|   |
2 | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
K | I | T | I | S | G | T | G | Y | V | G | L | S | N | G | L | L | I | A | Q | N | H | E | V | V | A | L | D | I | L | P | S | R | V | A | M | L | N | D | R | I | S | P | I | V | D | K | E | I | Q | Q | F | L | Q | S | D | K | I | H | F | N | A | T | L | D | K | N | E | A | Y | R | D | A | D | Y | V | I | I | A | T |
Query Conservation |   |
|
|   |
|
|
|
|
|   |
|
|
|   |
|
|   |   |
|
|   |
|   |   |
|   |
|   |
|   |   |   |   |   |
|   |   |
|   |   |
|   |   |   |   |   |
|   |   |
|   |
|   |
|   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|
|
|
|
|
|
|   |
|
|   |   |
|
|   |   |
|   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |
|
|   |   |
|
Template Sequence |   |
K | V | A | F | I | G | L | G | A | X | G | Y | P | X | A | G | H | L | A | R | R | F | P | T | L | V | W | N | R | T | F | E | K | A | L | R | H | Q | E | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
E | F | G | S | E | A | V | P | L | E | R | V | A | E | A | R | V | I | F | T | C | L |
Template Known Secondary structure |   |
|  |  |  |  |
|
| S | T | T |  |  |  |  |  |  |  |  |  |  |  | S |
|  |  |  |  |
| S | S |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |
|
|  |  |
|
| G | G | G | G | G | G | S | S |  |  |  |  |
|
|
Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
3 | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . |
  |
  |   |
82 | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | |
. | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | |
|
. | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | . |
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  | . | . |
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
P | T | D | Y | D | P | K | T | N | Y | F | N | T | S | S | V | E | S | V | I | K | D | V | V | E | . |
I | N | P | Y | A | V | M | V | I | K | S | T | V | P | V | G | F | T | A | A | M | H | K | K | Y | R | T | E | N | I | I | F | . |
. |
S | P | E | F | L | R | E | G | K | A | L | Y | D | N | L | H | P | S | R | I |
Query Conservation |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   | . |
|   |   |
|   |
|
|
|   |   |
|
|
|   |
|
|
|
|   |   |
|   |   |   |   |   |   |   |   |
|   |   | . | . |   |
|
|   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |
|
|
Alig confidence |   |
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
Template Conservation |   |
  |   |   | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |
|
|   |   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |
|   |   |   |   |   |   |
|   |   |
|   |   |   | . | . | . |   |
Template Sequence |   |
P | T | T | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
R | E | V | Y | E | V | A | E | A | L | Y | P | Y | L | R | E | G | T | Y | W | V | D | A | T | S | G | E | P | E | A | S | R | R | L | A | E | R | L | R | E | K | G | V | T | Y | L | D | A | P | V | S | G | G | T | S | G | A | E | A | G | T | L | T | . |
. |
. |
V |
Template Known Secondary structure |   |
S | S |  | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  | T | T | T |
|
| T | T |  |  |  |  |  |
| S |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  | T | T | T |  |  |  |  |  |
|
|  |  | S |  |  |  |  |  |  |  | T |
|  |  | . | . | . |  |
Template Predicted Secondary structure |   |
|
|
| . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  | . | . | . |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
64 | . | . | |
|
|
|
|
|
|
|
|
|
. | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | |
|
|
130 |
  |
  |   |
159 | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | I | G | E | R | S | E | R | A | E | R | F | A | A | L | L | Q | E | G | A | I | K | Q | N | I | P | M | L | F | T | D | S | T | E | A | E | A | I | K | L | F | A | N | T | Y | L | A | M | R | V | A | Y | F | N | E | L | D | S | Y | A | E | S | L | G | L | N | S | R | Q | I | I | E | G | V | C | L | D | P | R | I |
Query Conservation |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|
|   |   |
|
|   |   |
|   |   |   |   |   |   |
|
|   |   |
|
|   |   |   |
|   |
|   |   |
|
|
|   |   |   |
|   |   |   |   |   |   |   |   |
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   | . |   |   |   |   |   | . | . | . |   |   |   |   |   |   |   |
|   |
|   |   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
|   |   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
X | L | G | G | P | E | E | A | V | E | R | V | R | P | F | L | . |
A | Y | A | K | K | . |
. |
. |
V | V | H | V | G | P | V | G | A | G | H | A | V | K | A | I | N | N | A | L | L | A | V | N | L | W | A | A | G | E | G | L | L | A | L | V | K | Q | G | V | S | A | E | K | A | L | E | V | I | N | A | S | S | G | R |
Template Known Secondary structure |   |
 |  |  | S |
|  |  |  |  |  |  |  | G | G | G |
| . | T | T |  |  |  | . | . | . |  |  |  |  |  | S | T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|  |  |  |  |  |  |  |  | T | T | S | T | T |
|
Template Predicted Secondary structure |   |
 |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  | . |  |  |
|
|
| . | . | . |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
131 | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | |
. | . | . | 150 | . | |
|
|
. | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . |
  |
  |   |
239 | 240 | . | . | |
|
. | . | . | . | . | . | . | 250 | . | |
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | 260 | . | |
|
. | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
| . | . |
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|  |  |  |  |  |  |  | . | . |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | N | H | Y | . |
. |
N | N | P | S | F | G | Y | G | G | . |
. |
. |
. |
. |
. |
. |
. |
Y | C | L | P | K | D | T | K | Q | L | . |
. |
L | A | N | Y | Q | S | V | P | N | N | L | I | S | A | I | V | D | A | N | R | T | R | K | D | F | I | A | D | A | I | L | S | R | K | P | Q | V | V | G | I | Y | R | L | I | M |
Query Conservation |   |
|   |   |   | . | . |   |   |
|
|   |
|   |
|
| . | . | . | . | . | . | . | . |   |
|
|
|
|
|   |   |   |
| . | . |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|
|
|
|
Alig confidence |   |
|
|
|
| . | . |
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|
|   |   |   |   |   |   |   |
|   |   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Sequence |   |
S | N | A | T | E | N | L | I | P | Q | R | V | L | T | R | A | F | P | K | T | F | A | L | G | L | L | V | K | D | L | G | I | A | X | G | V | L | D | G | E | K | A | P | S | P | L | L | R | L | A | R | E | V | Y | E | X | A | K | R | E | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
|  |  |  |  |  | T |  |  |  |  | T | T | T | S |
|
|
|
| S | S | B |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | T |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |
|
|  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
207 | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |
  |   |
307 | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . |
Predicted Secondary structure |   |
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
K | S | G | S | D | N | F | R | A | S | S | I | Q | G | I | M | K | R | I | K | A | K | G | V | E |
Query Conservation |   |
|   |   |   |   |
|   |
|   |
|   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |
Alig confidence |   |
. | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. | . |
|   |   |   |   |
|   |
|
|
|   |   |   |   |   |   |   |   |
|   |   |   |   |
Template Sequence |   |
. |
. |
L | G | P | D | A | D | H | V | E | A | L | R | L | L | E | R | W | G | G | V | E | I | R |
Template Known Secondary structure |   |
. | . |  |
| T | T | S | B | G | G | G | G |  |  |  |  |  |  |  |  | T | S |
|
|
|
Template Predicted Secondary structure |   |
. | . |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
267 | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . |
  |