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Job DescriptionP76578
Confidence100.00%DateWed Jan 25 15:21:09 GMT 2012
Rank4Aligned Residues665
% Identity15%Templatec2a73B_
PDB info PDB header:immune systemChain: B: PDB Molecule:complement c3; PDBTitle: human complement component c3
Resolution3.30 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   950.........960.........970.........980 .........990.........1000...... ...1010.. .......1020...
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Query Sequence  DGDELKRGGKPPVNHVNIVVQQALPVTLNEQ. . . . GEGSVTLPIGDFNGELRVMAQAWTAD. DFGSNE. SKVIVAAPVIA
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Template Sequence  DEDIIAEENIVSRSEFPESWLWNVEDLKEPPKNGISTKLMNIFLKDSITTWEILAVSMSDKKGICVADPFEVTVMQDFFI
Template Known Secondary structure 






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S



TTT




S
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   730.........740.........750.........760.........770.........780.........790.........800.........
 
   1024.....1030.........1040....... ..1050.........1060.........1070 .........1080.........1090........
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Query Sequence  ELNMPRFMASGDTSRLTLDITNLT. DKPQKLNVALTASGLLELVSDSP. . . . AAVELAPGVRTTLFIPVRALPGYGDGEI
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Template Sequence  DLRLPYSVVRNEQVEIRAVLYNYRQNQELKVRVELLHNPAFCSLATTKRRHQQTVTIPPKSSLSVPYVIVPLK. TGLQEV
Template Known Secondary structure 

STT


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TT
S

SSS

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   810.........820.........830.........840.........850.........860.........870.........880.. ......
 
   10991100.........1110.........1120.........1130........ .1140.........1150......... 1160.........
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Query Sequence  QATISGLALPGETVADQHKQWKIGVRPAFPAQTVNYGTAL. . . . . . . . QPGETWAIPADGLQNFSPVTL. EGQLLLSGKP
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Template Sequence  EVKAAV. . . . YHHFISDGVRKSLKVVPEGIRMNKTVAVRTLDPERLGREGVQKEDIPPADLSDQVPDTESETRILLQGTP
Template Known Secondary structure  ....SSS


SS


TBTTTBSS






TTB
TT


SSS
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   889890.... .....900.........910.........920.........930.........940.........950.........960....
 
   1170...... ...1180.........1190.........1200.........1210... ......1220.........1230.........1240
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Query Sequence  PLNIARY. . . . . . IKELKAYPYGCLEQTASGLFPSLYTNAAQLQALGIKG. . . DSDEKRRASVDIGISRLLQMQRDNGGF
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Template Sequence  VAQMTEDAVDAERLKHLIVTPSGCGEQNMIGMTPTVIAVHYLDETEQWEKFGLEKRQGALELIKKGYTQQLAFRQPSSAF
Template Known Secondary structure  SS
TTTGGGG
SS


STTGGGGGTTT

TTTS

TTT

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   965....970.........980.........990.........1000.........1010.........1020.........1030.........1040....
 
   1241........1250.........1260.........1270.........1280.... .....1290.........1300.... .....1310.....
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Query Sequence  ALWDKNGDEEYWLTAYVMDFLVRAGEQGYSVPTDAINRGNERLL. RYLQDPGMMSIPYADNLKAS. . . . KFAVQSYAALV
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Template Sequence  AAF. VKRAPSTWLTAYVVKVFSLAVNL. IAIDSQVLCGAVKWLILEKQKPDGVFQEDAPVIHQENNNEKDMALTAFVLIS
Template Known Secondary structure  BSS.SSS
B
TTTTT.S


B
TTS
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SS



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   1045.. ..1050.........1060.........1070 .........1080.........1090.........1100.........1110.........1120..
 
   1316...1320.. .......1330.........1340.........1350.........1360.........1370.........1380....
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Query Sequence  LARQQKA. . . . . . . . . . . PLGALREIWEHRADAASGLPLLQLGVALKTMGDATRGEEAIALALKTPRNSDERIWLGDYGS
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Template Sequence  LQEAKDICEEQVNSLPGSITKAGDFLEANYMNLQRSYTVAIAGYALAQMGRLKG. . . . . PLLNKFLTTAKDKNRWEDPGK
Template Known Secondary structure  TTTSTTT
TTGGG

STTT


.....TSBTTTB


SS
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   11291130.........1140.........1150.........1160.........1170.........1180.. .......1190.........1200...
 
   1385....1390.........1400.........1410........ .1420.........1430.........1440.... .....1450.........
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Query Sequence  . . . SLRDNALMLSLLEENKLLPDEQYTLLNTLSQQAF. GERWLSTQESNALFLAARTIQDLPGK. WQAQTSFSAEQLTGE
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Template Sequence  QLYNVEATSYALLALLQLKDFDFVPP. VVRWLNEQRYYGGGYGSTQATFMVFQALAQYQKDAPDHQELNLDVSLQLPSRS
Template Known Secondary structure  TT
TTT.T


BSSS

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TT
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   1204.....1210.........1220......... 1230.........1240.........1250.........1260.........1270.........1280..
 
   1460.........1470 .........1480.........1490.........1500.........1510.........1520........
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Query Sequence  KAQNSNLNSDQ. . . . . . . . . . . LVTLQVSNSGDQPLWLRMDASGYPQSAPLPANNVLQIERHILGTDGKSKSLDSLRSGD
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Template Conservation        
   
              
 
   
 
    
    
            
 
 
                   
Template Sequence  SKITHRIHWESASLLRSEETKENEGFTVTAEGKGQGTLSVVTMYHAKAKDQLTCNKFDLKVTIKPAPETEKRPQDAKNTM
Template Known Secondary structure  S
SSSS

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SS






S

SS

TTS


SS
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   1283......1290.........1300.........1310.........1320.........1330.........1340.........1350.........1360..
 
   15291530.........1540.........1550.........1560.........1570.........1580.........1590..... ....1600...
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Query Sequence  LVLVWLQVKASNSVPDALVVDLLPAGLELENQNLANGSASLEQSGGEVQNLLNQMQQASIKHIEFRD. . . . . DRFVAAVA
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Template Sequence  ILEICTRYRGDQDATMSILDISMMTGFAPDTDDLKQLANGVDRY. . . . . . . . . . . . . . . ISKYELDKAFSDRNTLIIYLD
Template Known Secondary structure 
SSS
B
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SS
SSS
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SSSS
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   1363......1370.........1380.........1390.........1400...... ...1410.........1420.......
 
   1604... ..1610.........1620........ .1630.........1640..
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Query Sequence  VDEY. QPVTLVYLARAVTPGTYQVPQ. PMVESMYVPQWRAT
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Template Sequence  KVSHSEDDCLAFKVHQYFNVELIQPGAVKVYAYYNLEESCT
Template Known Secondary structure 
B
SSS


SS
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TT
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   1428.1430.........1440.........1450.........1460........
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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