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Job DescriptionP76578
Confidence100.00%DateWed Jan 25 15:21:09 GMT 2012
Rank6Aligned Residues877
% Identity18%Templatec3pvmB_
PDB info PDB header:immune systemChain: B: PDB Molecule:cobra venom factor; PDBTitle: structure of complement c5 in complex with cvf
Resolution4.30 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   388.390.........400.........410.........420.........430.........440.........450.........460.......
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Query Sequence  FFMFGPRDLYRPGETVILNGLLRDADGKALPNQPIKLDVIKPDGQVLRSVVSQPENGLYHFTWPLDSNAATGMWHIRANT
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Template Sequence  LFIQTDKGIYTPGSPVLYRVFSMDHNTSKMNK. TVIVEFQTPEGILVSSNSVD. . . LNFFWPYNLPDLVSLGTWRIVAKY
Template Known Secondary structure  S
S
TT





S



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TTS

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SS


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   128.130.........140.........150......... 160.........170......... 180.........190.........200...
 
   468.470 .........480.........490.........500 .........510.........520 .........530.........540...
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Query Sequence  GDN. QYRMWDFHVEDFMPERMALNLTGEKTPLTP. . KDEVKFSVVGYYLYGAPANG. NTLQGQLFLRPLREAVSALPGFE
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Template Sequence  EHSPENYTAYFDVRKYVLPSFEVRLQPSEKFFYIDGNENFHVSITARYLYGEEVEGVAFVLFGVKIDDAKKSIPDSL. . .
Template Known Secondary structure  TT





SSSSTT



TTT

TT
GGG
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   204.....210.........220.........230.........240.........250.........260.........270.........280
 
   544.....550.........560.........570.... .....580.........590....... ..600.........610......
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Query Sequence  FGDIAAENLSRTLDEVQLTLDDKGRGEVSTE. . . . . SQWKETHSPLQVIFQGSLLESGG. . RPVTRRAEQAIWPADALPG
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Template Sequence  . . . . . . . . . . . . . . TRIPIIDGDGKATLKRDTFRSRFPNLNELVGHTLYASVTVMTESGSDMVVTEQSGIHIVASPYQIH
Template Known Secondary structure  ..............BTT



TTTTSS
S
S
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   281........290.........300.........310.........320.........330.........340......
 
   617..620.........630.........640.........650.........660.........670.........680.........690......
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Query Sequence  IRPQFASKSVYDYRTDSTVKQPIVDEGSNAAFDIVYSDAQGVKKAVSGLQVRLIRERRDYYWNWSEDEGWQSQFDQKDLI
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Template Sequence  FTKT. . . . . . . . . . . . . . . . PKYFKPGMPYELTVYVTNPDGSPAAHVPVVS. . . . . . . . . . . . . . . . . . . . . . . . . . EAF
Template Known Secondary structure 
SSS................
S
TTS
TTS
B

S
..........................GGG
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   347..350 .........360.........370.........380. ...
 
   697..700.........710.........720.........730.........740.........750.........760.........770......
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Query Sequence  ENEQTLDLKADETGKVSFPVEWGAYRLEVKAPNEAVSSVRFWAGYSWQDNSDGSGAVRPDRVTLKLDKASYRPGDTIKLH
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Template Sequence  HSMGTTLSDGTAKLILNIPLNAQSLPITVRTNHGDLPRER. QATKSMTAIAYQTQGGSGNYLHVAITSTEIKPGDNLPVN
Template Known Secondary structure  T

TTS

TT




TTS
TTT.S



GGG





SB
TT
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   385....390.........400.........410.........420.... .....430.........440.........450.........460...
 
   777..780.... .....790.........800........ .810.........820.........830.........840.......
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Query Sequence  IAAPTAGK. . . . . . . GYAMVESSEGPLWWQEIDVRAQGL. . DLTIPVDKTWNRHDLYLSTLVVRPGDKSRSATPKRAVGV
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Template Sequence  FNVKGNANSLKQIKYFTYLILNKGKIFKVGRQPRRDGQNLVTMNLHITPDL. IPSFRFVAYYQVGNNE. . . . . . . IVADS
Template Known Secondary structure  S
TT

TT

TT
S

GGG.TTTTT.......
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   464.....470.........480.........490.........500.........510.... .....520.........530 .....
 
   848.850..... ....860.........870.........880.........890.........900.........910.........920.....
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Query Sequence  LHLPLGDE. NRRLDLALETPAKMRPNQPLTVKIKASTKNGEKPKQVNVLVSAVDSGVLNITDYVTPDPWQAFFGQKRYG.
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Template Sequence  VWVDVKDTCMGTLVVKGD. NLIQMPGAAMKIKLEGDP. . . . . . . GARVGLVAVDKAVYVLNDKYKISQAKIWDTIEKSDF
Template Known Secondary structure  B



SS


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B
TT

T.......T
TTTTS

TT

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   536...540.........550... ......560.........570. ........580.........590.........600.......
 
   926...930.........940.........950.........960.........970......... 980..
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Query Sequence  . . . . . . . . . . . . . . . . . . ADIYDIYGQVIEGQGRLAALRFGGDGDELKRGGKPPVNHVNIVVQQALPVTLNE. . . . . QGE
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Template Sequence  GCTAGSGQNNLGVFEDAGLALTTSTNLNTKQRSAAKCPQPANEDGFIADSDIISRSDFPKSWLWLTKDLTEEPNSQGISS
Template Known Secondary structure 

SSB

SS
TTS
B





SS

S


TTSS

GGG


B



S

S


TTS
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   608.610.........620.........630.........640.........650.........660.........670.........680.......
 
