|   |
118 | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
F | V | K | D | E | I | G | F | S | Y | N | G | Y | Y | R | S | G | W | G | T | A | S | H | G | S | P | K | S | W | A | I | G | S | L | G | R | F | G | N | E | Y | S | G | W | F | D | L | Q | L | K | Q | R | V | Y | N | E | N | G | K | R | V | D | A | V | V | M | M | D | G | N | V | G | Q | Q | Y | S | T | G | W | F |
Query Conservation |   |
  |
|   |   |   |   |
|
|
|
|
|
|
|   |
|
|
|   |
|   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |
|
|
|
|
|
|   |
|
|
|   |
|
|   |
|   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |
|   |   |   |
|   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
Template Conservation |   |
|   |   |
|
|
|   |
|   |
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |
|
|
|
|   |   |
|   |   |   |
|   |   |
|
|   |
|   |   |   |
|
|   |   |   | . | . | . | . | . | . | . | . |   |   |   |
Template Sequence |   |
Y | N | K | D | G | N | K | L | D | L | Y | G | K | A | V | G | R | H | V | W | T | T | T | G | D | S | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
K | N | A | D | Q | T | Y | A | Q | I | G | F | K | G | E | T | Q | I | N | T | D | L | T | G | F | G | Q | W | E | Y | R | T | . |
. |
. |
. |
. |
. |
. |
. |
K | A | D |
Template Known Secondary structure |   |
|
|
| T | T |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
| S | T | T |
| . | . | . | . | . | . | . | . | . | . | . |
|
|  |  |
|
|  |  |  |  |  |  |  |  |  |  |
| S | S | S | S |
|  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . |  |
| S |
Template Predicted Secondary structure |   |
 |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
4 | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | |
|
|
|
|
|
|
|
. | . | . |
  |
  |   |
198 | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | |
240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
| . |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | D | N | A | G | G | E | N | Y | M | Q | F | S | D | M | Y | V | T | T | K | G | F | L | P | F | A | P | E | A | D | F | W | V | G | K | H | G | A | P | K | I | E | . |
I | Q | M | L | D | W | K | T | Q | R | T | D | A | A | A | G | V | G | L | E | N | W | K | V | G | P | G | K | I | D | I | A | L | V | R | E | D |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|   |   |   |   |   |   |   |   |   |
|   |
|
|
|
|
|
|
|
|
|
|   |
|   |
| . |
|
|
|   |
|   |   |   |   |   |   |   |
|
|   |
|
|
|
|
|
|
|   |
|
|   |
|
|
|   |   |
|   |   |   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|
| . | . | . | . |
|   |   |   |   |   |
|   |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
Template Sequence |   |
R | A | E | G | E | Q | Q | N | S | N | L | V | R | L | A | F | A | G | . |
. |
. |
. |
L | K | Y | A | E | V | G | S | I | D | Y | G | R | N | Y | G | I | V | Y | D | V | E | S | Y | T | D | X | A | P | Y | F | S | . |
G | E | T | W | G | G | A | Y | T | D | N | Y | X | T | S | R | A | G | G | L | L | T | Y | R | N |
Template Known Secondary structure |   |
S |
| T | T |
|
| S | T | T |  |  |  |  |  |  |  |  |  | . | . | . | . |  |  |  | T | T | T |  |  |  |  |  |  |  |  |  |
| T | T |  |  |  |  |  | T | T |
|
| S | S | S | S | S | . | S |
| S | T | T | T | S | S | S | S | S | T | T | S | S |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  | . | . | . | . |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
65 | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | |
|
|
|
. | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | |
. | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . |
  |
  |   |
277 | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | |
|
|
|
|
|
|
|
. | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | D | D | Y | D | R | S | L | Q | N | K | Q | Q | I | N | T | N | T | I | D | L | R | Y | K | D | I | P | L | W | D | K | A | T | L | M | V | S | G | R | Y | V | T | A | N | E | S | A | S | . |
