . | . | . |  |  |  |  |  |  | . | . | . | . |  |
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
Query Sequence |   |
G | W | H | P | Y | F | P | L | S | P | . |
. |
. |
. |
. |
Q | T | R | I | Q | A | Q | A | S | G | Y | W | L | E | R | E | Q | W | L | A | G | E | . |
F | C | E | Q | L | P | Q | E | L | D | F | N | Q | P | A | P | L | P | R | Q | . |
. |
. |
. |
. |
. |
. |
. |
W | V | N | N | G | F | . |
. |
. |
. |
A | G | W | N |
Query Conservation |   |
|   |
|
|
|
|   |   |   |   | . | . | . | . | . |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   | . | . | . | . | . | . | . | . |   |   |
|   |   |   | . | . | . | . |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
| . | . | . | . |
|
|
|
|
Template Conservation |   |
|   |
|
|
|
|   |
|   |   |   |   |   |
|   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |
|   |   |   |
|
|
|
|   |   |   |   |   |   |   |
|   |   |
|
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
T | N | H | A | Y | W | N | L | D | G | S | D | T | V | A | E | H | F | L | E | X | E | A | D | E | F | V | E | V | D | D | T | F | C | P | T | G | A | I | R | S | V | T | D | T | G | F | D | F | R | S | G | K | Q | L | K | E | S | G | K | D | A | E | E | L | L | D | L | D | N | D | L | V | I | T | K | K | T | P | S |
Template Known Secondary structure |   |
 |  |
|
|  |  |
| S | S |
|
| S |
| S | T | T |
|  |  |  |  |
|  |  |  |  |  |  |  |
| T | T | S |
|  |  |  |  |  |  |  |
| T | T | S | T | T |
|
| T | T |
|  |  | T | T |
| S |
|
|
| S | S |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
1161 | . | . | . | . | . | . | . | . | 1170 | . | . | . | . | . | . | . | . | . | 1180 | . | . | . | . | . | . | . | . | . | 1190 | . | . | . | . | . | . | . | . | . | 1200 | . | . | . | . | . | . | . | . | . | 1210 | . | . | . | . | . | . | . | . | . | 1220 | . | . | . | . | . | . | . | . | . | 1230 | . | . | . | . | . | . | . | . | . | 1240 |
  |
  |   |
208 | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | |
|
|
|
|
|
. | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . |
Predicted Secondary structure |   |
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | Q | A | R | I | E | Q | P | Q | E | G | Y | A | I | I | M | E | T | T | P | P | A | P | C | Y | F | I | F | V | S | D | P | A | F | . |
. |
. |
. |
. |
. |
D | K | G | Y | A | F | D | F | F | C | L | E | P | M | S | H | A | P | D | D | H | H | R | P | E | G | G | D | L | I | A | L | A | P | G | E | S | T | T | S |
Query Conservation |   |
  |   |   |   |
|   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   | . | . | . | . | . | . |   |   |   |   |   |   |   |   |
|
|
|
|
|   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|
|   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |
|   |   |   |   |   |
|   |   |
|   |
|   |
| . | . |   |   |
|   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|   |   |   | . |
|
|
|   |
|   |   |   |   |   |   | . |   |   |
|   |
|
|
|   |   |   |   |
Template Sequence |   |
T | Y | L | R | F | W | S | E | K | S | G | I | E | L | S | I | T | T | . |
. |
S | Y | P | V | I | H | L | Y | A | S | K | F | L | D | C | K | G | K | K | G | E | H | Y | K | A | N | K | A | L | A | I | E | P | Q | F | H | . |
S | A | A | P | N | F | D | H | F | P | D | . |
V | S | L | R | P | G | D | H | Y | C | Q |
Template Known Secondary structure |   |
|
|  |  |  |  |
| T | T | T |
|  |  |  |  |  |  |  | . | . | S | S | S |  |  |  |  |  |
|
| T | T |
|
|  |  |
| G | G | G |
|  |  |
| T | T |
|
|  |  |  |  |  |  | S |
| . | T | T | G | G | G |
| T | T | S |
|
| . |
|  |  |
| T | T |
|
|  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
| . | . |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
| . |  |  |  |
|
|
|
|  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
1245 | . | . | . | . | 1250 | . | . | . | . | . | . | . | . | . | 1260 | . | . | |
|
. | . | . | . | . | . | . | 1270 | . | . | . | . | . | . | . | . | . | 1280 | . | . | . | . | . | . | . | . | . | 1290 | . | . | . | . | . | . | . | . | |
. | 1300 | . | . | . | . | . | . | . | . | . | |
1310 | . | . | . | . | . | . | . | . | . | 1320 |
  |
  |   |
282 | . | . | . | . | . | . | . | 290 |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | M | S | L | R | V | E | W | L |
Query Conservation |   |
  |   |   |
|   |
|   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |
|   |
|   |   |   |
Template Sequence |   |
E | I | V | Y | T | F | S | H | V |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |
|
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
  |   |
1321 | . | . | . | . | . | . | . | . |
  |