|   |
19 | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | |
. | . | . | . | . | 40 | . | . | . | . | |
|
. | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | |
|
|
60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
| . |
|
|
|  |  |  |  |  |  |  | . | . |
|
|  |  |  |  |  |
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Q | T | V | S | L | A | A | G | D | Y | H | A | T | I | V | T | . |
V | G | A | G | L | A | E | L | T | F | . |
. |
Q | G | C | H | L | V | I | P | H | K | P | E | E | M | P | . |
. |
. |
L | A | H | L | G | K | V | L | I | P | W | P | N | R | I | A | N | G | C | Y | R | Y | Q | G | Q | E | Y | Q | L | P | I | N | E |
Query Conservation |   |
  |   |
|   |
|   |   |
|   |   |   |
|   |
|   |   | . |   |
|
|   |
|   |
|   |   |   | . | . |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   | . | . | . |   |   |   |   |
|   |   |
|   |
|   |   |
|
|
|   |   |   |   |   |   |   |   |
|   |   |
|   |
|   |   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |
|   |
|   |   |
|   |   |   |
|   |
|   |   |
|
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |
|
|
|   |   |   |   |   |   |   |   |
|   |   |
|   |
|   |   |   |   |
Template Sequence |   |
P | A | I | K | A | G | N | E | H | L | E | X | I | V | V | P | E | W | G | S | N | V | I | S | L | V | D | K | T | T | N | V | Q | L | L | R | E | P | E | T | A | E | S | F | H | D | T | P | T | L | Y | G | I | P | I | L | F | P | P | N | R | I | S | D | G | T | F | S | F | R | G | R | T | Y | H | F | D | I | N | E |
Template Known Secondary structure |   |
 |  |  |  |  |  |  | S | S |  |  |  |  |  |  | T | T | T | T | T |  |  |  |  |  |  |  | T | T | T | T |  |  |
| B |
|
|
| S | S |  |  |  |  |  |  |
| T | T | S | S | S |
|
|  |  | B | S |
| S |  |  |  | T | T |  |  |  |  | T | T |  |  |  |  |
|
|
|
| B |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|  |  |  |  |
|
|  |  |  |  |  |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
14 | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . |
  |
  |   |
93 | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | |
|
|
|
. | . | 120 | . | . | . | . | . | . | . | |
|
|
|
. | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|  | . | . | . | . |  |  |  |  |  |  |
|
|
|
| . | . | . | . |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
H | S | S | K | A | A | I | H | G | L | L | A | W | R | D | W | Q | I | S | E | L | T | A | T | S | . |
. |
. |
. |
V | T | L | T | A | F | L | P | P | S | . |
. |
. |
. |
Y | G | Y | P | F | M | L | A | S | Q | V | V | Y | S | L | N | A | H | T | G | L | S | V | E | I | A | S | Q | N | I | G | T | V | A | A | P | Y |
Query Conservation |   |
  |   |   |   |   |   |   |
|
|   |
|
|   |   |   |
|   |
|   |   |   |   |   |   |   | . | . | . | . |
|   |
|   |   |   |   |   |   |   | . | . | . | . |   |   |   |
|   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |
|   |
|   |   |   |
|   |
|   |
|   |   |   |   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |
|
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   | . |   |   |   |
|   |   |   |   |   |
|   |
|   |   |   |   |   |   |
|   |
Template Sequence |   |
K | D | K | H | N | H | L | H | G | F | L | Y | H | E | K | W | N | V | V | T | T | K | Q | T | D | E | G | V | I | V | E | T | E | I | D | L | S | E | L | P | H | V | Q | K | Q | F | P | H | H | A | V | V | R | X | T | Y | T | I | K | . |
E | N | T | L | F | K | H | A | T | V | X | N | K | G | K | E | A | F | P | W |
Template Known Secondary structure |   |
T | T | T | T |  |  |  | S | B | S |
| T | T | S |
|
|  |  |  |  |  |  |  |
| S | S |
|  |  |  |  |  |  |  |  | G | G | G |
|  |  |  |  |  |  | S |
| S |
|  |  |  |  |  |  |  |  |  |  | . | T | T |  |  |  |  |  |  |  |  |  |  |
| S | S | S |
