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Job DescriptionP76578
Confidence100.00%DateWed Jan 25 15:21:09 GMT 2012
Rank12Aligned Residues549
% Identity14%Templatec2qkiA_
PDB info PDB header:immune system/hydrolase inhibitorChain: A: PDB Molecule:complement c3; PDBTitle: human c3c in complex with the inhibitor compstatin
Resolution2.40 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   296...300.........310.........320.........330.........340.........350.........360.........370.....
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Query Sequence  AHRYHNRLDIFTQSLENGAAQQGIEVSLLNEKGQTLTQATSDAQGHVQLENDKNAALLLARKDGQTTLLDLKLPALDLAE
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Template Sequence  ILRLESEETMVLEAHDAQGDVP. VTVTVHDFPGKKLVLSSEKTVLTPATNHMGNVTFTIPANRGRNKFVTVQATFGTQVV
Template Known Secondary structure  BTSS

S
.SSS


BS



TTTTSB






TT
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   11........20.........30.. .......40.........50.........60.........70.........80.........
 
   376...380.........390.........400.........410.........420.........430.........440 .........450...
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Query Sequence  FNIAGAPGYSKQFFMFGPRDLYRPGETVILNGLLRDADGKALPNQPIKLDVIKPDGQVLRSVVSQ. . PENGLYHFTWPLD
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Template Sequence  EKVVLVSLQSGYLFIQTDKTIYTPGSTVLYRIFTVNHKLLP. VGRTVMVNIENPEGIPVKQDSLSSQNQLGVLPLSWDIP
Template Known Secondary structure 



S
S
TT

TTS
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TT


TTTTT

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   96...100.........110.........120.........130...... ...140.........150.........160.........170....
 
   454.....460.........470. ........480.........490..... ....500.........510.........520.........
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Query Sequence  SNAATGMWHIRANTGDNQ. . YRMWDFHVEDFMPERMALNLTGEK. . TPLTPKDEVKFSVVGYYLYGAPANGNTLQGQLFL
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Template Sequence  ELVNMGQWKIRAYYENSPQQVFSTEFEVKEYVLPSFEVIVEPTEKFYYIYNEKGLEVTITARFLYGKKVEGTAF. . . . . .
Template Known Secondary structure  SS


TT
TTS






SSSSSTT
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B

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   175....180.........190.........200.........210.........220.........230.........240........
 
   530.........540.........550.........560.........570.... .....580.........590..... ....600
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Query Sequence  RPLREAVSALPGFEFGDIAAENLSRTLDEVQLTLDDKGRGEVSTE. . . . . . . SQWKETHSPLQVIFQGSLLES. . GGRPV
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Template Conservation  ............
                        
                           
 
 
          
Template Sequence  . . . . . . . . . . . . VIFGIQDGEQRISLPESLKRIPIEDGSGEVVLSRKVLLDGVQRAEDLVGKSLYVSATVILHSGSDMVQ
Template Known Secondary structure  ............SSS

GGG
BTT
TT


GGGTT
TTSS
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   249250.........260.........270.........280.........290.........300.........310......
 
   601........610.........620.........630.........640.........650.........660.........670.........680
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Query Sequence  TRRAEQAIWPADALPGIRPQFASKSVYDYRTDSTVKQPIVDEGSNAAFDIVYSDAQGVKKAVSGLQVRLIRERRDYYWNW
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Template Sequence  AERSGIPIVTSPYQIHF. . . . . . . . . . . . . . . . TKTPKYFKPGMPFDLMVFVTNPDGSPAYRVPVAV. . . . . . . . . . . . .
Template Known Secondary structure  S
S

................TTS
S
TTS
TTS
B

S
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   319320.........330..... ....340.........350.........360.........
 
   681........690.........700.........710.........720.........730.........740.........750.........760
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Query Sequence  SEDEGWQSQFDQKDLIENEQTLDLKADETGKVSFPVEWGAYRLEVKAPNEAVSSVRFWAGYSWQDNSDGSGAVRPDRVTL
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Template Sequence  . . . . . . . . . . . . QGEDTVQSLTQGDGVAKLSINTHPSQKPLSITVRTKKQELSEAE. QATRTMQALPYSTVGNSNNYLHL
Template Known Secondary structure  ............SSSGGG


TTS

S

S


TTS
TTT.S



TTS


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   370.........380.........390.........400.........410... ......420.........430......
 
   761........770.........780..... ....790.........800.... .....810.........820.........830.
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Query Sequence  KLDKASYRPGDTIKLHIAAPTAGKG. . . . . . . YAMVESSEGPLWWQEIDVR. . AQGLDLTIPVDKTWNRHDLYLSTLVVR
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Template Sequence  SVLRTELRPGETLNVNFLLRMDRAHEAKIRYYTYLIMNKGRLLKAGRQVREPGQDLVVLPLSITTDF. IPSFRLVAYYTL
Template Known Secondary structure 


S


TT

TTTGGG

TT

TT
S
GGG.
S
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   437..440.........450.........460.........470.........480.........490.........500... ......510.....
 
   832.......840.........850..... ....860.........870.........880.........890.........900.........910
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Query Sequence  PGDKSRSATPKRAVGVLHLPLGDE. NRRLDLALETPAKMRPNQPLTVKIKASTKNGEKPKQVNVLVSAVDSGVLNITDYV
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Template Sequence  IGASGQR. . . EVVADSVWVDVKDSCVGSLVVKSG. QSQPVPGQQMTLKIEGDH. . . . . . . GARVVLVAVDKGVFVLNKKN
Template Known Secondary structure 
SSS
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SS
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TT




T.......T








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   516...520.. .......530.........540...... ...550.........560.... .....570.........580....
 
   911.......
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Query Sequence  TPDPWQAF
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Template Conservation   

   
 
Template Sequence  KLTQSKIW
Template Known Secondary structure 


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   588.590.....
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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