   983......990.........1000...... ...1010... ......1020.........1030.........1040.........1050.........1060
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Query Sequence  GSVTLPIGDFNGELRVMAQAWTAD. DFGSNES. KVIVAAPVIAELNMPRFMASGDTSRLTLDITNLTDKPQKLNVALTAS
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Template Sequence  KTMSFYLRDSITTWVVLAVSFTPTKGICVAEPYEIRVMKVFFIDLQMPYSVVKNEQVEIRAILHNYVNEDIYVRVELLYN
Template Known Secondary structure 

S
SSBTTTB

B


B

S



S
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SSS



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   774.....780.........790.........800.........810.........820.........830.........840.........850...
 
   1061........1070 .........1080.........1090.........1100.........1110.........1120.........1130......
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Query Sequence  GLLELVSDSP. . . . AAVELAPGVRTTLFIPVRALPGYGDGEIQATISGLALPGETVADQHKQWKIGVRPAFPAQTVNYGT
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Template Sequence  PAFCSASTKGQRYRQQFPIKALSSRAVPFVIVPLE. QGLHDVEIKASV. . . . QEALWSDGVRKKLKVVPEGVQKSIVTIV
Template Known Secondary structure  TTS

SSS


SS
S.
....SSSS

SS
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   854.....860.........870.........880........ .890.........900 .........910.........920........
 
   1137..1140 .........1150........ .1160.........1170.........1180.........1190.........1200........
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Query Sequence  ALQP. . . . . . . GETWAIPADGLQNFSPVT. LEGQLLLSGKPPLNIARYIKELKAYPYGCLEQTASGLFPSLYTNAAQLQA
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Template Sequence  KLDPRAKGVGGTQLEVIKARKLDDRVPDTEIETKIIIQGDPHKD. . . . . LNLDITIELPDREVPIRYRI. . . . . . . . . . .
Template Known Secondary structure 
TTTT
SSS





SS
TT





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TT
SS
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   929930.........940.........950.........960.........970.. .......980.........990..
 
   12091210.........1220.........1230. ........1240.........1250.........1260.........1270.........1280......
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Query Sequence  LGIKGDSDEKRRASVDIGISRLL. . QMQRDNGGFALWDKNGDEEYWLTAYVMDFLVRAGEQGYSVPTDAINRGNERLLRY
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Template Sequence  . . . . . . . . . . . . NYENALLARTVETKLNQDITVTASG. DGKATMTILTFYNAQLVCNKFHL. . . . . . . . . . . . . . . . . . .
Template Known Secondary structure  ............
TTTSS

SS


.SS




S
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   1293......1300.........1310....... ..1320.........1330.........1340
 
   1287..1290.........1300.........1310.........1320.........1330.........1340.........1350.........1360......
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Query Sequence  LQDPGMMSIPYADNLKASKFAVQSYAALVLARQQKAPLGALREIWEHRADAASGLPLLQLGVALKTMGDATRGEEAIALA
Query Conservation      
                  
     
             
             
  
 

               
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Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Template Known Secondary structure  ................................................................................
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   1367..1370.........1380.........1390.........1400.........1410.........1420.........1430.........1440......
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Query Sequence  LKTPRNSDERIWLGDYGSSLRDNALMLSLLEENKLLPDEQYTLLNTLSQQAFGERWLSTQESNALFLAARTIQDLPGKWQ
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Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Template Known Secondary structure  ................................................................................
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   1447..1450.........1460.........1470.........1480.........1490.........1500.........1510.........1520......
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Query Sequence  AQTSFSAEQLTGEKAQNSNLNSDQLVTLQVSNSGDQPLWLRMDASGYPQSAPLPANNVLQIERHILGTDGKSKSLDSLRS
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Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . NVSVENIHLNKGALMLKICTRYLGEVDS. . . . . . . . . . . . . . . . . . . . . . . . . . . .
Template Known Secondary structure  ........................







SSS
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   1346...1350.........1360.........1370...
 
   1527..1530.........1540.........1550 .........1560.........1570.........1580.........1590....... ..1600
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Query Sequence  GDLVLVWLQVKASNSVPDALVVDL. LPAGLELENQNLANGSASLEQSGGEVQNLLNQMQQASIKHIEFRDDR. . . . . FVA
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Template Sequence  . . . . . . . . . . . . . . . . . TMTIIDISMLTGFLPDAEDLTRLSKG. . . . . . . . . . . . . . . VDRYISRYEVDNNMAQKVAVII
Template Known Secondary structure  .................

TTB
S...............SS




TTS
S
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   1378.1380.........1390.........1400... ......1410.........1420.....
 
   1601........ 1610.........1620........ .1630.........1640.
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Query Sequence  AVAVDEYQP. VTLVYLARAVTPGTYQVPQ. PMVESMYVPQWRA
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Template Conservation   
         
  
       

  

    

 

 
   
Template Sequence  YLNKVSHSEDECLHFKILKHFEVGFIQPGSVKVYSYYNLDEKC
Template Known Secondary structure 
SSS
S


S



TTBTT


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   1426...1430.........1440.........1450.........1460........
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
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