. |
. |
. |
. |
. |
. |
. |
E | K | D | N | Q | D | N | N | G | Y | Y | D | W | K | D | T | W | M | F | G | T | S | L | T |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |
|   |   |   |   |   |   |   |
|   |
|   |   |   |
|   |   |   |
|   |   |   |   | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
Template Sequence |   |
S | D | F | F | G | L | V | D | G | L | S | F | G | I | Q | Y | Q | G | K | N | Q | D | N | H | S | I | N | S | Q | N | G | D | G | V | G | Y | T | X | A | Y | E | F | D | G | F | G | V | T | A | A | Y | S | N | S | K | R | T | N | D | Q | Q | D | R | D | G | N | G | D | R | A | E | S | R | A | V | G | A | K | Y | D |
Template Known Secondary structure |   |
S | S | S | S | S | S |
| S | S |  |  |  |  |  |  |  |  |
|
| B |
| S | S | S |
| G | G | G |
| B |
| S |  |  |  |  |  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |  |  |  |
|
|
| S | T | T | S | S | S | S | S |
|
| S |
|  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . |
  |
  |   |
349 | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Q | K | F | D | K | G | G | F | N | E | F | S | F | L | V | A | N | N | S | I | A | S | N | F | G | R | Y | A | G | A | S | P | F | T | T | F | N | G | R | Y | Y | G | D | H | T | G | G | T | A | V | R | L | T | S | Q | G | E | A | Y | I | G | D | H | F | I | V | A | N | A | I | V | Y | S | F | G | N | D | I | Y | S |
Query Conservation |   |
  |   |   |   |   |
|
|
|
|
|   |   |   |
|
|
|   |   |   |   |
|   |   |   |
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|
|   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |
|   |   |   |
Alig confidence |   |
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
Template Conservation |   |
  |   |   |   |   | . | . | . | . | . |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   | . | . |
Template Sequence |   |
A | N | N | V | Y | . |
. |
. |
. |
. |
L | A | A | V | Y | A | E | T | R | N | X | S | I | V | E | N | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
T | V | T | D | T | V | E | X | A | N | K | T | Q | N | L | E | V | V | A | Q | Y | Q | F | D | F | G | L | R | P | A | I | S | Y | V | Q | S | K | G | K | Q | L | . |
. |
Template Known Secondary structure |   |
 | T | T |  |  | . | . | . | . | . |  |  |  |  |  |  |  |  | S | S |
|
|
|  |  |
| . | . | . | . | . | . | . | . | . | . | . | T | T | T |
|
|  |  |
|
| S |  |  |  |  |  |  |  |  |  |  |  |
|
| T | T | S |
|
|  |  |  |  |  |  |  |  |  |  |  | S |
| . | . |
Template Predicted Secondary structure |   |
|
|
|  |  | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
220 | . | . | . | . | |
|
|
|
|
. | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | |
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | |
|
  |
  |   |
429 | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Y | E | T | G | A | H | S | D | F | E | S | I | R | A | V | V | R | P | A | Y | I | W | D | Q | Y | N | Q | T | G | V | E | L | G | Y | F | T | Q | Q | N | K | D | A | N | S | N | K | F | N | E | S |
Query Conservation |   |
  |   |   |   |   |   |   |
|   |   |   |   |
|   |   |
|
|
|   |
|   |   |
|   |   |   |   |   |   |   |
|   |
|
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
Alig confidence |   |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|   |   |   |   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
. |
N | G | A | G | G | S | A | D | L | A | K | Y | I | Q | A | G | A | T | Y | Y | F | N | K | N | X | N | V | W | V | D | Y | R | F | N | L | L | D | E | N | D | Y | S | S | S | Y | V | G | T | D |
Template Known Secondary structure |   |
. | T | T | T | T | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| S | S |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
| S | S |
| T | T | T | T |
| S | S |
Template Predicted Secondary structure |   |
. |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
282 | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 |
  |