Secondary structure and disorder prediction

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Sequence		M	L	E	L	L	K	S	L	V	F	A	V	I	M	V	P	V	V	M	A	I	I	L	G	L	I	Y	G	L	G	E	V	F	N	I	F	S	G	V	G	K	K	D	Q	P	G	Q	N	H
Secondary structure
SS confidence
Disorder		?																																						?	?	?	?	?	?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 2ajm chain A Region: 22 - 34 Aligned: 13 Modelled: 13 Confidence: 23.7% Identity: 46% PDB header:membrane protein Chain: A: PDB Molecule:nonstructural protein 5a; PDBTitle: nmr structure of the in-plane membrane anchor domain [1-28]2 of the monotopic nonstructural protein 5a (ns5a) from the3 bovine viral diarrhea virus (bvdv) Phyre2 PDB 3din chain D Region: 3 - 36 Aligned: 34 Modelled: 34 Confidence: 19.6% Identity: 21% PDB header:membrane protein, protein transport Chain: D: PDB Molecule:preprotein translocase subunit sece; PDBTitle: crystal structure of the protein-translocation complex formed by the2 secy channel and the seca atpase Phyre2 PDB 1jb0 chain I Region: 12 - 29 Aligned: 18 Modelled: 18 Confidence: 7.9% Identity: 33% Fold: Single transmembrane helix Superfamily: Subunit VIII of photosystem I reaction centre, PsaI Family: Subunit VIII of photosystem I reaction centre, PsaI Phyre2 PDB 3g79 chain A Region: 38 - 49 Aligned: 12 Modelled: 12 Confidence: 7.3% Identity: 25% PDB header:oxidoreductase Chain: A: PDB Molecule:ndp-n-acetyl-d-galactosaminuronic acid dehydrogenase; PDBTitle: crystal structure of ndp-n-acetyl-d-galactosaminuronic acid2 dehydrogenase from methanosarcina mazei go1 Phyre2 PDB 1afo chain B Region: 16 - 37 Aligned: 22 Modelled: 22 Confidence: 6.4% Identity: 27% PDB header:integral membrane protein Chain: B: PDB Molecule:glycophorin a; PDBTitle: dimeric transmembrane domain of human glycophorin a, nmr,2 20 structures Phyre2 PDB 2kv5 chain A Region: 5 - 22 Aligned: 18 Modelled: 18 Confidence: 6.0% Identity: 50% PDB header:toxin Chain: A: PDB Molecule:putative uncharacterized protein rnai; PDBTitle: solution structure of the par toxin fst in dpc micelles Phyre2 1 c2ajmA_ 2 c3dinD_ 3 d1jb0i_ 4 c3g79A_ 5 c1afoB_ 6 c2kv5A_

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c2ajmA_ 23.7 46 PDB header:membrane protein Chain: A: PDB Molecule:nonstructural protein 5a; PDBTitle: nmr structure of the in-plane membrane anchor domain [1-28]2 of the monotopic nonstructural protein 5a (ns5a) from the3 bovine viral diarrhea virus (bvdv) 2 c3dinD_ 19.6 21 PDB header:membrane protein, protein transport Chain: D: PDB Molecule:preprotein translocase subunit sece; PDBTitle: crystal structure of the protein-translocation complex formed by the2 secy channel and the seca atpase 3 d1jb0i_ 7.9 33 Fold:Single transmembrane helix Superfamily:Subunit VIII of photosystem I reaction centre, PsaI Family:Subunit VIII of photosystem I reaction centre, PsaI 4 c3g79A_ 7.3 25 PDB header:oxidoreductase Chain: A: PDB Molecule:ndp-n-acetyl-d-galactosaminuronic acid dehydrogenase; PDBTitle: crystal structure of ndp-n-acetyl-d-galactosaminuronic acid2 dehydrogenase from methanosarcina mazei go1 5 c1afoB_ 6.4 27 PDB header:integral membrane protein Chain: B: PDB Molecule:glycophorin a; PDBTitle: dimeric transmembrane domain of human glycophorin a, nmr,2 20 structures 6 c2kv5A_ 6.0 50 PDB header:toxin Chain: A: PDB Molecule:putative uncharacterized protein rnai; PDBTitle: solution structure of the par toxin fst in dpc micelles

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Transmembrane helix prediction

Transmembrane helices have been predicted in your sequence to adopt the topology shown below

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0