|   |
1 | . | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | |
. | |
. | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  | . |
| . |
|
|  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . |
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
| . |
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
M | K | I | T | I | S | G | T | G | Y | V | G | L | S | N | G | L | L | I | A | . |
Q | . |
N | H | E | V | V | A | L | D | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
I | L | P | S | R | V | A | M | L | N | D | R | I | S | P | I | V | D | K | E | I | Q | Q | F | L | Q | S | D | K | I | H | F | N | A | T | L | D | K |
Query Conservation |   |
|
|
|   |
|
|
|
|
|   |
|
|
|   |
|
|   |   |
|
| . |   | . |
|   |   |
|   |
|   |
| . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |
|   |   |
|   |   |
|   |   |   |   |   |
|   |   |
|   |
|   |
|   |   |   |   |   |   |
|   |   |
|   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
| . |
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |
|
|
|   |
|   |
|
|   |   |   |
|   |   |
|   |   |
|   |
|
|   |
|
|
|
|
|
|   |   |
|   |
|   |
|
|   |
|
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |
Template Sequence |   |
A | T | V | A | V | Q | G | F | G | N | V | G | Q | F | A | A | L | L | I | S | Q | E | L | G | S | K | V | V | A | V | S | D | S | R | G | G | I | Y | N | P | E | G | F | D | V | E | E | L | I | R | Y | K | K | E | H | G | T | V | V | T | Y | P | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
K | G | E | R | I | T | N | E |
Template Known Secondary structure |   |
|  |  |  |  |  |
|
| S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  | T | T |  |  |  |  |
| T | T |
|
|
|  |  |  |  |  |  |  |  |  |  | S | S |
| S | T | T |
| S | . | . | . | . | . | . | . | . | . | . | S |
|  |  |  |
|  |  |
Template Predicted Secondary structure |   |
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|  |  |  |
|
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | |
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . |
  |
  |   |
68 | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
N | E | A | Y | R | D | A | D | Y | V | I | I | A | T | P | T | D | Y | D | P | K | T | N | Y | F | N | T | S | S | V | E | S | V | I | K | D | V | V | E | I | N | P | Y | A | V | M | V | I | K | S | T | V | P | V | G | F | T | A | A | M | H | K | K | Y | R | T | E | N | I | I | F | S | P | E | F | L | R | E | G | K |
Query Conservation |   |
  |   |   |   |   |   |
|
|
|
|
|
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |
|   |   |
|   |
|
|
|   |   |
|
|
|   |
|
|
|
|   |   |
|   |   |   |   |   |   |   |   |
|   |   |   |
|
|   |   |   |   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
Template Conservation |   |
  |
|   |   |   |   |   |
|
|
|   |
|   |
|   |   |   |   |
|   |   |   |   |
|   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |
|   |
|
|   |
|
|
|
|
|
|   |   | . |   |
|   |
|
|   |   |   |
|   |   |
|
|
|   |   |   |
|
|   |   |
| . | . | . |
Template Sequence |   |
E | L | L | E | L | D | V | D | I | L | V | P | A | A | L | E | G | A | I | H | A | G | N | A | E | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
R | I | K | A | K | A | V | V | E | G | A | N | G | P | . |
T | T | P | E | A | D | E | I | L | S | R | R | G | I | L | V | V | P | D | I | L | A | . |
. |
. |
Template Known Secondary structure |   |
 |  |  | T | S |
|
| S |  |  |  |  |
| S |
| T | T |
| B |
|  |  |  |  | T | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | T |
|
|
| S |  |  |  |
|
| S | S | S |
| . | B |
|  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |
|  |  |  |  | . | . | . |
Template Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |
|
|
|
|  |  |  |  |
|
|
|
|
| . |
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
|  |  |  |  | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | 310 | . | . | . | . | . | . | . | . | |
. | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | |
|
|
  |
  |   |
148 | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | L | Y | D | N | L | H | P | S | R | I | V | I | G | E | R | S | E | R | A | E | R | F | A | A | L | L | Q | E | G | A | I | K | Q | N | I | P | M | L | F | T | D | S | T | E | A | E | A | I | K | L | F | A | N | T | Y | L | A | M | R | V | A | Y | F | N | E | L | D | S | Y | A | E | S | L | G | L | N | S | R | Q |
Query Conservation |   |
|   |   |   |   |   |   |   |   |
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|
|   |   |
|
|   |   |
|   |   |   |   |   |   |
|
|   |   |
|
|   |   |   |
|   |
|   |   |
|
|
|   |   |   |
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |
Template Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
N | A | G | G | V | T | V | S | Y | F | E | W | V | Q | D | L | Q | S | F | F | W | D | L | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
D | Q | V | R | N | A | L | E | K | M | M | K | G | A | F | N | D | V | M | K | V | K | E | K | Y | N | V | D | M | R | T |
Template Known Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
|
|  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
|  |  |  |
Template Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
|
|
|
|
|
|
341 | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . |
  |
  |   |
228 | . | 230 | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
Query Sequence |   |
I | I | E | G | V | C |
Query Conservation |   |
|   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
Template Conservation |   |
|
|   |   |   |
|
Template Sequence |   |
A | A | Y | I | L | A |
Template Known Secondary structure |   |
 |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
  |   |
395 | . | . | . | . | 400 |
  |