|   |
22 | . | . | . | . | |
|
|
. | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | |
|
|
|
|
. | . | . | . | 50 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | 60 | . | . | |
. | . | . | . | . | . | . | 70 | . | . | . | . | |
|
Predicted Secondary structure |   |
|
|
|
|
| . | . | . |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  | . | . | . | . | . |  |
|
|
|
|
|
|
|
|  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  | . |  |  |
|
|
|
|  |  |  |  |  |
| . | . |
Query SS confidence |   |
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
Query Sequence |   |
T | A | Y | P | D | . |
. |
. |
P | V | Q | A | A | F | I | A | E | Q | A | G | A | D | G | I | T | V | H | . |
. |
. |
. |
. |
L | R | E | D | R | R | H | I | T | D | R | D | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
V | R | I | L | R | . |
Q | T | L | D | T | R | M | N | L | E | M | A | . |
. |
Query Conservation |   |
  |   |   |
|
| . | . | . |   |
|   |
|
|   |   |
|   |   |
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|   |
|   |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|   |   |
|   | . |   |   |   |   |   |   |   |
|
|
|   |   | . | . |
Alig confidence |   |
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
| . | . |
Template Conservation |   |
|
|   |
|
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
|
|   |
|
|
|
|
|
|
|
|
|
|   |
|
|
|
|
|
|
|   |
|   |   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |
|
|
|
|
|   |
|   |
|
Template Sequence |   |
I | G | D | P | N | P | E | Q | S | L | A | I | M | Q | T | L | I | D | A | G | A | D | A | L | E | L | G | M | P | F | S | D | P | L | A | D | G | P | T | I | Q | G | A | N | L | R | A | L | A | A | K | T | T | P | D | I | C | F | E | L | I | A | Q | I | R | A | R | N | P | E | T | P | I | G | L | L | M | Y | A | N |
Template Known Secondary structure |   |
T | T | S | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
| S | S |  |  |  |  |
|
|
|
|
| T | T |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| T | T | S |
|  |  |  |  |  |
|  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
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|
|
|
|
|
|
|
|
|
|
|
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|
|
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|
|
  |   |
25 | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . |
  |
  |   |
|
|
|
|
|
75 | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | |
|
. | . | 140 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
. | . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
| . | . |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
. |
. |
V | T | E | E | M | L | A | I | A | V | E | T | K | P | H | F | C | C | L | V | P | E | K | R | Q | E | V | T | T | E | G | G | L | D | V | A | G | Q | R | D | K | M | R | D | A | C | K | R | L | A | D | A | G | I | Q | V | S | L | F | I | D | A | D | . |
. |
E | E | Q | I | K | A | A | A | E | V |
Query Conservation |   |
. | . | . | . | . |   |
|   |
|   |
|   |   |
|   |   |   |
|
|   |   |
|
|
|
|
|
|   |
|   |
|   |
|
|
|
|
|
|
|   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |   |   |
|
|
|
|
|
|
|
|
|
|   | . | . |   |   |   |
|   |   |
|   |   |   |
Alig confidence |   |
. | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |   |   |
|   |
|   |
|   |   |   |   |   |   |   |
|
|   |
|
|
|
| . |
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |
|
|   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |
|
|   |
|
|
|   |   |   |
|
|   |   |
|   |   |   |
Template Sequence |   |
L | V | Y | A | R | G | I | D | D | F | Y | Q | R | C | Q | K | A | G | V | D | S | V | L | I | . |
A | D | V | P | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
T | N | E | S | Q | P | F | V | A | A | A | E | K | F | G | I | Q | P | I | F | I | A | P | P | T | A | S | D | E | T | L | R | A | V | A | Q | L |
Template Known Secondary structure |   |
 |  |  | T | T |
|  |  |  |  |  |  |  |  |  |  |  | T |
|
|  |  |  |  | . | T | T | S |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | G | G | G |
|  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |
|  |  |
| T | T |
|
| S |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
| . |
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
105 | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | |
. | 130 | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . |
  |
  |   |
148 | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | |
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
Query Sequence |   |
G | A | P | F | I | E | I | H | T | G | C | Y | A | D | A | K | T | D | A | E | Q | A | Q | E | L | A | R | I | A | K | A | A | T | F | A | A | S | L | G | L | K | V | N | A | G | H | G | L | T | Y | H | N | V | K | A | I | A | A | I | P | E | M | H | E | L | N | I | G | H | A | I | I | G | R | A | V | M | T | G | . |
Query Conservation |   |
|
|
|   |
|
|
|
|
|
|   |
|
|   |
|   |   |   |   |   |   |   |   |
|
|   |   |
|   |   |
|
|   |   |
|   |   |
|
|
|   |
|
|
|
|
|
|
|   |
|   |
|
|   |   |
|
|   |
|   |   |
|   |
|
|
|
|
|
|
|
|
|
|   |
|
|   |   |
| . |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
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|
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|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
Template Conservation |   |
|   |
|
|
|
|   |
|
|   | . | . | . | . | . | . | . | . |   |
|
|
|   |   |
|   |   |
|
|   |   |
| . | . | . | . | . | . |   |   |
|
|   |
|
|
|
|
|   |   |
|
|   |   |   |   |   |   |   |   |
|
|
|
|
|
|
|
|
|
|
|
|   |   |
|   |   |   |   |   |
Template Sequence |   |
G | K | G | Y | T | Y | L | L | S | R | . |
. |
. |
. |
. |
. |
. |
. |
A | P | V | H | A | L | L | E | R | L | Q | Q | F | D | . |
. |
. |
. |
. |
. |
A | P | P | A | L | L | G | F | G | I | S | E | P | A | Q | V | K | Q | A | I | E | A | G | A | A | G | A | I | S | G | S | A | V | V | K | I | I | E | T | H | L | D |
Template Known Secondary structure |   |
|
| S |
|  |  |  |
|
|
| . | . | . | . | . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |  | T | T | . | . | . | . | . | . |
|
|
|  |  |  |
| S | S |
|
| S |  |  |  |  |  |  |  |  |  | T | T |
| S |  |  |  |  | S | S |  |  |  |  |  |  |  |  | T | T | T |
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |
| . | . | . | . | . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |
|
| . | . | . | . | . | . |
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|  |  |  |  |  |  |  |  |  |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
170 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | |
|
|
|
|
|
. | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . |
  |
  |   |
|
|
|
|
227 | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . |
Predicted Secondary structure |   |
. | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Query SS confidence |   |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
. |
L | K | D | A | V | A | E | M | K | R | L | M | L | E | A |
Query Conservation |   |
. | . | . | . |
|   |   |
|
|   |   |
|   |   |   |
|   |   |
|
Alig confidence |   |
. | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|
|   |
|
Template Sequence |   |
N | P | A | K | Q | L | T | E | L | A | N | F | T | Q | A | M | K | K | A |
Template Known Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
247 | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . |
  |