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Job DescriptionP76578
Confidence99.55%DateWed Jan 25 15:21:09 GMT 2012
Rank18Aligned Residues196
% Identity20%Templatec1o79A_
PDB info PDB header:isomeraseChain: A: PDB Molecule:squalene--hopene cyclase; PDBTitle: structures of human oxidosqualene cyclase inhibitors bound2 to a homolgous enzyme
Resolution2.8 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   1205....1210.........1220.........1230.........1240....... ..1250.........1260......
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Query Sequence  QLQALGIKGDSDEKRRASVDIGISRLLQMQRDNGGFALWDKNG. . . . . . . . . . . . . . . . . . DEEYWLTAYVMDFLVRAGE
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Template Sequence  VWALNTLRLPDERRRRDAMTKGFRWIVGMQSSNGGWGAYDVDNTSDLPNHIPFCDFGEVTDPPSEDVTAHVLECFGSF. .
Template Known Secondary structure  T


S
TT

TTS
B
SSSSSB

SSGGGSSS

SS

SB

B..
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   382.......390.........400.........410.........420.........430.........440.........450.........
 
   1267..1270.........1280.........1290.........1300.........1310.........1320.........1330.........1340......
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Query Sequence  QGYSVPTDAINRGNERLLRYLQDPGMMSIPYADNLKASKFAVQSYAALVLARQQKAPLGALREIWEHRADAASGLPLLQL
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Template Sequence  . GYDDAWKVIRRAVEYLKREQKPDGSWFGRW. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . GVNYLYGTGAV
Template Known Secondary structure  .T

TTS

TTS



SS......................................BS
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   460.........470.........480......... 490.........500
 
   1347..1350.........1360.........1370.........1380 .........1390.........1400. ........1410..
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Query Sequence  GVALKTMGDATRGEEAIALALKTPRNSDERIWLG. . . . . . . . . . . . . DYGSSLRDNALMLSLLEENKL. LPDEQYTLLNT
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Template Sequence  VSALKAVGIDTREPYIQKALDWVEQHQNPDGGWGEDCRSYEDPAYAGKGASTPSQTAWALMALIAGGRAESEAARRGVQY
Template Known Secondary structure  TT

TTSTTB
TTSSBB

GGGGT
GGGTT
S
B
TTTTSS
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   501........510.........520.........530.........540.........550.........560.........570.........580
 
   1413..... .1420... ......1430.........1440.
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Query Sequence  LSQQAF. GERWL. . . . . . . . . . . . . . . . . STQESNALFLAARTIQDL
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Template Sequence  LVETQRPDGGWDEPYYTGTGFPGDFYLGYTMYRHVFPTLALGRYKQA
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TTS




S

TTTTTT
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   581........590.........600.........610.........620.......
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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