|   |
225 | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | |
|
|
. | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | |
|
|
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
| . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
| . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
Query Sequence |   |
P | L | P | V | V | S | V | P | H | M | R | C | E | C | N | Q | S | D | E | E | F | G | G | V | V | R | L | L | Q | K | A | I | R | A | G | E | I | F | Q | V | V | P | S | R | R | F | S | L | P | C | P | . |
. |
. |
S | P | L | A | A | Y | Y | V | L | K | K | S | N | P | S | P | Y | M | F | F | M | Q | D | . |
. |
. |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |
|   |   |
|
|   |   |
|
|
|
|
|
|   |   |   |   |   |   |   | . | . | . |   |
|   |   |   |
|   |   |
|
|   |   |
|
|
|
|
|   |   |   |   |   |   | . | . | . |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |
|   |   |
|   |   |   |
|
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |   |   |
|   |   |
|   |
|   |   |   |   |   |   |   |
Template Sequence |   |
E | R | L | Q | L | D | N | L | T | F | E | X | T | P | V | P | D | H | E | V | Y | X | K | G | V | K | Q | G | I | E | K | I | K | D | G | D | L | K | K | I | V | L | S | R | S | L | D | V | K | S | S | G | K | I | D | K | Q | K | L | L | R | E | L | A | E | H | N | K | H | G | Y | T | F | A | V | N | L | P | K | D |
Template Known Secondary structure |   |
S |
|
|
|
|
|
|
|
|  |  |  |  |  |  | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | S |
| S |  |  |  |  |  |  |  |  |  |  |  |  | S | S |
|
|
|  |  |  |  |  |  |  |  |  |  | T |
| S | S | S |  |  |  |  |  |  |  |
|
|
|
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
95 | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . |
  |
  |   |
|
299 | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
. |
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Query SS confidence |   |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
N | D | F | T | L | F | G | A | S | P | E | S | S | L | K | Y | D | A | T | S | R | Q | I | E | I | Y | P | I | A | G | T | R | P | R | G | R | R | A | D | G | S | L | D | R | D | L | D | S | R | I | E | L | E | M | R | T | D | H | K | E | L | S | E | H | L | M | L | V | D | L | A | R | N | D | L | A | R | I | C |
Query Conservation |   |
. |   |   |   |   |
|
|
|
|
|
|
|   |
|
|   |   |   |   |   |   |   |   |
|   |
|   |
|
|
|
|
|   |   |
|
|   |
|   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |
|   |   |   |   |
|
|   |
|
|
|   |
|
|
|
|
|   |
|
|
|
|   |
|
|
|
Alig confidence |   |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |
|
|
|
|
|
|   |
|   |   |   |   | . | . |
|   |   |
|   |
|   |
|
|
|
|
|   |   |
|   |   |   |   | . | . | . | . | . | . |   |   |
|   |   |   |   |   |   |
|   |   |
|   |
|
|   |   |
|
|   |
|
|
|
|   |
|
|   |   |
|   |   |   |
|
Template Sequence |   |
E | N | S | K | T | L | I | G | A | S | P | E | L | L | V | S | R | H | . |
. |
G | X | Q | V | I | S | N | P | L | A | G | S | R | P | R | S | D | D | P | . |
. |
. |
. |
. |
. |
V | E | D | K | R | R | A | E | E | L | L | S | S | P | K | D | L | H | E | H | A | V | V | V | E | A | V | A | A | A | L | R | P | Y | C |
Template Known Secondary structure |   |
|
|
|  |  |  |  |  |  |  |
|
|  |  |  |  |  |  | . | . | T | T |  |  |  |  |
|
|  |  |  |  |  |  |
|
| S | S |  | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | G | G | G |  |
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  | . | . |
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
184 | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | |
|
. | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | |
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . |
  |
  |   |
378 | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | |
. | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|  |  |
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
| . |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
T | P | G | S | R | Y | V | A | D | L | T | K | V | D | R | Y | S | Y | V | M | H | L | V | S | R | V | V | G | E | L | R | . |
H | D | L | D | A | L | H | A | Y | R | A | C | M | N | M | G | T | L | S | G | A | P | K | V | R | A | M | Q | L | I | A | E | A | E | G | R | R | R | G | S | Y | G | G | A | V | G | Y | F |
Query Conservation |   |
  |   |
|
|
|   |
|   |   |   |   |   |
|
|   |   |   |   |
|   |
|
|
|
|   |
|   |
|   |
|   | . |   |   |   |   |   |   |
|   |
|   |   |   |
|
|   |
|
|
|
|
|
|
|
|   |
|
|   |
|
|
|   |
|
|
|   |   |   |
|
|   |
|   |
|   |
|
|   |
|
Alig confidence |   |
. | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. | . |   |
|
|   |
|   |   |   |   |   |
|   |   |   |   |   |
|   |
|
|   |
|   |
|   |
|   |
|   |   |   |   |   |   |   |   |
|
|
|   |
|
|
|
|
|   |
|
|   |
|   |
|
|   |   |
|   |   |   |
|   |   |   |
|   |   |   |
|
|   |
|   |
|   |
|
|   |   |
Template Sequence |   |
. |
. |
H | T | L | Y | V | P | E | K | P | S | V | I | H | S | E | A | X | W | H | L | S | T | E | V | K | G | E | L | K | N | P | N | T | S | S | L | E | L | A | I | A | L | H | P | T | P | A | V | C | G | T | P | X | E | E | A | R | E | A | I | Q | K | I | E | P | F | D | R | E | F | F | T | G | X | L | G | W | S |
Template Known Secondary structure |   |
. | . |  |  |  |  |
|
| S | S |
|  |  |  |  |
| S | S |  |  |  |  |  |
|
|  |  |  |  |  | S |
| T | T |
|
|  |  |  |  |  |  |  |  |
| S |
| T | T | T | S |  |  | S |  |  |  |  |  |  |  |  |  |  |  |
| S | S |
|
| T | T | T | T |
|  |  |  |  |  |
Template Predicted Secondary structure |   |
. | . |
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
258 | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . |
  |
  |   |
457 | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . |
Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |
|
|  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
T | A | H | G | D | L | D | T | C | I | V | I | R | S | A | L | V | E | N | G | I | A | T | V | Q | A | G | A | G | V | V | L | D | S | V | P | Q | S | E | A | D | E | T | R | N | K | A | R | A | V | L | R | A | I | A | T |
Query Conservation |   |
  |   |   |
|   |   |
|   |   |
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|
|   |
|
|   |
|   |   |
|   |   |
|
|   |   |
|   |   |   |   |
|   |
|
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |
|   |   |
|   |   |
|   |
|
|
|
|   |   |   |   |   |   |   |   |
|   |
|
|   |
|
|
|   |
|
|   |
|   |   |
|   |   |
|
|   |   |
|   |   |   |   |
|   |
|
|
|   |
Template Sequence |   |
D | L | N | G | D | G | E | W | I | V | T | I | R | C | A | E | V | Q | E | N | T | L | R | L | Y | A | G | A | G | V | V | A | E | S | K | P | E | D | E | L | A | E | T | S | A | K | F | Q | T | X | L | K | A | L | G | L |
Template Known Secondary structure |   |
 | T | T | S |
|  |  |  |  |  |
|
| S |  |  |  |  |  | T | T |  |  |  |  |  |  |  |  |  |  |
| T | T |
|
|  |  |  |  |  |  |  |  |  |  |  | T |  |  |  |  |  |  | T | T |
|
Template Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |
|
|  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
336 | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . |
  |