|  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  | . |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
94 | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | |
. | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . |
  |
  |   |
165 | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | |
|
|
|
230 | . | . | . | . | . | . | . | . | . | 240 |
Predicted Secondary structure |   |
 |  |
|
|
|  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |
|
|
|
|
|
|
|  |  |  |  | . | . | . | . |  |
|
|
|
|  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | V | G | I | H | P | Y | L | T | C | N | L | T | S | V | D | E | Y | L | F | Q | L | P | A | N | Q | V | Y | A | V | D | E | H | A | N | P | T | T | L | H | H | V | D | E | L | D | L | N | F | T | Q | A | K | K | I | A | A | T | K | I | D | H | T | F | K | . |
. |
. |
. |
T | A | N | D | L | W | E | M | T | I | T |
Query Conservation |   |
  |   |
|   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |
|   |   |
|   | . | . | . | . |   |   |   |   |   |   |   |   |   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |
|
|
|
|   |   |   |   |   |   | . | . | . |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
Template Sequence |   |
G | I | G | Y | H | T | T | F | I | F | P | A | E | S | . |
. |
. |
S | L | F | S | L | T | A | D | Q | Q | W | E | L | D | E | R | L | L | P | T | G | K | L | X | D | V | P | Y | K | E | A | L | H | E | G | X | D | L | R | H | K | Q | L | D | D | V | F | L | S | S | Y | Q | K | R | G | G | E | N | Q | A | V | I | Y |
Template Known Secondary structure |   |
|
|  |  |
|
|
|  |  |
|
| T | T | T | . | . | . |  |  |  |  |  | S |  |  |  |  |  |  |  |
| T | T | S |
|  |  |  |  |  |  |  |
| T | T |  |  |  |  |  |  |
| B |
|
| T | T |
|
|
|  |  |  |  |  |  | S |  |  |  |  |
| S |
|
|  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |
|
|
|  |  |  |  |  |
|
|
|
| . | . | . |
|  |  |  |  |
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
173 | . | . | . | . | . | . | 180 | . | . | . | . | . | . | |
|
|
. | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . |
  |
  |   |
241 | . | . | . | . | . | . | . | . | 250 | . | |
|
. | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | |
|
|
|
|
. | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |
|
|
|
|  |  |  |  |  |  | . | . |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
H | P | Q | Q | A | L | S | V | S | L | C | . |
. |
S | D | Q | L | W | V | Q | V | Y | S | G | E | K | L | Q | R | Q | G | L | A | V | E | P | M | S | C | P | P | N | A | F | N | . |
. |
. |
. |
. |
S | G | I | D | L | L | L | L | E | S | G | K | P | H | R | L | F | F | N | I | Y | G | Q | R |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   | . | . |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |
|
|
|
|
|   |
|   |   |   |
|
|   |
| . | . | . | . | . |   |   |   |   |   |   |   |
|   |
|
|
|   |   |   |   |   |   |   |
|   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . |   |   |   |   |   |   |   |
|
|
|
|
|   |
|   |   |   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|   |   |   |   |   |   |   |
|   |
|
|   |
Template Sequence |   |
H | Q | H | A | H | I | S | I | I | Y | K | A | D | E | Q | F | K | H | W | V | V | Y | N | . |
A | D | G | K | Q | G | Y | L | C | P | E | P | Y | T | W | V | T | N | A | V | N | L | D | L | P | S | S | L | T | G | L | Q | V | L | E | P | G | E | E | T | T | A | K | S | S | I | T | I | E | L |
Template Known Secondary structure |   |
 | T | T | T | T |  |  |  |  |  |  |  |
| T | T |
|
|  |  |  |  |  |
| . | T | T | S |
| S | S |  |  |  |  |  |  |  | S | S |
| T | T | G | G | G |
|
| S |
|  |  |  |  |
|
|  |  |  |
| T | T |
|  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
| . |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | |
. | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . |
  |